IL109530A - Heterocyclically substituted 1, 2, 4 9 triazolo 4, 3-a9 quinoxaline-1, 4-dione derivatives pharmaceutical compositions containing them and method for their preparation - Google Patents
Heterocyclically substituted 1, 2, 4 9 triazolo 4, 3-a9 quinoxaline-1, 4-dione derivatives pharmaceutical compositions containing them and method for their preparationInfo
- Publication number
- IL109530A IL109530A IL10953094A IL10953094A IL109530A IL 109530 A IL109530 A IL 109530A IL 10953094 A IL10953094 A IL 10953094A IL 10953094 A IL10953094 A IL 10953094A IL 109530 A IL109530 A IL 109530A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- triazolo
- quinoxaline
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK53593A DK53593D0 (da) | 1993-05-06 | 1993-05-06 | Oe1,2,4aatriazolooe4,3-aaaquinoxalinonforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse |
| DK128793A DK128793D0 (es) | 1993-11-12 | 1993-11-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL109530A0 IL109530A0 (en) | 1994-08-26 |
| IL109530A true IL109530A (en) | 1997-01-10 |
Family
ID=26064177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10953094A IL109530A (en) | 1993-05-06 | 1994-05-03 | Heterocyclically substituted 1, 2, 4 9 triazolo 4, 3-a9 quinoxaline-1, 4-dione derivatives pharmaceutical compositions containing them and method for their preparation |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5532236A (es) |
| EP (1) | EP0698024B1 (es) |
| JP (1) | JPH08509747A (es) |
| KR (1) | KR100304177B1 (es) |
| CN (1) | CN1041931C (es) |
| AT (1) | ATE148120T1 (es) |
| AU (1) | AU683062B2 (es) |
| CA (1) | CA2162023A1 (es) |
| DE (1) | DE69401583T2 (es) |
| DK (1) | DK0698024T3 (es) |
| ES (1) | ES2097652T3 (es) |
| FI (1) | FI955304A (es) |
| GR (1) | GR3023001T3 (es) |
| HU (1) | HUT73983A (es) |
| IL (1) | IL109530A (es) |
| NO (1) | NO305516B1 (es) |
| NZ (1) | NZ266127A (es) |
| TW (1) | TW377354B (es) |
| WO (1) | WO1994026746A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE190616T1 (de) * | 1994-09-16 | 2000-04-15 | Novo Nordisk As | (1,2,4)triazolo(4,3-a)chinoxylinonderivate, ihre darstellung und verwendung als antagonisten von ampa-rezeptoren |
| JPH10506620A (ja) * | 1994-09-16 | 1998-06-30 | ノボ ノルディスク アクティーゼルスカブ | 〔１，２，４〕トリアゾロ〔４，３−ａ〕キノキサリノン誘導体、それらの調製方法及び使用 |
| DE19510965A1 (de) * | 1995-03-24 | 1996-09-26 | Asta Medica Ag | Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung |
| KR100375155B1 (ko) | 1996-05-15 | 2003-08-19 | 화이자 인코포레이티드 | 신규한2,3-이치환된-4(3에이치)-퀴나졸리논 |
| US6063774A (en) * | 1996-12-16 | 2000-05-16 | Warner-Lambert Company | Tricyclic quinoxaline derivatives as neuroprotective agents |
| US6015800A (en) * | 1997-09-03 | 2000-01-18 | Warner-Lambert Company | Substituted quinoxaline-2-ones as glutamate receptor antagonists |
| US6323208B1 (en) | 1997-09-05 | 2001-11-27 | Pfizer Inc | Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones |
| IL125950A0 (en) * | 1997-09-05 | 1999-04-11 | Pfizer Prod Inc | Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy |
| WO1999024434A1 (en) | 1997-11-11 | 1999-05-20 | Ono Pharmaceutical Co., Ltd. | Fused pyrazine compounds |
