IL120343A0 - Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-YL)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide - Google Patents

Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-YL)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide

Info

Publication number
IL120343A0
IL120343A0 IL12034396A IL12034396A IL120343A0 IL 120343 A0 IL120343 A0 IL 120343A0 IL 12034396 A IL12034396 A IL 12034396A IL 12034396 A IL12034396 A IL 12034396A IL 120343 A0 IL120343 A0 IL 120343A0
Authority
IL
Israel
Prior art keywords
5alpha
17beta
androst
phenylprop
epimers
Prior art date
Application number
IL12034396A
Other languages
English (en)
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of IL120343A0 publication Critical patent/IL120343A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12034396A 1995-07-21 1996-06-28 Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-YL)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide IL120343A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001587A IT1275594B1 (it) 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide
PCT/EP1996/002830 WO1997004002A1 (en) 1995-07-21 1996-06-28 EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5α-ANDROST-1-ENE-17β-CARBOXAMIDE

Publications (1)

Publication Number Publication Date
IL120343A0 true IL120343A0 (en) 1997-06-10

Family

ID=11372032

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12034396A IL120343A0 (en) 1995-07-21 1996-06-28 Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-YL)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide

Country Status (17)

Country Link
EP (1) EP0782582A1 (hu)
JP (1) JPH10506411A (hu)
KR (1) KR970706298A (hu)
CN (1) CN1159195A (hu)
AR (1) AR003967A1 (hu)
AU (1) AU6418396A (hu)
BR (1) BR9606527A (hu)
CA (1) CA2199273A1 (hu)
EA (1) EA199700045A1 (hu)
HU (1) HUP9702465A3 (hu)
IL (1) IL120343A0 (hu)
IT (1) IT1275594B1 (hu)
MX (1) MX9701948A (hu)
NO (1) NO971196D0 (hu)
PL (1) PL319351A1 (hu)
WO (1) WO1997004002A1 (hu)
ZA (1) ZA965678B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000013509A1 (en) * 1998-09-09 2000-03-16 Merck & Co., Inc. Method of determining and reducing the risk of bph-related urologic events
ES2237408T3 (es) * 1999-01-25 2005-08-01 Smithkline Beecham Corporation Antiandrogenos y procedimientos para tratar una enfermedad.
CN100355772C (zh) * 2005-12-28 2007-12-19 天津大学 具有5α－还原酶抑制活性的甾体化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives

Also Published As

Publication number Publication date
HUP9702465A2 (hu) 1998-05-28
EP0782582A1 (en) 1997-07-09
HUP9702465A3 (en) 1998-11-30
ITMI951587A1 (it) 1997-01-21
CA2199273A1 (en) 1997-02-06
ZA965678B (en) 1997-01-24
AU6418396A (en) 1997-02-18
JPH10506411A (ja) 1998-06-23
AR003967A1 (es) 1998-09-30
NO971196L (no) 1997-03-14
ITMI951587A0 (it) 1995-07-21
BR9606527A (pt) 1997-12-23
EA199700045A1 (ru) 1997-12-30
KR970706298A (ko) 1997-11-03
IT1275594B1 (it) 1997-08-06
CN1159195A (zh) 1997-09-10
NO971196D0 (no) 1997-03-14
PL319351A1 (en) 1997-08-04
WO1997004002A1 (en) 1997-02-06
MX9701948A (es) 1997-06-28

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