IL120056A - History of Naphtali - Google Patents
History of NaphtaliInfo
- Publication number
- IL120056A IL120056A IL120056A IL12005693A IL120056A IL 120056 A IL120056 A IL 120056A IL 120056 A IL120056 A IL 120056A IL 12005693 A IL12005693 A IL 12005693A IL 120056 A IL120056 A IL 120056A
- Authority
- IL
- Israel
- Prior art keywords
- mixture
- ch3o
- bis
- give
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Lubricants (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4085118A JP3042156B2 (ja) | 1992-02-20 | 1992-02-20 | ナフタレン誘導体、その製法及びその合成中間体 |
IL104773A IL104773A (en) | 1992-02-20 | 1993-02-18 | Naphthalene derivatives, their preparation and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
IL120056A true IL120056A (en) | 1998-02-08 |
Family
ID=13849719
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL120056A IL120056A (en) | 1992-02-20 | 1993-02-18 | History of Naphtali |
IL104773A IL104773A (en) | 1992-02-20 | 1993-02-18 | Naphthalene derivatives, their preparation and pharmaceutical compositions containing them |
IL12005697A IL120056A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
IL12005797A IL120057A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL104773A IL104773A (en) | 1992-02-20 | 1993-02-18 | Naphthalene derivatives, their preparation and pharmaceutical compositions containing them |
IL12005697A IL120056A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
IL12005797A IL120057A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
Country Status (17)
Country | Link |
---|---|
US (1) | US5342941A (ja) |
EP (1) | EP0557016B1 (ja) |
JP (1) | JP3042156B2 (ja) |
KR (1) | KR100199121B1 (ja) |
CN (1) | CN1045435C (ja) |
AT (1) | ATE139528T1 (ja) |
AU (1) | AU658046B2 (ja) |
CA (1) | CA2089906C (ja) |
DE (1) | DE69303191T2 (ja) |
DK (1) | DK0557016T3 (ja) |
ES (1) | ES2090855T3 (ja) |
FI (1) | FI102277B1 (ja) |
GR (1) | GR3020294T3 (ja) |
HK (1) | HK98997A (ja) |
IL (4) | IL120056A (ja) |
MY (1) | MY108891A (ja) |
TW (1) | TW224458B (ja) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL118469A (en) * | 1995-06-15 | 2000-08-13 | Tanabe Seiyaku Co | Naphthalene derivatives their preparation and intermediates thereof |
ID19155A (id) * | 1996-12-13 | 1998-06-18 | Tanabe Seiyaku Co | Turunan-turunan piridin, pembuatannya dan intermediet untuk pembuatannya |
DE19755480A1 (de) * | 1997-12-13 | 1999-06-24 | Gruenenthal Gmbh | Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen |
JPH11209350A (ja) | 1998-01-26 | 1999-08-03 | Eisai Co Ltd | 含窒素複素環誘導体およびその医薬 |
US6465495B1 (en) * | 1998-07-30 | 2002-10-15 | Osi Pharmaceuticals, Inc. | Preparation of pyridone-based phosphotyrosine mimetics and uses thereof |
CA2715683A1 (en) | 1999-08-21 | 2001-03-01 | Nycomed Gmbh | Synergistic combination |
WO2002094321A1 (fr) | 2001-05-23 | 2002-11-28 | Tanabe Seiyaku Co., Ltd. | Compositions favorisant la guérison d'une fracture osseuse |
ES2427930T3 (es) * | 2001-05-23 | 2013-11-04 | Mitsubishi Tanabe Pharma Corporation | Composición terapéutica para el tratamiento regenerativo de enfermedades de los cartílagos |
TWI221838B (en) | 2001-08-09 | 2004-10-11 | Tanabe Seiyaku Co | Pyrazinoisoquinoline compound or naphthalene compound |
AU2004226353A1 (en) | 2003-04-01 | 2004-10-14 | Laboratoires Serono Sa | Inhibitors of phosphodiesterases in infertility |
TWI339578B (en) * | 2004-10-29 | 2011-04-01 | Mitsubishi Tanabe Pharma Corp | Use of a pyridine compound for the preparation of a medicament for the treatment of skin lesions |
TWI417095B (zh) | 2006-03-15 | 2013-12-01 | Janssen Pharmaceuticals Inc | 1,4-二取代之3-氰基-吡啶酮衍生物及其作為mGluR2-受體之正向異位性調節劑之用途 |
WO2007112347A1 (en) * | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
CN101801951B (zh) | 2007-09-14 | 2013-11-13 | 杨森制药有限公司 | 1’,3’-二取代的-4-苯基-3,4,5,6-四氢-2h,1’h-[1,4’]二吡啶-2’-酮 |
ES2439291T3 (es) | 2008-09-02 | 2014-01-22 | Janssen Pharmaceuticals, Inc. | Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos |
US8691813B2 (en) | 2008-11-28 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
MX2011011962A (es) | 2009-05-12 | 2012-02-28 | Janssen Pharmaceuticals Inc | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostericos positivos de receptores de glutamato metabotropico (mglur2). |
ME01573B (me) | 2009-05-12 | 2014-09-20 | Addex Pharma Sa | DERIVATI 1,2,4-TRIAZOLO[4,3-a]PIRIDINA I NJIHOVA UPOTREBA U TRETMANU ILI PREVENCIJI NEUROLOŠKIH I PSIHIJATRIJSKIH POREMEĆAJA |
US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
AU2011328195B2 (en) | 2010-11-08 | 2015-04-02 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
JP5852666B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
PL3096790T3 (pl) | 2014-01-21 | 2020-01-31 | Janssen Pharmaceutica, N.V. | Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie |
KR20200036063A (ko) | 2014-01-21 | 2020-04-06 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA825413B (en) * | 1981-08-26 | 1983-06-29 | Pfizer | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them |
US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
US4792556A (en) * | 1985-09-09 | 1988-12-20 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
WO1989003681A1 (en) * | 1987-10-19 | 1989-05-05 | Pfizer Inc. | Substituted tetralins, chromans and related compounds in the treatment of asthma |
GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
DE3837464A1 (de) * | 1988-11-04 | 1990-05-10 | Bayer Ag | (hetero)aryloxynaphthalinderivate, verfahren und neue (hetero)aryloxynaphthylamine zu ihrer herstellung sowie ihre verwendung als herbizide |
GB8916683D0 (en) * | 1989-07-21 | 1989-09-06 | Beecham Group Plc | Novel compounds |
US5182296A (en) * | 1989-10-26 | 1993-01-26 | Tanabe Seiyaky Co., Ltd. | Naphthyloxazolidone derivatives |
IL98526A0 (en) * | 1990-06-18 | 1992-07-15 | Merck & Co Inc | Pyridones,processes for their preparation and pharmaceutical compositions containing them |
US5272170A (en) * | 1990-12-05 | 1993-12-21 | J. Uriach & Cia., S.A. | Tetralones with pharmacological activity |
EP0489300A3 (en) * | 1990-12-05 | 1993-03-17 | J. Uriach & Cia. S.A. | New tetralones with pharmacological activity |
FR2671551B1 (fr) * | 1991-01-15 | 1993-03-12 | Adir | Nouveaux composes de structure aryl triazinique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
RU2059603C1 (ru) * | 1991-05-09 | 1996-05-10 | Хоффманн-Ля Рош АГ | ПРОИЗВОДНЫЕ α -ЗАМЕЩЕННЫХ АРИЛУКСУСНЫХ КИСЛОТ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ |
-
1992
- 1992-02-20 JP JP4085118A patent/JP3042156B2/ja not_active Expired - Lifetime
-
1993
- 1993-02-11 DK DK93300998.7T patent/DK0557016T3/da active
- 1993-02-11 AT AT93300998T patent/ATE139528T1/de not_active IP Right Cessation
- 1993-02-11 EP EP93300998A patent/EP0557016B1/en not_active Expired - Lifetime
- 1993-02-11 ES ES93300998T patent/ES2090855T3/es not_active Expired - Lifetime
- 1993-02-11 DE DE69303191T patent/DE69303191T2/de not_active Expired - Fee Related
- 1993-02-11 AU AU32952/93A patent/AU658046B2/en not_active Ceased
- 1993-02-18 IL IL120056A patent/IL120056A/en not_active IP Right Cessation
- 1993-02-18 TW TW082101129A patent/TW224458B/zh active
- 1993-02-18 FI FI930711A patent/FI102277B1/fi active
- 1993-02-18 IL IL104773A patent/IL104773A/xx not_active IP Right Cessation
- 1993-02-18 KR KR1019930002269A patent/KR100199121B1/ko not_active IP Right Cessation
- 1993-02-18 MY MYPI93000270A patent/MY108891A/en unknown