| US20040152694A1 (en) * | 2003-02-04 | 2004-08-05 | Istvan Kurucz | Methods and compositions for treating inflammatory disorders of the airways |
| US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| EP2338492A1 (en) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
| WO2016199943A1 (en) * | 2015-06-11 | 2016-12-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds |
| MX2021000762A (es) * | 2018-07-20 | 2021-03-29 | Gruenenthal Gmbh | Derivados de triazoloquinoxalina sustituida. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4400382A (en) * | 1980-05-09 | 1983-08-23 | Usv Pharmaceutical Corporation | Thiazoloquinoxalin-1,4-diones for treating allergy |
| DK162491D0 (da) * | 1991-09-20 | 1991-09-20 | Novo Nordisk As | Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne |
-
1994
- 1994-04-28 WO PCT/DK1994/000170 patent/WO1994026746A1/en active IP Right Grant
- 1994-04-28 NZ NZ266127A patent/NZ266127A/en unknown
- 1994-04-28 CA CA002162023A patent/CA2162023A1/en not_active Abandoned
- 1994-04-28 EP EP94915514A patent/EP0698024B1/en not_active Expired - Lifetime
- 1994-04-28 DK DK94915514.7T patent/DK0698024T3/da active
- 1994-04-28 ES ES94915514T patent/ES2097652T3/es not_active Expired - Lifetime
- 1994-04-28 CN CN94192501A patent/CN1041931C/zh not_active Expired - Fee Related
- 1994-04-28 JP JP6524834A patent/JPH08509747A/ja not_active Ceased
- 1994-04-28 KR KR1019950704895A patent/KR100304177B1/ko not_active IP Right Cessation
- 1994-04-28 AT AT94915514T patent/ATE148120T1/de not_active IP Right Cessation
- 1994-04-28 DE DE69401583T patent/DE69401583T2/de not_active Expired - Fee Related
- 1994-04-28 HU HU9503157A patent/HUT73983A/hu unknown
- 1994-04-28 AU AU67200/94A patent/AU683062B2/en not_active Ceased
- 1994-05-03 US US08/237,518 patent/US5532236A/en not_active Expired - Fee Related
- 1994-05-03 IL IL10953094A patent/IL109530A/xx not_active IP Right Cessation
- 1994-05-04 TW TW083104020A patent/TW377354B/zh active
-
1995
- 1995-11-03 NO NO954402A patent/NO305516B1/no not_active IP Right Cessation
- 1995-11-06 FI FI955304A patent/FI955304A/fi unknown
-
1997
- 1997-04-01 GR GR970400675T patent/GR3023001T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0698024A1 (en) | 1996-02-28 |
| TW377354B (en) | 1999-12-21 |
| DE69401583T2 (de) | 1997-06-12 |
| JPH08509747A (ja) | 1996-10-15 |
| AU683062B2 (en) | 1997-10-30 |
| NZ266127A (en) | 1997-11-24 |
| KR960701877A (ko) | 1996-03-28 |
| CN1125446A (zh) | 1996-06-26 |
| HUT73983A (en) | 1996-10-28 |
| ATE148120T1 (de) | 1997-02-15 |
| ES2097652T3 (es) | 1997-04-01 |
| IL109530A0 (en) | 1994-08-26 |
| NO305516B1 (no) | 1999-06-14 |
| GR3023001T3 (en) | 1997-07-30 |
| WO1994026746A1 (en) | 1994-11-24 |
| CA2162023A1 (en) | 1994-11-24 |
| US5532236A (en) | 1996-07-02 |
| DK0698024T3 (da) | 1997-07-28 |
| CN1041931C (zh) | 1999-02-03 |
| NO954402D0 (no) | 1995-11-03 |
| HU9503157D0 (en) | 1996-01-29 |
| AU6720094A (en) | 1994-12-12 |
| FI955304A0 (fi) | 1995-11-06 |
| DE69401583D1 (de) | 1997-03-06 |
| FI955304A (fi) | 1995-11-06 |
| EP0698024B1 (en) | 1997-01-22 |
| KR100304177B1 (ko) | 2001-11-22 |
| NO954402L (no) | 1996-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |