IL114185A0 - - Google Patents
Info
- Publication number
- IL114185A0 IL114185A0 IL11418595A IL11418595A IL114185A0 IL 114185 A0 IL114185 A0 IL 114185A0 IL 11418595 A IL11418595 A IL 11418595A IL 11418595 A IL11418595 A IL 11418595A IL 114185 A0 IL114185 A0 IL 114185A0
- Authority
- IL
- Israel
- Prior art keywords
- useful
- antagonists
- tachykinin
- bronchitis
- cough
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/262,209 US5597845A (en) | 1994-06-20 | 1994-06-20 | Substituted alkyldiamine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL114185A0 true IL114185A0 (xx) | 1995-10-31 |
| IL114185A IL114185A (en) | 1999-07-14 |
Family
ID=22996631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11418595A IL114185A (en) | 1994-06-20 | 1995-06-16 | Substituted alkyldiamine derivatives pharmaceutical compositions containing them and process for their preparation |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5597845A (xx) |
| EP (1) | EP0767783B1 (xx) |
| JP (1) | JP3920916B2 (xx) |
| KR (1) | KR100371981B1 (xx) |
| CN (1) | CN1083429C (xx) |
| AT (1) | ATE169905T1 (xx) |
| AU (1) | AU691619B2 (xx) |
| CA (1) | CA2193348C (xx) |
| DE (1) | DE69504198T2 (xx) |
| DK (1) | DK0767783T3 (xx) |
| ES (1) | ES2121389T3 (xx) |
| FI (1) | FI115135B (xx) |
| HU (1) | HUT75965A (xx) |
| IL (1) | IL114185A (xx) |
| MX (1) | MX9606654A (xx) |
| NO (1) | NO307458B1 (xx) |
| NZ (1) | NZ287291A (xx) |
| TW (1) | TW442451B (xx) |
| WO (1) | WO1995035279A1 (xx) |
| ZA (1) | ZA954947B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW541295B (en) * | 1999-01-05 | 2003-07-11 | Nippon Zoki Pharmaceutical Co | A novel substituted alkylteraamine derivative for use as tachykinin antagonist |
| US7423177B2 (en) | 2001-03-05 | 2008-09-09 | Transtech Pharma, Inc. | Carboxamide derivatives as therapeutic agents |
| US6613801B2 (en) | 2000-05-30 | 2003-09-02 | Transtech Pharma, Inc. | Method for the synthesis of compounds of formula I and their uses thereof |
| AU2002245590B2 (en) | 2001-03-05 | 2006-06-29 | Transtech Pharma, Inc. | Benzimidazole derivatives as therapeutic agents |
| EP2324830A1 (en) | 2002-03-05 | 2011-05-25 | TransTech Pharma Inc. | Process for the preparation of a monocyclic azole derivative that inhibits the interaction of ligands with rage |
| US20090263370A1 (en) * | 2006-11-30 | 2009-10-22 | Guoliang Tao | Methods for treating tachykinin-mediated diseases with cholinesterase |
| TWI517850B (zh) | 2009-09-30 | 2016-01-21 | Ｖｔｖ治療有限責任公司 | 經取代之咪唑衍生物及其使用方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164372A (en) * | 1989-04-28 | 1992-11-17 | Fujisawa Pharmaceutical Company, Ltd. | Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same |
| WO1994004494A1 (en) * | 1992-08-13 | 1994-03-03 | Warner-Lambert Company | Tachykinin antagonists |
| US5472978A (en) * | 1991-07-05 | 1995-12-05 | Merck Sharp & Dohme Ltd. | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
-
1994
- 1994-06-20 US US08/262,209 patent/US5597845A/en not_active Expired - Fee Related
-
1995
- 1995-05-19 WO PCT/US1995/006317 patent/WO1995035279A1/en active IP Right Grant
- 1995-05-19 DK DK95920539T patent/DK0767783T3/da active
- 1995-05-19 MX MX9606654A patent/MX9606654A/es not_active IP Right Cessation
- 1995-05-19 JP JP50217396A patent/JP3920916B2/ja not_active Expired - Fee Related
- 1995-05-19 AU AU25961/95A patent/AU691619B2/en not_active Ceased
- 1995-05-19 CA CA002193348A patent/CA2193348C/en not_active Expired - Fee Related
- 1995-05-19 AT AT95920539T patent/ATE169905T1/de not_active IP Right Cessation
- 1995-05-19 EP EP95920539A patent/EP0767783B1/en not_active Expired - Lifetime
- 1995-05-19 DE DE69504198T patent/DE69504198T2/de not_active Expired - Fee Related
- 1995-05-19 KR KR1019960707303A patent/KR100371981B1/ko not_active IP Right Cessation
- 1995-05-19 NZ NZ287291A patent/NZ287291A/xx unknown
- 1995-05-19 ES ES95920539T patent/ES2121389T3/es not_active Expired - Lifetime
- 1995-05-19 HU HU9603540A patent/HUT75965A/hu not_active Application Discontinuation
- 1995-05-19 CN CN95193680A patent/CN1083429C/zh not_active Expired - Fee Related
- 1995-06-14 ZA ZA954947A patent/ZA954947B/xx unknown
- 1995-06-15 TW TW084106131A patent/TW442451B/zh not_active IP Right Cessation
- 1995-06-16 IL IL11418595A patent/IL114185A/xx not_active IP Right Cessation
-
1996
- 1996-12-18 FI FI965097A patent/FI115135B/fi not_active IP Right Cessation
- 1996-12-19 NO NO965469A patent/NO307458B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ287291A (en) | 1998-10-28 |
| NO965469L (no) | 1997-02-19 |
| IL114185A (en) | 1999-07-14 |
| MX9606654A (es) | 1997-12-31 |
| WO1995035279A1 (en) | 1995-12-28 |
| DE69504198T2 (de) | 1999-04-29 |
| CA2193348C (en) | 1999-08-24 |
| ATE169905T1 (de) | 1998-09-15 |
| JPH10501551A (ja) | 1998-02-10 |
| CA2193348A1 (en) | 1995-12-28 |
| CN1083429C (zh) | 2002-04-24 |
| TW442451B (en) | 2001-06-23 |
| EP0767783B1 (en) | 1998-08-19 |
| HU9603540D0 (en) | 1997-02-28 |
| FI965097A0 (fi) | 1996-12-18 |
| NO965469D0 (no) | 1996-12-19 |
| CN1155883A (zh) | 1997-07-30 |
| NO307458B1 (no) | 2000-04-10 |
| HUT75965A (en) | 1997-05-28 |
| ZA954947B (en) | 1996-01-31 |
| ES2121389T3 (es) | 1998-11-16 |
| AU691619B2 (en) | 1998-05-21 |
| FI115135B (fi) | 2005-03-15 |
| DK0767783T3 (da) | 1999-05-25 |
| FI965097A (fi) | 1996-12-18 |
| AU2596195A (en) | 1996-01-15 |
| JP3920916B2 (ja) | 2007-05-30 |
| EP0767783A1 (en) | 1997-04-16 |
| US5597845A (en) | 1997-01-28 |
| KR100371981B1 (ko) | 2003-06-12 |
| DE69504198D1 (de) | 1998-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9707879A (es) | Derivados de piperazina sustituidos novedosos que tienen actividad antagonista de receptor de taquinina. | |
| PL325339A1 (en) | Derivatives of piperasine as neurokinin antagonists | |
| UA48946C2 (uk) | Арилалкілдіазинони, спосіб їх одержання (варіанти), фармацевтичний склад, спосіб його одержання та спосіб лікування | |
| MY132529A (en) | Paroxetine hydrochloride anhydrate | |
| IL128691A0 (en) | Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants | |
| ZA971183B (en) | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants. | |
| BG102623A (en) | New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous forms | |
| HK1018265A1 (en) | Piperazino derivatives as neurokinin antagonists | |
| MX9708416A (es) | Derivados de piperazino como antagonistas de neuroquininas. | |
| IL114185A0 (xx) | ||
| YU12000A (sh) | Supstituisani 1,2,3,4,5,6-heksahidro-2,6-metano-3-benzazocin -10-oli, postupak za njihovo pripremanje i njihova primena kao lekova | |
| CA2269128A1 (en) | Piperazino derivatives as neurokinin antagonists | |
| CA2275602A1 (en) | Novel carboxy substituted cyclic carboxamide derivatives | |
| MY133169A (en) | Substituted heterocyclic benzocycloalkenes and the use thereof as substances having an analgesic effect | |
| CA2215333A1 (en) | Heterocyclic substituted piperazinone derivatives as tachykinin receptor antagonists | |
| CA2275527A1 (en) | Novel heterocyclic substituted pyrrolidine amide derivatives | |
| DE50006244D1 (en) | Neue substituierte 3-phenoxy- und 3-phenylalkyloxy-2-phenyl-propylamine | |
| CA2329075A1 (en) | Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists | |
| BG105549A (en) | Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system | |
| IT1256925B (it) | Impiego di frammenti o/e di derivati della timosina alfa 1. | |
| MX9703610A (es) | Nuevas (5,6)-heteroaril condensado-pirimidin-4-onas 2,3 disustituidas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |