IL107213A0 - Modified ciliary neurotrophic factors - Google Patents

Modified ciliary neurotrophic factors

Info

Publication number
IL107213A0
IL107213A0 IL107213A IL10721393A IL107213A0 IL 107213 A0 IL107213 A0 IL 107213A0 IL 107213 A IL107213 A IL 107213A IL 10721393 A IL10721393 A IL 10721393A IL 107213 A0 IL107213 A0 IL 107213A0
Authority
IL
Israel
Prior art keywords
neurotrophic factors
ciliary neurotrophic
modified ciliary
modified
screening
Prior art date
Application number
IL107213A
Other languages
English (en)
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of IL107213A0 publication Critical patent/IL107213A0/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
IL107213A 1992-10-09 1993-10-08 Modified ciliary neurotrophic factors IL107213A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/959,284 US5349056A (en) 1992-10-09 1992-10-09 Modified ciliary neurotrophic factors

Publications (1)

Publication Number Publication Date
IL107213A0 true IL107213A0 (en) 1994-01-25

Family

ID=25501875

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107213A IL107213A0 (en) 1992-10-09 1993-10-08 Modified ciliary neurotrophic factors

Country Status (14)

Country Link
US (5) US5349056A (ja)
EP (1) EP0666912B1 (ja)
JP (1) JP2702811B2 (ja)
AT (1) ATE151460T1 (ja)
AU (1) AU667996B2 (ja)
CA (1) CA2132954C (ja)
DE (1) DE69309702T2 (ja)
DK (1) DK0666912T3 (ja)
ES (1) ES2099981T3 (ja)
GR (1) GR3024039T3 (ja)
HK (1) HK1007767A1 (ja)
IL (1) IL107213A0 (ja)
WO (1) WO1994009134A2 (ja)
ZA (1) ZA937482B (ja)

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US6472178B1 (en) * 1998-02-27 2002-10-29 Regeneron Pharmaceuticals, Inc. Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
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US5939534A (en) * 1993-12-29 1999-08-17 Sumitomo Pharmaceuticals Company, Limited Factors mutated in the D1 cap region
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US5859311A (en) * 1995-11-27 1999-01-12 University Of Kentucky Research Foundation Transgenic mice which overexpress neurotrophin-3 (NT-3) and methods of use
IT1284867B1 (it) 1996-07-10 1998-05-22 Angeletti P Ist Richerche Bio Varianti del fattore neurotrofico ciliare umano (hcntf) con uno spettro di azione differente dalla molecola di tipo selvatico
BR9712824A (pt) 1996-09-13 1999-12-21 Advanced Medicine Research Ins Composição oftálmica de fator neurotrófico, agente de tratamento de desordem funcional do nervo ótico e método para tratamento de desordem funcional do nervo ótico
IT1288388B1 (it) * 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
US20040120891A1 (en) * 1998-12-21 2004-06-24 Craig Hill Compounds for intracellular delivery of therapeutic moieties to nerve cells
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AU2002253942A1 (en) * 2001-02-12 2002-08-28 Michael Amling Methods and compositions for control of bone formation via modulation of ciliary neurotrophic factor activity
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JP5583005B2 (ja) 2007-05-01 2014-09-03 バイオジェン・アイデック・エムエイ・インコーポレイテッド 血管新生を増大させるための組成物および方法
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US20100297081A1 (en) * 2007-12-18 2010-11-25 Huang Yanshan Pharmaceutical formulation containing recombinant human serum albumin-interferon alpha fusion protein
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US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US4997929A (en) * 1989-01-05 1991-03-05 Synergen, Inc. Purified ciliary neurotrophic factor
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JPH07500725A (ja) * 1991-07-23 1995-01-26 シンテックス−シナージェン　ニューロサイエンス　ジョイント　ベンチャー 組換え毛様体向神経因子およびｃ−末端切断毛様体向神経因子の精製ならびに末梢神経障害の処置方法
US5593857A (en) * 1991-08-23 1997-01-14 Scios Inc. Production of homogeneous truncated CNTF
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors

Also Published As

Publication number Publication date
EP0666912A1 (en) 1995-08-16
DE69309702D1 (de) 1997-05-15
ATE151460T1 (de) 1997-04-15
CA2132954A1 (en) 1994-04-28
AU667996B2 (en) 1996-04-18
CA2132954C (en) 2000-01-18
US20030220484A1 (en) 2003-11-27
US20030092129A1 (en) 2003-05-15
ZA937482B (en) 1994-04-26
WO1994009134A3 (en) 1994-05-26
US5846935A (en) 1998-12-08
AU5326094A (en) 1994-05-09
US5349056A (en) 1994-09-20
ES2099981T3 (es) 1997-06-01
JPH07506005A (ja) 1995-07-06
JP2702811B2 (ja) 1998-01-26
WO1994009134A2 (en) 1994-04-28
DK0666912T3 (da) 1997-09-29
HK1007767A1 (en) 1999-04-23
GR3024039T3 (en) 1997-10-31
US6440702B1 (en) 2002-08-27
DE69309702T2 (de) 1997-10-30
EP0666912B1 (en) 1997-04-09

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