IL117170A - Nonatetraenoic acid derivatives and pharmaceutical compositions containing them - Google Patents
Nonatetraenoic acid derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL117170A IL117170A IL11717096A IL11717096A IL117170A IL 117170 A IL117170 A IL 117170A IL 11717096 A IL11717096 A IL 11717096A IL 11717096 A IL11717096 A IL 11717096A IL 117170 A IL117170 A IL 117170A
- Authority
- IL
- Israel
- Prior art keywords
- acid derivatives
- pharmaceutical compositions
- compositions containing
- nonatetraenoic acid
- nonatetraenoic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/38—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
- C07C47/45—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/548—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Vapour Deposition (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39398095A | 1995-02-24 | 1995-02-24 | |
| US46828995A | 1995-06-06 | 1995-06-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117170A0 IL117170A0 (en) | 1996-06-18 |
| IL117170A true IL117170A (en) | 2000-11-21 |
Family
ID=27014530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11717096A IL117170A (en) | 1995-02-24 | 1996-02-19 | Nonatetraenoic acid derivatives and pharmaceutical compositions containing them |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5986131A (ko) |
| EP (1) | EP0728742B1 (ko) |
| JP (1) | JP2776787B2 (ko) |
| KR (1) | KR100414342B1 (ko) |
| CN (1) | CN1124260C (ko) |
| AT (1) | ATE185799T1 (ko) |
| AU (1) | AU703115B2 (ko) |
| CA (1) | CA2170227A1 (ko) |
| CZ (1) | CZ291352B6 (ko) |
| DE (1) | DE69604713T2 (ko) |
| DK (1) | DK0728742T3 (ko) |
| ES (1) | ES2138765T3 (ko) |
| FI (1) | FI960856A (ko) |
| GR (1) | GR3032407T3 (ko) |
| HK (1) | HK1012330A1 (ko) |
| HU (1) | HU219538B (ko) |
| IL (1) | IL117170A (ko) |
| MA (1) | MA23813A1 (ko) |
| MY (1) | MY113430A (ko) |
| NO (1) | NO309189B1 (ko) |
| NZ (1) | NZ286017A (ko) |
| RU (1) | RU2166499C2 (ko) |
| SG (1) | SG59945A1 (ko) |
| TW (1) | TW343966B (ko) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69835441T2 (de) * | 1997-11-12 | 2007-08-02 | F. Hoffmann-La Roche Ag | Behandlung von t-helfer zell typ 2 vermittelten immunkrankheiten mit retinoid antagonisten |
| US6326397B1 (en) | 1998-11-10 | 2001-12-04 | Hoffman-La Roche Inc. | Retinoid antagonists and use thereof |
| JP4543513B2 (ja) * | 2000-07-17 | 2010-09-15 | ソニー株式会社 | 双方向通信システム、表示装置、ベース装置および双方向通信方法 |
| EP1935869A1 (en) | 2000-10-02 | 2008-06-25 | F. Hoffmann-La Roche Ag | Retinoids for the treatment of emphysema |
| US7312247B2 (en) | 2001-03-27 | 2007-12-25 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US8026280B2 (en) | 2001-03-27 | 2011-09-27 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US7842727B2 (en) | 2001-03-27 | 2010-11-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US7057057B2 (en) | 2002-05-22 | 2006-06-06 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors based on alpha-ketoepoxide compounds |
| US6495719B2 (en) | 2001-03-27 | 2002-12-17 | Circagen Pharmaceutical | Histone deacetylase inhibitors |
| JP2006508986A (ja) | 2002-11-20 | 2006-03-16 | エルラント ゲネ セラペウチクス エルエルシー | ヒストンデアセチラーゼ阻害剤による肺細胞の治療方法 |
| EP1771163A1 (en) * | 2004-07-29 | 2007-04-11 | Werner Bollag | Rxr antagonist treatment against multiple sclerosis |
| EP1621191A1 (en) * | 2004-07-29 | 2006-02-01 | Werner Bollag | Treatment of inflammatory diseases by RXR Antagonists |
| WO2007048510A1 (en) * | 2005-10-25 | 2007-05-03 | Werner Bollag | Rxr agonists and antagonists, alone or in combination with ppar ligands, in the treatment of metabolic and cardiovascular diseases |
| CN105646311B (zh) * | 2016-03-31 | 2017-09-26 | 广州巨元生化有限公司 | 一种制备β‑阿朴‑8’‑胡萝卜醛的方法 |
| EP3301085A1 (en) * | 2016-09-29 | 2018-04-04 | Biogem S.Ca.R.L. | Retinoid derivatives with antitumor activity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3277147A (en) * | 1963-06-05 | 1966-10-04 | Olin Mathieson | Lower alkyl esters of beta-cyclocitrylidene fluoroacetic acid and beta-ionylidene fluoroacetic acid |
| US5514672A (en) * | 1981-02-17 | 1996-05-07 | Bazzano; Gail S. | Use of retinoids and compositions containing same for hair growth |
| WO1995004036A1 (en) * | 1993-01-11 | 1995-02-09 | Ligand Pharmaceuticals Inc. | Compounds having selective activity for retinoid x receptors, and means for modulation of processes mediated by retinoid x receptors |
| IL116259A (en) * | 1994-12-19 | 2000-07-16 | American Cyanamid Co | Analogs of 9-cis retinoic acid and their use |
-
1996
- 1996-02-14 ES ES96102137T patent/ES2138765T3/es not_active Expired - Lifetime
- 1996-02-14 AT AT96102137T patent/ATE185799T1/de not_active IP Right Cessation
- 1996-02-14 DE DE69604713T patent/DE69604713T2/de not_active Expired - Fee Related
- 1996-02-14 DK DK96102137T patent/DK0728742T3/da active
- 1996-02-14 TW TW085101815A patent/TW343966B/zh active
- 1996-02-14 EP EP96102137A patent/EP0728742B1/en not_active Expired - Lifetime
- 1996-02-15 CN CN96102022A patent/CN1124260C/zh not_active Expired - Fee Related
- 1996-02-16 MY MYPI96000610A patent/MY113430A/en unknown
- 1996-02-19 AU AU45617/96A patent/AU703115B2/en not_active Ceased
- 1996-02-19 NZ NZ286017A patent/NZ286017A/en unknown
- 1996-02-19 IL IL11717096A patent/IL117170A/xx not_active IP Right Cessation
- 1996-02-22 CZ CZ1996537A patent/CZ291352B6/cs not_active IP Right Cessation
- 1996-02-22 SG SG1996003689A patent/SG59945A1/en unknown
- 1996-02-22 RU RU96103662/04A patent/RU2166499C2/ru not_active IP Right Cessation
- 1996-02-23 CA CA002170227A patent/CA2170227A1/en not_active Abandoned
- 1996-02-23 KR KR1019960004376A patent/KR100414342B1/ko not_active IP Right Cessation
- 1996-02-23 HU HU9600424A patent/HU219538B/hu unknown
- 1996-02-23 MA MA24170A patent/MA23813A1/fr unknown
- 1996-02-23 JP JP8036459A patent/JP2776787B2/ja not_active Expired - Fee Related
- 1996-02-23 NO NO960751A patent/NO309189B1/no unknown
- 1996-02-23 FI FI960856A patent/FI960856A/fi unknown
-
1997
- 1997-10-17 US US08/953,361 patent/US5986131A/en not_active Expired - Fee Related
-
1998
- 1998-12-15 HK HK98113449A patent/HK1012330A1/xx not_active IP Right Cessation
-
2000
- 2000-01-19 GR GR20000400104T patent/GR3032407T3/el not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |