IL114185A0 - - Google Patents

Info

Publication number
IL114185A0
IL114185A0 IL11418595A IL11418595A IL114185A0 IL 114185 A0 IL114185 A0 IL 114185A0 IL 11418595 A IL11418595 A IL 11418595A IL 11418595 A IL11418595 A IL 11418595A IL 114185 A0 IL114185 A0 IL 114185A0
Authority
IL
Israel
Prior art keywords
useful
antagonists
tachykinin
bronchitis
cough
Prior art date
Application number
IL11418595A
Other languages
English (en)
Other versions
IL114185A (en
Inventor
Dow Pharmaceuticals In Merrell
Original Assignee
Novel Substituted Alkyldiamine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novel Substituted Alkyldiamine filed Critical Novel Substituted Alkyldiamine
Publication of IL114185A0 publication Critical patent/IL114185A0/xx
Publication of IL114185A publication Critical patent/IL114185A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11418595A 1994-06-20 1995-06-16 Substituted alkyldiamine derivatives pharmaceutical compositions containing them and process for their preparation IL114185A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/262,209 US5597845A (en) 1994-06-20 1994-06-20 Substituted alkyldiamine derivatives

Publications (2)

Publication Number Publication Date
IL114185A0 true IL114185A0 (fr) 1995-10-31
IL114185A IL114185A (en) 1999-07-14

Family

ID=22996631

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11418595A IL114185A (en) 1994-06-20 1995-06-16 Substituted alkyldiamine derivatives pharmaceutical compositions containing them and process for their preparation

Country Status (20)

Country Link
US (1) US5597845A (fr)
EP (1) EP0767783B1 (fr)
JP (1) JP3920916B2 (fr)
KR (1) KR100371981B1 (fr)
CN (1) CN1083429C (fr)
AT (1) ATE169905T1 (fr)
AU (1) AU691619B2 (fr)
CA (1) CA2193348C (fr)
DE (1) DE69504198T2 (fr)
DK (1) DK0767783T3 (fr)
ES (1) ES2121389T3 (fr)
FI (1) FI115135B (fr)
HU (1) HUT75965A (fr)
IL (1) IL114185A (fr)
MX (1) MX9606654A (fr)
NO (1) NO307458B1 (fr)
NZ (1) NZ287291A (fr)
TW (1) TW442451B (fr)
WO (1) WO1995035279A1 (fr)
ZA (1) ZA954947B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW541295B (en) * 1999-01-05 2003-07-11 Nippon Zoki Pharmaceutical Co A novel substituted alkylteraamine derivative for use as tachykinin antagonist
US6613801B2 (en) * 2000-05-30 2003-09-02 Transtech Pharma, Inc. Method for the synthesis of compounds of formula I and their uses thereof
AU2002245591B2 (en) 2001-03-05 2007-05-17 Transtech Pharma, Inc. Carboxamide derivatives as therapeutic agents
WO2002069965A1 (fr) 2001-03-05 2002-09-12 Transtech Pharma, Inc. Agents thérapeutiques à base de dérivés benzimidazole
EP1482931B1 (fr) 2002-03-05 2011-10-19 TransTech Pharma, Inc. Derives de l'azole et derives bicycliques fusionnes de l'azole, agents therapeutiques
US20090263370A1 (en) * 2006-11-30 2009-10-22 Guoliang Tao Methods for treating tachykinin-mediated diseases with cholinesterase
EP2470510B1 (fr) 2009-09-30 2014-05-14 TransTech Pharma, LLC Dérivés de l'imidazole substituées four la traitement de da maladie de l'alzheimer.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164372A (en) * 1989-04-28 1992-11-17 Fujisawa Pharmaceutical Company, Ltd. Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
ES2153841T3 (es) * 1992-08-13 2001-03-16 Warner Lambert Co Antagonistas de la taciquinina.

Also Published As

Publication number Publication date
ES2121389T3 (es) 1998-11-16
JP3920916B2 (ja) 2007-05-30
NO965469L (no) 1997-02-19
AU691619B2 (en) 1998-05-21
HUT75965A (en) 1997-05-28
ATE169905T1 (de) 1998-09-15
FI115135B (fi) 2005-03-15
US5597845A (en) 1997-01-28
CA2193348A1 (fr) 1995-12-28
NZ287291A (en) 1998-10-28
NO965469D0 (no) 1996-12-19
EP0767783A1 (fr) 1997-04-16
IL114185A (en) 1999-07-14
ZA954947B (en) 1996-01-31
FI965097A0 (fi) 1996-12-18
WO1995035279A1 (fr) 1995-12-28
DK0767783T3 (da) 1999-05-25
DE69504198D1 (de) 1998-09-24
JPH10501551A (ja) 1998-02-10
FI965097A (fi) 1996-12-18
MX9606654A (es) 1997-12-31
DE69504198T2 (de) 1999-04-29
EP0767783B1 (fr) 1998-08-19
AU2596195A (en) 1996-01-15
TW442451B (en) 2001-06-23
CA2193348C (fr) 1999-08-24
CN1155883A (zh) 1997-07-30
NO307458B1 (no) 2000-04-10
HU9603540D0 (en) 1997-02-28
CN1083429C (zh) 2002-04-24
KR100371981B1 (ko) 2003-06-12

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Legal Events

Date Code Title Description
FF Patent granted
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees