IL111725A - תולדות '3-אזירידינו-אנתראציקלין, הכנתן ותכשירי רוקחות המכילים אותן - Google Patents
תולדות '3-אזירידינו-אנתראציקלין, הכנתן ותכשירי רוקחות המכילים אותןInfo
- Publication number
- IL111725A IL111725A IL11172594A IL11172594A IL111725A IL 111725 A IL111725 A IL 111725A IL 11172594 A IL11172594 A IL 11172594A IL 11172594 A IL11172594 A IL 11172594A IL 111725 A IL111725 A IL 111725A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- group
- deamino
- anthracycline glycoside
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939325417A GB9325417D0 (en) | 1993-12-13 | 1993-12-13 | 3'- aziridino-anthracycline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL111725A0 IL111725A0 (en) | 1995-01-24 |
| IL111725A true IL111725A (he) | 1998-07-15 |
Family
ID=10746494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11172594A IL111725A (he) | 1993-12-13 | 1994-11-22 | תולדות '3-אזירידינו-אנתראציקלין, הכנתן ותכשירי רוקחות המכילים אותן |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5532218A (he) |
| EP (1) | EP0683788B1 (he) |
| JP (1) | JPH08506835A (he) |
| KR (1) | KR100352734B1 (he) |
| CN (1) | CN1039123C (he) |
| AT (1) | ATE157369T1 (he) |
| AU (1) | AU676625B2 (he) |
| CA (1) | CA2154890A1 (he) |
| DE (1) | DE69405214T2 (he) |
| DK (1) | DK0683788T3 (he) |
| ES (1) | ES2107294T3 (he) |
| FI (1) | FI108036B (he) |
| GB (1) | GB9325417D0 (he) |
| GR (1) | GR3025266T3 (he) |
| HK (1) | HK1011692A1 (he) |
| HU (1) | HU217630B (he) |
| IL (1) | IL111725A (he) |
| MY (1) | MY117086A (he) |
| NO (1) | NO304951B1 (he) |
| NZ (1) | NZ276401A (he) |
| PL (1) | PL178806B1 (he) |
| RU (1) | RU2149163C1 (he) |
| TW (1) | TW336235B (he) |
| UA (1) | UA43839C2 (he) |
| WO (1) | WO1995016695A2 (he) |
| ZA (1) | ZA949701B (he) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5948896A (en) * | 1997-08-13 | 1999-09-07 | Gem Pharmaceuticals | Processes for preparing 13-deoxy anthracycline derivatives |
| US5942605A (en) * | 1998-03-03 | 1999-08-24 | Gem Pharmaceuticals, Inc. | 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them |
| GB9806324D0 (en) * | 1998-03-24 | 1998-05-20 | Pharmacia & Upjohn Spa | Antitumour synergetic composition |
| GB9808027D0 (en) * | 1998-04-15 | 1998-06-17 | Pharmacia & Upjohn Spa | 13-dihydro-3' aziridino anthracyclines |
| GB9904387D0 (en) * | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
| GB9904386D0 (en) | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
| GB0006601D0 (en) * | 2000-03-17 | 2000-05-10 | Pharmacia & Upjohn Spa | Crystalline alkycycline derivative |
| GB0117403D0 (en) * | 2001-07-17 | 2001-09-05 | Pharmacia & Upjohn Spa | Solvent-free crystalline anthracycline derivatives |
| CN101237771B (zh) * | 2005-05-12 | 2013-03-20 | 俄亥俄州立大学研究基金会 | 多重耐药抗癌药蒽环类 |
| WO2009124468A1 (zh) * | 2008-04-11 | 2009-10-15 | 天津和美生物技术有限公司 | 具有高活性的四环蒽醌类抗生素的衍生物及其制备和应用 |
| CN101912600B (zh) * | 2010-01-11 | 2014-01-29 | 杨国汉 | 改善胰岛素在溶液中稳定性的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54141759A (en) * | 1978-04-24 | 1979-11-05 | Microbial Chem Res Found | Novel anthracycline derivative |
| GB8614323D0 (en) * | 1986-06-12 | 1986-07-16 | Erba Farmitalia | Anthracyclines |
| US5413992A (en) * | 1992-07-31 | 1995-05-09 | The Scripps Research Institute | Daunomycin derivative with reduced cytotoxicity toward normal cells |
-
1993
- 1993-12-13 GB GB939325417A patent/GB9325417D0/en active Pending
-
1994
- 1994-11-21 DK DK95901401.0T patent/DK0683788T3/da active
- 1994-11-21 NZ NZ276401A patent/NZ276401A/en unknown
- 1994-11-21 HU HU9502662A patent/HU217630B/hu not_active IP Right Cessation
- 1994-11-21 JP JP7516486A patent/JPH08506835A/ja not_active Ceased
- 1994-11-21 CA CA002154890A patent/CA2154890A1/en not_active Abandoned
- 1994-11-21 DE DE69405214T patent/DE69405214T2/de not_active Expired - Fee Related
- 1994-11-21 CN CN94191153A patent/CN1039123C/zh not_active Expired - Fee Related
- 1994-11-21 AU AU10660/95A patent/AU676625B2/en not_active Ceased
- 1994-11-21 AT AT95901401T patent/ATE157369T1/de not_active IP Right Cessation
- 1994-11-21 RU RU95120191A patent/RU2149163C1/ru not_active IP Right Cessation
- 1994-11-21 ES ES95901401T patent/ES2107294T3/es not_active Expired - Lifetime
- 1994-11-21 WO PCT/EP1994/003840 patent/WO1995016695A2/en active IP Right Grant
- 1994-11-21 UA UA95083705A patent/UA43839C2/uk unknown
- 1994-11-21 US US08/345,450 patent/US5532218A/en not_active Expired - Fee Related
- 1994-11-21 KR KR1019950703348A patent/KR100352734B1/ko not_active IP Right Cessation
- 1994-11-21 PL PL94310177A patent/PL178806B1/pl not_active IP Right Cessation
- 1994-11-21 EP EP95901401A patent/EP0683788B1/en not_active Expired - Lifetime
- 1994-11-22 IL IL11172594A patent/IL111725A/he not_active IP Right Cessation
- 1994-11-23 MY MYPI94003127A patent/MY117086A/en unknown
- 1994-11-30 TW TW083111129A patent/TW336235B/zh active
- 1994-12-06 ZA ZA949701A patent/ZA949701B/xx unknown
-
1995
- 1995-08-09 FI FI953784A patent/FI108036B/fi not_active IP Right Cessation
- 1995-08-11 NO NO953163A patent/NO304951B1/no not_active IP Right Cessation
-
1997
- 1997-11-05 GR GR970402904T patent/GR3025266T3/el unknown
-
1998
- 1998-12-03 HK HK98112738A patent/HK1011692A1/xx not_active IP Right Cessation
Also Published As
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| AU632102B2 (en) | New 3'-(4-morpholinyl)- and 3'-(2-methoxy-4-morpholinyl)- anthracycline derivatives | |
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| CH676985A5 (he) | ||
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| KR0157612B1 (ko) | 신규 안트라사이클린 글리코사이드 유도체 | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |