IL111963A0 - Platelet activating factor antagonists: imidazopyridine indoles - Google Patents

Platelet activating factor antagonists: imidazopyridine indoles

Info

Publication number
IL111963A0
IL111963A0 IL11196394A IL11196394A IL111963A0 IL 111963 A0 IL111963 A0 IL 111963A0 IL 11196394 A IL11196394 A IL 11196394A IL 11196394 A IL11196394 A IL 11196394A IL 111963 A0 IL111963 A0 IL 111963A0
Authority
IL
Israel
Prior art keywords
imidazopyridine
indoles
activating factor
platelet activating
paf
Prior art date
Application number
IL11196394A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL111963A0 publication Critical patent/IL111963A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11196394A 1993-12-16 1994-12-12 Platelet activating factor antagonists: imidazopyridine indoles IL111963A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16856493A 1993-12-16 1993-12-16
US32463194A 1994-10-18 1994-10-18
US08/347,528 US5486525A (en) 1993-12-16 1994-12-05 Platelet activating factor antagonists: imidazopyridine indoles

Publications (1)

Publication Number Publication Date
IL111963A0 true IL111963A0 (en) 1995-03-15

Family

ID=27389538

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11196394A IL111963A0 (en) 1993-12-16 1994-12-12 Platelet activating factor antagonists: imidazopyridine indoles

Country Status (13)

Country Link
US (1) US5486525A (de)
EP (1) EP0734386B1 (de)
JP (1) JPH09507474A (de)
KR (1) KR960706494A (de)
AT (1) ATE212992T1 (de)
AU (1) AU690620B2 (de)
CA (1) CA2176247A1 (de)
DE (1) DE69429827T2 (de)
DK (1) DK0734386T3 (de)
ES (1) ES2173171T3 (de)
IL (1) IL111963A0 (de)
PT (1) PT734386E (de)
WO (1) WO1995016687A1 (de)

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US5753664A (en) * 1995-03-16 1998-05-19 Takeda Chemical Industries, Ltd. Heterocyclic compounds, their production and use
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
US5633388A (en) * 1996-03-29 1997-05-27 Viropharma Incorporated Compounds, compositions and methods for treatment of hepatitis C
US6630496B1 (en) 1996-08-26 2003-10-07 Genetics Institute Llc Inhibitors of phospholipase enzymes
AU4400597A (en) * 1996-10-08 1998-05-05 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
US5811425A (en) * 1997-03-04 1998-09-22 Abbott Laboratories Heterocyclic compounds as COX-2 inhibitors
US6916841B2 (en) * 1998-02-25 2005-07-12 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6828344B1 (en) 1998-02-25 2004-12-07 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6500853B1 (en) 1998-02-28 2002-12-31 Genetics Institute, Llc Inhibitors of phospholipase enzymes
TW526202B (en) * 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
US6534535B1 (en) 1999-08-12 2003-03-18 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
AU7962200A (en) * 1999-10-29 2001-05-14 Wakunaga Pharmaceutical Co., Ltd Novel indole derivatives and drugs containing the same as the active ingredient
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
US7507767B2 (en) * 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
RU2004117907A (ru) * 2001-11-14 2006-01-10 Шеринг Корпорейшн (US) Лиганды каннабиноидных рецепторов
TWI317634B (en) * 2001-12-13 2009-12-01 Nat Health Research Institutes Aroyl indoles compounds
US7528165B2 (en) * 2001-12-13 2009-05-05 National Health Research Institutes Indole compounds
US7632955B2 (en) * 2001-12-13 2009-12-15 National Health Research Institutes Indole compounds
CN100503608C (zh) * 2002-01-07 2009-06-24 卫材R&D管理株式会社 脱氮嘌呤及其用途
TW200307542A (en) * 2002-05-30 2003-12-16 Astrazeneca Ab Novel compounds
SE0201635D0 (sv) * 2002-05-30 2002-05-30 Astrazeneca Ab Novel compounds
ATE388937T1 (de) 2002-06-19 2008-03-15 Schering Corp Agonisten des cannabinoidrezeptors
US6906096B2 (en) * 2002-06-28 2005-06-14 Irm Llc 4,7-Disubstituted indoles and methods of making
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
SE0202241D0 (sv) * 2002-07-17 2002-07-17 Astrazeneca Ab Novel Compounds
TW200505902A (en) * 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
SE0301569D0 (sv) * 2003-05-27 2003-05-27 Astrazeneca Ab Novel compounds
SE0302232D0 (sv) * 2003-08-18 2003-08-18 Astrazeneca Ab Novel Compounds
JP2007508363A (ja) * 2003-10-14 2007-04-05 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
SE0303180D0 (sv) * 2003-11-26 2003-11-26 Astrazeneca Ab Novel compounds
CA2549606C (en) * 2003-12-22 2015-10-06 K.U. Leuven Research & Development Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
WO2006033703A1 (en) * 2004-07-27 2006-03-30 Gilead Sciences, Inc. Imidazo[4,5-d]pyrimidines, their uses and methods of preparation
CA2592388C (en) * 2004-12-21 2013-04-02 Steven S. Bondy Imidazo[4,5-c]pyridine compound and method of antiviral treatment
US7456289B2 (en) * 2004-12-31 2008-11-25 National Health Research Institutes Anti-tumor compounds
GB0500604D0 (en) * 2005-01-13 2005-02-16 Astrazeneca Ab Novel process
ATE518860T1 (de) * 2005-06-22 2011-08-15 Plexxikon Inc Pyrroloä2,3-büpyridinderivate als proteinkinaseinhibitoren
CN101370775A (zh) 2006-01-13 2009-02-18 惠氏公司 作为5-羟基色胺受体配体的经磺酰基取代1h-吲哚
CN101454284A (zh) * 2006-05-26 2009-06-10 阿斯利康(瑞典)有限公司 联芳基或芳基-杂芳基取代的吲哚类化合物
SG175604A1 (en) * 2006-07-07 2011-11-28 Gilead Sciences Inc Novel pyridazine compound and use thereof
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
PE20121126A1 (es) * 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
WO2008079909A1 (en) * 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
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US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
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TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
EP2714680B1 (de) 2011-05-27 2015-11-25 Amira Pharmaceuticals, Inc. Heterocyclische autotaxin-inhibitoren und ihre verwendungen
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US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
RU2657540C2 (ru) 2012-06-26 2018-06-14 Янссен Фармацевтика Нв Комбинации, содержащие ингибиторы pde 2, такие как 1-арил-4-метил-[1,2,4]триазоло[4,3-а]хиноксалиновые соединения, и ингибиторы pde 10, для применения в лечении неврологических или метаболических расстройств
BR112015000459B1 (pt) 2012-07-09 2022-02-08 Janssen Pharmaceutica N.V. Inibidores da enzima fosfodiesterase 10, seu uso, composição farmacêutica que os compreende, seus processo de preparação e produto
JP2016145155A (ja) * 2013-04-30 2016-08-12 日本農薬株式会社 フタルアミド誘導体及び該誘導体を含有する農園芸用殺虫剤並びにその使用方法
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CH574441A5 (de) * 1973-06-14 1976-04-15 Ciba Geigy Ag
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US5120749A (en) * 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
US5459152A (en) * 1991-07-17 1995-10-17 Abbott Laboratories Platelet activating factor antagonists

Also Published As

Publication number Publication date
CA2176247A1 (en) 1995-06-22
KR960706494A (ko) 1996-12-09
AU1303695A (en) 1995-07-03
EP0734386A1 (de) 1996-10-02
ES2173171T3 (es) 2002-10-16
DE69429827T2 (de) 2002-11-21
JPH09507474A (ja) 1997-07-29
AU690620B2 (en) 1998-04-30
ATE212992T1 (de) 2002-02-15
PT734386E (pt) 2002-07-31
DK0734386T3 (da) 2002-05-27
US5486525A (en) 1996-01-23
WO1995016687A1 (en) 1995-06-22
DE69429827D1 (de) 2002-03-21
EP0734386B1 (de) 2002-02-06

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