IL108461A - History of ellipticine, their preparation and pharmaceutical preparations containing them - Google Patents

History of ellipticine, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL108461A
IL108461A IL10846194A IL10846194A IL108461A IL 108461 A IL108461 A IL 108461A IL 10846194 A IL10846194 A IL 10846194A IL 10846194 A IL10846194 A IL 10846194A IL 108461 A IL108461 A IL 108461A
Authority
IL
Israel
Prior art keywords
group
protected
substituted
unprotected
lower alkoxy
Prior art date
Application number
IL10846194A
Other languages
English (en)
Hebrew (he)
Other versions
IL108461A0 (en
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of IL108461A0 publication Critical patent/IL108461A0/xx
Publication of IL108461A publication Critical patent/IL108461A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL10846194A 1993-01-29 1994-01-28 History of ellipticine, their preparation and pharmaceutical preparations containing them IL108461A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1344193 1993-01-29

Publications (2)

Publication Number Publication Date
IL108461A0 IL108461A0 (en) 1994-04-12
IL108461A true IL108461A (en) 1998-09-24

Family

ID=11833224

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10846194A IL108461A (en) 1993-01-29 1994-01-28 History of ellipticine, their preparation and pharmaceutical preparations containing them

Country Status (11)

Country Link
US (2) US5565569A (fr)
EP (1) EP0608876A1 (fr)
KR (1) KR940018385A (fr)
CN (1) CN1042731C (fr)
AU (1) AU666416B2 (fr)
CA (1) CA2114468A1 (fr)
FI (1) FI940403A (fr)
IL (1) IL108461A (fr)
MY (1) MY110683A (fr)
SG (1) SG42916A1 (fr)
TW (1) TW269688B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2696465B1 (fr) * 1992-10-02 1994-12-23 Adir Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2757859B1 (fr) * 1996-12-30 1999-01-29 Adir Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2757858B1 (fr) * 1996-12-30 1999-01-29 Adir Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6512102B1 (en) * 1998-12-31 2003-01-28 Chiron Corporation Compositions and methods of diagnosis and treatment using casein kinase I
EP2468277A1 (fr) * 2002-05-31 2012-06-27 Pharmagenesis, Inc. Dérivés de la triptolide pour la modulation de l'apoptose et l'immunosuppression
EP1877098B1 (fr) * 2005-05-05 2013-04-24 Chroma Therapeutics Limited Conjugués d'un ester d'aminoacide alpha et d'un médicament hydrolysables par la carboxylestérase
FR2925491B1 (fr) * 2007-12-19 2010-09-03 Oz Biosciences Sas Nouvelle classe de lipides cationiques pour le transport d'agents actifs dans les cellules
US20150119388A1 (en) * 2012-06-15 2015-04-30 The Children's Hospital Philadelphia Novel pro- and codrug derivatives for nanoparticle delivery of select anticancer agents formed using rapidly cleavable phenolic ester bridges

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933827A (en) * 1974-10-29 1976-01-20 Hoffmann-La Roche Inc. 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles
FR2308365A2 (fr) * 1975-04-25 1976-11-19 Anvar Derives de l'hydroxy-9 ellipticine et leur application therapeutique
US4310667A (en) * 1976-04-22 1982-01-12 Agence Nationale De Valorisation De La Recherche (Anvar) 2-N Quaternary ammonium salt derivatives of 9-hydroxy ellipticine
JPS6137799A (ja) * 1984-07-31 1986-02-22 Suntory Ltd エリプチシン誘導体およびその製造法
AU4245689A (en) * 1988-10-04 1990-04-12 Suntory Limited Ellipticine glycoside derivatives
JPH05310736A (ja) * 1992-05-06 1993-11-22 Tanabe Seiyaku Co Ltd エリプティシン誘導体、その製法およびその合成中間体
FR2696465B1 (fr) * 1992-10-02 1994-12-23 Adir Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5272146A (en) * 1992-10-02 1993-12-21 The United States Of America As Represented By The United States Department Of Health And Human Services 1,2-dihydroellipticines with activity against CNS specific cancer cell lines

Also Published As

Publication number Publication date
EP0608876A1 (fr) 1994-08-03
TW269688B (fr) 1996-02-01
MY110683A (en) 1999-01-30
FI940403A (fi) 1994-07-30
CN1042731C (zh) 1999-03-31
AU666416B2 (en) 1996-02-08
US5565569A (en) 1996-10-15
KR940018385A (ko) 1994-08-16
CN1099034A (zh) 1995-02-22
SG42916A1 (en) 1997-10-17
IL108461A0 (en) 1994-04-12
US5605904A (en) 1997-02-25
CA2114468A1 (fr) 1994-07-30
FI940403A0 (fi) 1994-01-27
AU5394794A (en) 1994-08-04

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void