IL115222A - Injectable liposomal pharmaceutical preparations containing a stabilizer - Google Patents

Injectable liposomal pharmaceutical preparations containing a stabilizer

Info

Publication number
IL115222A
IL115222A IL11522295A IL11522295A IL115222A IL 115222 A IL115222 A IL 115222A IL 11522295 A IL11522295 A IL 11522295A IL 11522295 A IL11522295 A IL 11522295A IL 115222 A IL115222 A IL 115222A
Authority
IL
Israel
Prior art keywords
stabilizer
pharmaceutical preparations
preparations containing
phospholipid
liposomal pharmaceutical
Prior art date
Application number
IL11522295A
Other languages
English (en)
Other versions
IL115222A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL115222A0 publication Critical patent/IL115222A0/xx
Publication of IL115222A publication Critical patent/IL115222A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y10S977/907—Liposome
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)
  • Glass Compositions (AREA)
IL11522295A 1994-09-12 1995-09-08 Injectable liposomal pharmaceutical preparations containing a stabilizer IL115222A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4432378A DE4432378A1 (de) 1994-09-12 1994-09-12 Injizierbare liposomale Arzneizubereitungen

Publications (2)

Publication Number Publication Date
IL115222A0 IL115222A0 (en) 1995-12-31
IL115222A true IL115222A (en) 1999-06-20

Family

ID=6527981

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11522295A IL115222A (en) 1994-09-12 1995-09-08 Injectable liposomal pharmaceutical preparations containing a stabilizer

Country Status (28)

Country Link
US (1) US5653998A (et)
EP (1) EP0700679B1 (et)
JP (1) JPH0881361A (et)
KR (1) KR960009998A (et)
CN (1) CN1079668C (et)
AT (1) ATE187327T1 (et)
AU (1) AU698441B2 (et)
CA (1) CA2157849A1 (et)
CZ (1) CZ287975B6 (et)
DE (2) DE4432378A1 (et)
DK (1) DK0700679T3 (et)
EE (1) EE03377B1 (et)
ES (1) ES2139800T3 (et)
FI (1) FI954204L (et)
GR (1) GR3032664T3 (et)
HU (1) HUT73808A (et)
IL (1) IL115222A (et)
MY (1) MY111841A (et)
NO (1) NO311556B1 (et)
NZ (1) NZ272943A (et)
PL (1) PL181541B1 (et)
PT (1) PT700679E (et)
RU (1) RU2160099C2 (et)
SI (1) SI0700679T1 (et)
SK (1) SK281611B6 (et)
TW (1) TW359616B (et)
UA (1) UA29469C2 (et)
ZA (1) ZA957604B (et)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
DE19709704C2 (de) * 1997-03-10 1999-11-04 Michael Georgieff Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie
US7030155B2 (en) 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
KR20000003433A (ko) * 1998-06-29 2000-01-15 김영환 반도체소자의 커패시터 제조방법
WO2000029103A1 (en) * 1998-11-13 2000-05-25 Optime Therapeutics, Inc. Method and apparatus for liposome production
AU773385B2 (en) * 1999-05-14 2004-05-27 Esperion Luv Development, Inc. Method of treating angina and/or anginal equivalents, and pharmaceutical compositions and kit related thereto
DE60123583T2 (de) 2000-02-04 2007-08-09 Lipoxen Technologies Ltd. Dehydratisierungs-/rehydratisierungsverfahren zur herstellung von liposome
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
EP1530465B2 (en) 2002-06-26 2015-12-16 MediGene AG Method of producing a cationic liposomal preparation comprising a lipophilic compound
DE10255195A1 (de) * 2002-11-27 2004-06-09 Lipoid Gmbh Micellare wasserlösliche Konzentrate
JP2007522085A (ja) * 2003-06-27 2007-08-09 スミスクライン・ビーチャム・コーポレイション 安定化されたトポテカンリポソーム組成物および方法
US7345093B2 (en) * 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
WO2006094203A1 (en) * 2005-03-02 2006-09-08 Northeastern University Mitochondriotropic phospholipid vesicles
PL1888033T3 (pl) * 2005-06-09 2014-09-30 Meda Ab Sposób i kompozycja do leczenia chorób zapalnych
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
JP5178520B2 (ja) 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
EP2034961A1 (de) * 2006-06-30 2009-03-18 Gertrud Langhoff Solubilisatformulierungen
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
CA2781527C (en) * 2009-09-23 2017-10-24 Indu Javeri Methods for the preparation of liposomes
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
IT1404011B1 (it) 2010-12-03 2013-11-08 Uni Degli Studi Magna Graecia Di Catanzaro Nanovettore coniugato con tsh per il trattamento del cancro della tiroide
PL226015B1 (pl) * 2011-03-03 2017-06-30 Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Liposomowy preparat zawierajacy przeciwnowotworowa substancje aktywna, sposob jego wytwarzania i zawierajaca go kompozycja farmaceutyczna
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
ES2992024T3 (es) 2011-06-23 2024-12-05 Dsm Ip Assets Bv Nuevos copolímeros de poliesteramida biodegradables para la administración de fármacos
FR2979239A1 (fr) * 2011-08-25 2013-03-01 Trophos Liposome comprenant au moins un derive de cholesterol
EP2682106A1 (en) 2012-07-03 2014-01-08 Phares Pharmaceutical Research N.V. Method of solubilizing biologically active compounds
US9775789B2 (en) * 2012-12-06 2017-10-03 D & J Rosée Inc. Topical liposome compositions containing phenolic anti-inflammatory agents and their methods of preparation
US10434071B2 (en) 2014-12-18 2019-10-08 Dsm Ip Assets, B.V. Drug delivery system for delivery of acid sensitivity drugs
CA3160955A1 (en) 2019-11-12 2021-05-20 Dsm Ip Assets B.V. Polyesteramide copolymers possessing high glass transition temperatures
CN110898011B (zh) * 2019-11-27 2022-02-08 西南医科大学 一种依托咪酯纳米制剂及其制备方法
WO2021130170A1 (en) * 2019-12-23 2021-07-01 Zambon S.P.A. Process for the preparation of dispersions comprising inhalable immunosuppressive active ingredients
JP7608086B2 (ja) * 2020-07-31 2025-01-06 東和薬品株式会社 シームレスカプセル

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4117750A1 (de) * 1991-05-30 1992-12-24 Bayer Ag Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4207481A1 (de) * 1992-03-10 1993-09-16 Bayer Ag Liposomale wirkstoff-formulierungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
SK281611B6 (sk) 2001-05-10
AU698441B2 (en) 1998-10-29
FI954204A7 (fi) 1996-03-13
EP0700679B1 (de) 1999-12-08
DE59507372D1 (de) 2000-01-13
PT700679E (pt) 2000-05-31
IL115222A0 (en) 1995-12-31
ATE187327T1 (de) 1999-12-15
NO953578D0 (no) 1995-09-11
EP0700679A1 (de) 1996-03-13
CZ287975B6 (cs) 2001-03-14
NO953578L (no) 1996-03-13
RU2160099C2 (ru) 2000-12-10
PL310344A1 (en) 1996-03-18
DE4432378A1 (de) 1996-03-14
CZ234195A3 (en) 1996-03-13
ZA957604B (en) 1996-04-15
FI954204L (fi) 1996-03-13
EE03377B1 (et) 2001-04-16
MY111841A (en) 2001-01-31
NO311556B1 (no) 2001-12-10
UA29469C2 (uk) 2000-11-15
SK112795A3 (en) 1997-02-05
HUT73808A (en) 1996-09-30
PL181541B1 (pl) 2001-08-31
CN1079668C (zh) 2002-02-27
CN1128655A (zh) 1996-08-14
NZ272943A (en) 1996-07-26
HU9502654D0 (en) 1995-11-28
SI0700679T1 (en) 2000-02-29
AU3046495A (en) 1996-03-28
EE9500063A (et) 1996-04-15
DK0700679T3 (da) 2000-05-29
JPH0881361A (ja) 1996-03-26
CA2157849A1 (en) 1996-03-13
GR3032664T3 (en) 2000-06-30
KR960009998A (ko) 1996-04-20
FI954204A0 (fi) 1995-09-08
TW359616B (en) 1999-06-01
US5653998A (en) 1997-08-05
ES2139800T3 (es) 2000-02-16

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