- 1993-02-19 CA CA002089906A patent/CA2089906C/en not_active Expired - Fee Related
- 1993-02-19 US US08/019,885 patent/US5342941A/en not_active Expired - Fee Related
- 1993-02-20 CN CN93102013A patent/CN1045435C/zh not_active Expired - Fee Related
-
1996
- 1996-06-20 GR GR960401544T patent/GR3020294T3/el unknown
-
1997
- 1997-01-23 IL IL12005697A patent/IL120056A0/xx unknown
- 1997-01-23 IL IL12005797A patent/IL120057A0/xx unknown
- 1997-06-26 HK HK98997A patent/HK98997A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL120056A0 (en) | 1997-04-15 |
ES2090855T3 (es) | 1996-10-16 |
FI930711A0 (fi) | 1993-02-18 |
FI102277B (fi) | 1998-11-13 |
MY108891A (en) | 1996-11-30 |
DK0557016T3 (da) | 1996-07-15 |
CN1045435C (zh) | 1999-10-06 |
IL104773A0 (en) | 1993-06-10 |
CN1075957A (zh) | 1993-09-08 |
JP3042156B2 (ja) | 2000-05-15 |
KR100199121B1 (ko) | 1999-06-15 |
EP0557016B1 (en) | 1996-06-19 |
EP0557016A1 (en) | 1993-08-25 |
IL104773A (en) | 1997-07-13 |
KR930017851A (ko) | 1993-09-20 |
AU658046B2 (en) | 1995-03-30 |
TW224458B (ja) | 1994-06-01 |
IL120057A0 (en) | 1997-04-15 |
ATE139528T1 (de) | 1996-07-15 |
GR3020294T3 (en) | 1996-09-30 |
CA2089906A1 (en) | 1993-08-21 |
FI102277B1 (fi) | 1998-11-13 |
DE69303191T2 (de) | 1996-11-14 |
CA2089906C (en) | 1998-08-18 |
DE69303191D1 (de) | 1996-07-25 |
US5342941A (en) | 1994-08-30 |
FI930711A (fi) | 1993-08-21 |
JPH05229987A (ja) | 1993-09-07 |
AU3295293A (en) | 1993-08-26 |
HK98997A (en) | 1997-08-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL120056A (en) | History of Naphtali | |
Buckle et al. | Studies on 1, 2, 3-triazoles. 13.(Piperazinylalkoxy)-[1] benzopyrano [2, 3-d]-1, 2, 3-triazol-9 (1H)-ones with combined H1-antihistamine and mast cell stabilizing properties | |
KR100435247B1 (ko) | 나프탈렌유도체,그의제조방법,및그의중간체 | |
Kubo et al. | Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of benzimidazolecarboxylic acids | |
EP0664291B1 (en) | Pyrimidine compound | |
FI90079C (fi) | Foerfarande foer framstaellning av terapeutiskt anvaenbara bensopyranderivat | |
EP0126311B1 (en) | Benzopyran derivatives. | |
US4490374A (en) | 5,6-Dialkoxy-3,4-optionally substituted-2(1H)quinazolinones, composition and method of use | |
AU641953B2 (en) | Benzoxazine derivatives, pharmaceutical compositions containing them and processes for their production | |
DE69000438T2 (de) | Heterocyclische derivate. | |
EP0558094A1 (en) | Pyridine compounds for treating amnesia | |
SU1232145A3 (ru) | Способ получени производных пиримидона или их фармацевтически приемлемых солей | |
CA2125725A1 (en) | Urea derivative containing heterocyclic ring | |
JPH07101861A (ja) | 抗喘息薬 | |
DD204924A5 (de) | Verfahren zur herstellung n-substituierter 2-pyridylindole | |
CA1068698A (en) | Process for preparing substituted aminoquinazoline derivatives and intermediates therefor | |
CA2028538A1 (en) | 4-substituted isoquinolone derivatives, their production and use | |
US4294969A (en) | Process for producing 2-bromo-3,5-disubstituted pyridines | |
EP0950056B1 (en) | N-(pyridinylamino)isoindolines and related compounds | |
US4631283A (en) | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | |
US4279913A (en) | Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines | |
US6004977A (en) | N-(pyridinylamino) isoindolines and related compounds | |
Castillo-Aguilera et al. | Study of the Effect of Substituents of ortho-Phenylenediamines in the Opening of Lactones and Lactams for Access to Benzimidazol-2-yl Alkanols and Benzimidazol-2-yl Alkylamines | |
US4393212A (en) | Certain nicotinic acid esters and corresponding nicotinonitriles | |
US5077302A (en) | Urea derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
RH1 | Patent not in force |