IL111831A - Method of detecting the presence of a nucleic acid in a sample - Google Patents
Method of detecting the presence of a nucleic acid in a sampleInfo
- Publication number
- IL111831A IL111831A IL11183194A IL11183194A IL111831A IL 111831 A IL111831 A IL 111831A IL 11183194 A IL11183194 A IL 11183194A IL 11183194 A IL11183194 A IL 11183194A IL 111831 A IL111831 A IL 111831A
- Authority
- IL
- Israel
- Prior art keywords
- nucleic acid
- sample
- detecting
- product
- nuclease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C07K14/003—Peptide-nucleic acids (PNAs)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9324955A GB2285445A (en) | 1993-12-06 | 1993-12-06 | Protecting nucleic acids and methods of analysis |
Publications (2)
Publication Number | Publication Date |
---|---|
IL111831A0 IL111831A0 (en) | 1995-01-24 |
IL111831A true IL111831A (en) | 2000-12-06 |
Family
ID=10746180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11183194A IL111831A (en) | 1993-12-06 | 1994-11-30 | Method of detecting the presence of a nucleic acid in a sample |
Country Status (16)
Country | Link |
---|---|
US (1) | US5861250A (xx) |
EP (1) | EP0733062B1 (xx) |
JP (1) | JPH09506255A (xx) |
KR (1) | KR100221399B1 (xx) |
AT (1) | ATE166066T1 (xx) |
AU (1) | AU682563B2 (xx) |
CA (1) | CA2177603C (xx) |
DE (1) | DE69410291T2 (xx) |
DK (1) | DK0733062T3 (xx) |
ES (1) | ES2119370T3 (xx) |
FI (1) | FI111266B (xx) |
GB (1) | GB2285445A (xx) |
IL (1) | IL111831A (xx) |
NO (1) | NO317934B1 (xx) |
WO (1) | WO1995015974A1 (xx) |
ZA (1) | ZA949643B (xx) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0815259T3 (da) | 1995-03-04 | 2001-09-17 | Pna Diagnostics As | Modulation af nucleinsyre-bindingspartneres bindingsegenskaber |
WO1996014341A1 (en) * | 1995-06-22 | 1996-05-17 | Dako A/S | Monoclonal antibody capable of binding to pna/nucleic acid complexes |
JPH11511642A (ja) * | 1995-06-22 | 1999-10-12 | ダコ アクティーゼルスカブ | Pna/核酸複合体に結合し得る組換え抗体 |
US5677124A (en) * | 1996-07-03 | 1997-10-14 | Ambion, Inc. | Ribonuclease resistant viral RNA standards |
US5939262A (en) | 1996-07-03 | 1999-08-17 | Ambion, Inc. | Ribonuclease resistant RNA preparation and utilization |
US5853990A (en) | 1996-07-26 | 1998-12-29 | Edward E. Winger | Real time homogeneous nucleotide assay |
DE19633436A1 (de) | 1996-08-20 | 1998-02-26 | Boehringer Mannheim Gmbh | Verfahren zum Nachweis von Nukleinsäuren unter Ermittlung der Masse |
US6617422B1 (en) | 1997-05-23 | 2003-09-09 | Peter Nielsen | Peptide nucleic acid monomers and oligomers |
WO1999034014A2 (en) * | 1997-12-23 | 1999-07-08 | Roche Diagnostics Gmbh | A method for the determination of a nucleic acid |
JP2002517981A (ja) * | 1998-01-13 | 2002-06-25 | ビオヒプ テヒノロギース ゲゼルシャフト ミット ベシュレンクテル ハフツング | 核酸配列を検出するための方法 |
US6441152B1 (en) | 1998-12-08 | 2002-08-27 | Boston Probes, Inc. | Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices |
EP1137807B1 (en) * | 1998-12-08 | 2004-09-08 | Boston Probes, Inc. | Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices |
WO2000056937A2 (en) | 1999-03-25 | 2000-09-28 | Hyseq, Inc. | Solution-based methods and materials for sequence analysis by hybridization |
US7816098B2 (en) * | 2000-01-31 | 2010-10-19 | Sense Proteomic Limited | Methods of making and using a protein array |
GB2373500B (en) * | 2000-02-04 | 2004-12-15 | Aeomica Inc | Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence |
US6962906B2 (en) * | 2000-03-14 | 2005-11-08 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
US20040014644A1 (en) * | 2000-03-14 | 2004-01-22 | Vladimir Efimov | Oligonucleotide analogues and methods of use for modulating gene expression |
CA2402319A1 (en) | 2000-03-14 | 2001-09-20 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
GB0406864D0 (en) | 2004-03-26 | 2004-04-28 | Qiagen As | Nucleic acid sequencing |
US20080268451A1 (en) * | 2007-03-30 | 2008-10-30 | Bruce Seligmann | Measurement of an insoluble analyte in a sample |
US20100129902A1 (en) | 2008-11-24 | 2010-05-27 | Erhard Ralf Schoenbrunner | Replication Stable and RNase Resistant Chimeras of Pestivirus with Insertion in 3' Nontranslated Region (3'NTR) |
CA2778249C (en) * | 2009-11-03 | 2018-12-04 | Htg Molecular Diagnostics, Inc. | Quantitative nuclease protection sequencing (qnps) |
CN103649335B (zh) | 2011-05-04 | 2015-11-25 | Htg分子诊断有限公司 | 定量核酸酶保护测定(qnpa)和测序(qnps)的改进 |
KR20160106684A (ko) | 2014-01-10 | 2016-09-12 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | 히드록시포름아미드 유도체 및 그의 용도 |
US10689689B2 (en) * | 2015-12-28 | 2020-06-23 | Roche Molecular Systems, Inc. | Generic method for the stabilization of specific RNA |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US5578468A (en) * | 1987-08-10 | 1996-11-26 | Duke University | Site-specific RNA cleavage |
DK51092D0 (da) * | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
US5539082A (en) * | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
-
1993
- 1993-12-06 GB GB9324955A patent/GB2285445A/en not_active Withdrawn
-
1994
- 1994-11-30 DE DE69410291T patent/DE69410291T2/de not_active Expired - Lifetime
- 1994-11-30 EP EP95903782A patent/EP0733062B1/en not_active Expired - Lifetime
- 1994-11-30 CA CA002177603A patent/CA2177603C/en not_active Expired - Lifetime
- 1994-11-30 IL IL11183194A patent/IL111831A/xx not_active IP Right Cessation
- 1994-11-30 AU AU12729/95A patent/AU682563B2/en not_active Expired
- 1994-11-30 WO PCT/EP1994/003973 patent/WO1995015974A1/en active IP Right Grant
- 1994-11-30 DK DK95903782T patent/DK0733062T3/da active
- 1994-11-30 AT AT95903782T patent/ATE166066T1/de not_active IP Right Cessation
- 1994-11-30 ES ES95903782T patent/ES2119370T3/es not_active Expired - Lifetime
- 1994-11-30 JP JP7515942A patent/JPH09506255A/ja active Pending
- 1994-11-30 KR KR1019960703043A patent/KR100221399B1/ko not_active IP Right Cessation
- 1994-12-05 ZA ZA949643A patent/ZA949643B/xx unknown
-
1996
- 1996-06-05 FI FI962340A patent/FI111266B/fi not_active IP Right Cessation
- 1996-06-05 NO NO19962331A patent/NO317934B1/no not_active IP Right Cessation
- 1996-06-06 US US08/659,529 patent/US5861250A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0733062A1 (en) | 1996-09-25 |
NO317934B1 (no) | 2005-01-10 |
ES2119370T3 (es) | 1998-10-01 |
CA2177603A1 (en) | 1995-06-15 |
FI962340A (fi) | 1996-06-05 |
FI111266B (fi) | 2003-06-30 |
JPH09506255A (ja) | 1997-06-24 |
ZA949643B (en) | 1996-06-05 |
NO962331L (no) | 1996-08-06 |
ATE166066T1 (de) | 1998-05-15 |
DE69410291T2 (de) | 1998-10-29 |
EP0733062B1 (en) | 1998-05-13 |
AU682563B2 (en) | 1997-10-09 |
DE69410291D1 (de) | 1998-06-18 |
KR960706504A (ko) | 1996-12-09 |
FI962340A0 (fi) | 1996-06-05 |
WO1995015974A1 (en) | 1995-06-15 |
NO962331D0 (no) | 1996-06-05 |
US5861250A (en) | 1999-01-19 |
IL111831A0 (en) | 1995-01-24 |
DK0733062T3 (da) | 1999-03-15 |
KR100221399B1 (ko) | 1999-10-01 |
GB9324955D0 (en) | 1994-01-26 |
AU1272995A (en) | 1995-06-27 |
CA2177603C (en) | 2000-07-18 |
GB2285445A (en) | 1995-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |