IL110553A - Process for the preparation of 9-amino camptothecin from the 12-nitro derivative, pharmaceutical compositions containing it and certain intermediates - Google Patents
Process for the preparation of 9-amino camptothecin from the 12-nitro derivative, pharmaceutical compositions containing it and certain intermediatesInfo
- Publication number
- IL110553A IL110553A IL110553A IL11055394A IL110553A IL 110553 A IL110553 A IL 110553A IL 110553 A IL110553 A IL 110553A IL 11055394 A IL11055394 A IL 11055394A IL 110553 A IL110553 A IL 110553A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- compound
- amino camptothecin
- obtaining
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939316352A GB9316352D0 (en) | 1993-08-06 | 1993-08-06 | Process for the preparation of 9-amino camptothecin |
Publications (2)
Publication Number | Publication Date |
---|---|
IL110553A0 IL110553A0 (en) | 1994-11-11 |
IL110553A true IL110553A (en) | 1997-03-18 |
Family
ID=10740090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL110553A IL110553A (en) | 1993-08-06 | 1994-08-03 | Process for the preparation of 9-amino camptothecin from the 12-nitro derivative, pharmaceutical compositions containing it and certain intermediates |
Country Status (15)
Country | Link |
---|---|
US (1) | US6403603B1 (zh) |
EP (1) | EP0663914A1 (zh) |
JP (2) | JP3556223B2 (zh) |
KR (1) | KR950703565A (zh) |
CN (1) | CN1048296C (zh) |
AU (1) | AU678587B2 (zh) |
CA (1) | CA2145514C (zh) |
FI (1) | FI951581A (zh) |
GB (1) | GB9316352D0 (zh) |
HU (1) | HUT71240A (zh) |
IL (1) | IL110553A (zh) |
RU (1) | RU2145325C1 (zh) |
TW (1) | TW269691B (zh) |
WO (1) | WO1995004736A1 (zh) |
ZA (1) | ZA945878B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9319944D0 (en) * | 1993-09-28 | 1993-11-17 | Erba Carlo Spa | Process for the preparation of 9-amino camptothecin |
GB9410388D0 (en) * | 1994-05-24 | 1994-07-13 | Erba Carlo Spa | Method for the preparation of 9-amino camptothecin |
CN1324032C (zh) * | 2004-01-07 | 2007-07-04 | 重庆医药工业研究院有限责任公司 | 一种新的9-硝基喜树碱晶型和药物组合物 |
CN1312155C (zh) * | 2005-01-21 | 2007-04-25 | 华东理工大学 | 一种分离纯化9-硝基喜树碱的方法 |
CN102731516B (zh) * | 2011-04-07 | 2014-07-02 | 宁波天衡药业股份有限公司 | 一类具有抗肿瘤活性的喜树碱衍生物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2150234A1 (de) * | 1971-10-08 | 1973-04-12 | Basf Ag | Verfahren zur herstellung von camptothecin und camptothecin-derivaten |
US4894456A (en) * | 1987-03-31 | 1990-01-16 | Research Triangle Institute | Synthesis of camptothecin and analogs thereof |
US5180722A (en) * | 1987-04-14 | 1993-01-19 | Research Triangle Institute | 10,11-methylenedioxy-20(RS)-camptothecin and 10,11-methylenedioxy-20(S)-camptothecin analogs |
US5225404A (en) * | 1989-11-06 | 1993-07-06 | New York University | Methods of treating colon tumors with tumor-inhibiting camptothecin compounds |
DE4134885C2 (de) * | 1991-10-23 | 1994-04-07 | Praezisions Ventil Gmbh | Betätigungsaufsatz für einen Sprühbehälter |
-
1993
- 1993-08-06 GB GB939316352A patent/GB9316352D0/en active Pending
-
1994
- 1994-07-18 CA CA002145514A patent/CA2145514C/en not_active Expired - Fee Related
- 1994-07-18 KR KR1019950701312A patent/KR950703565A/ko not_active Application Discontinuation
- 1994-07-18 AU AU72290/94A patent/AU678587B2/en not_active Ceased
- 1994-07-18 JP JP50617895A patent/JP3556223B2/ja not_active Expired - Fee Related
- 1994-07-18 HU HU9501319A patent/HUT71240A/hu unknown
- 1994-07-18 RU RU95112573A patent/RU2145325C1/ru active
- 1994-07-18 EP EP94921656A patent/EP0663914A1/en not_active Withdrawn
- 1994-07-18 WO PCT/EP1994/002370 patent/WO1995004736A1/en not_active Application Discontinuation
- 1994-07-18 CN CN94190581A patent/CN1048296C/zh not_active Expired - Fee Related
- 1994-08-02 US US08/284,129 patent/US6403603B1/en not_active Expired - Fee Related
- 1994-08-03 IL IL110553A patent/IL110553A/xx not_active IP Right Cessation
- 1994-08-03 TW TW083107096A patent/TW269691B/zh active
- 1994-08-05 ZA ZA945878A patent/ZA945878B/xx unknown
-
1995
- 1995-04-03 FI FI951581A patent/FI951581A/fi unknown
-
2004
- 2004-03-01 JP JP2004055749A patent/JP2004217665A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
FI951581A0 (fi) | 1995-04-03 |
AU678587B2 (en) | 1997-06-05 |
US6403603B1 (en) | 2002-06-11 |
HUT71240A (en) | 1995-11-28 |
KR950703565A (ko) | 1995-09-20 |
FI951581A (fi) | 1995-04-03 |
JP2004217665A (ja) | 2004-08-05 |
IL110553A0 (en) | 1994-11-11 |
CA2145514C (en) | 2006-06-06 |
CN1113384A (zh) | 1995-12-13 |
RU95112573A (ru) | 1997-02-20 |
ZA945878B (en) | 1995-03-10 |
WO1995004736A1 (en) | 1995-02-16 |
GB9316352D0 (en) | 1993-09-22 |
CA2145514A1 (en) | 1995-02-16 |
TW269691B (zh) | 1996-02-01 |
CN1048296C (zh) | 2000-01-12 |
JP3556223B2 (ja) | 2004-08-18 |
RU2145325C1 (ru) | 2000-02-10 |
JPH08506597A (ja) | 1996-07-16 |
AU7229094A (en) | 1995-02-28 |
EP0663914A1 (en) | 1995-07-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |