IT1284867B1 - Varianti del fattore neurotrofico ciliare umano (hcntf) con uno spettro di azione differente dalla molecola di tipo selvatico - Google Patents
Varianti del fattore neurotrofico ciliare umano (hcntf) con uno spettro di azione differente dalla molecola di tipo selvaticoInfo
- Publication number
- IT1284867B1 IT1284867B1 IT96RM000492A ITRM960492A IT1284867B1 IT 1284867 B1 IT1284867 B1 IT 1284867B1 IT 96RM000492 A IT96RM000492 A IT 96RM000492A IT RM960492 A ITRM960492 A IT RM960492A IT 1284867 B1 IT1284867 B1 IT 1284867B1
- Authority
- IT
- Italy
- Prior art keywords
- hcntf
- human
- chiliary
- wild
- spectrum
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000492A IT1284867B1 (it) | 1996-07-10 | 1996-07-10 | Varianti del fattore neurotrofico ciliare umano (hcntf) con uno spettro di azione differente dalla molecola di tipo selvatico |
CA002260296A CA2260296C (en) | 1996-07-10 | 1997-07-10 | Variants of human ciliary neurotrophic factor (hcntf) with a range of action different from that of the wild-type molecule |
ES97932007T ES2265653T3 (es) | 1996-07-10 | 1997-07-10 | Variantes del factor neurotrofico ciliar humano (hcntf) con un intervalo de accion diferente del de la molecula de tipo silvestre. |
JP50501498A JP3329826B2 (ja) | 1996-07-10 | 1997-07-10 | 野性型分子とは異なる範囲の作用をもつヒト毛様体神経栄養因子(hCNTF)の変種 |
AU35576/97A AU719086B2 (en) | 1996-07-10 | 1997-07-10 | Variants of human ciliary neurotrophic factor (hCNTF) with a range of action different from that of the wild-type molecule |
IL12795997A IL127959A0 (en) | 1996-07-10 | 1997-07-10 | Variants of human ciliary neurotrophic factor (hcntf) with a range of action different from that of the wild-type molecule |
AT97932007T ATE331734T1 (de) | 1996-07-10 | 1997-07-10 | Neurotrophischer ziliarischer faktor mit geändertem aktivitätsbereich gegenüber dem wildtyp-molekül |
PCT/IT1997/000163 WO1998001149A2 (en) | 1996-07-10 | 1997-07-10 | VARIANTS OF HUMAN CILIARY NEUROTROPHIC FACTOR (hCNTF) WITH A RANGE OF ACTION DIFFERENT FROM THAT OF THE WILD-TYPE MOLECULE |
US09/214,718 US6756357B1 (en) | 1996-07-10 | 1997-07-10 | Variants of human ciliary neurotrophic factor (hCNTF) |
EP97932007A EP0936919B1 (en) | 1996-07-10 | 1997-07-10 | VARIANTS OF HUMAN CILIARY NEUROTROPHIC FACTOR (hCNTF) WITH A RANGE OF ACTION DIFFERENT FROM THAT OF THE WILD-TYPE MOLECULE |
DE69736241T DE69736241T2 (de) | 1996-07-10 | 1997-07-10 | Humaner neurotropher ciliarer Faktor mit geändertem Aktivitätsbereich gegenüber dem des Wildtyp-Moleküls |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000492A IT1284867B1 (it) | 1996-07-10 | 1996-07-10 | Varianti del fattore neurotrofico ciliare umano (hcntf) con uno spettro di azione differente dalla molecola di tipo selvatico |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM960492A0 ITRM960492A0 (it) | 1996-07-10 |
ITRM960492A1 ITRM960492A1 (it) | 1998-01-10 |
IT1284867B1 true IT1284867B1 (it) | 1998-05-22 |
Family
ID=11404333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT96RM000492A IT1284867B1 (it) | 1996-07-10 | 1996-07-10 | Varianti del fattore neurotrofico ciliare umano (hcntf) con uno spettro di azione differente dalla molecola di tipo selvatico |
Country Status (11)
Country | Link |
---|---|
US (1) | US6756357B1 (it) |
EP (1) | EP0936919B1 (it) |
JP (1) | JP3329826B2 (it) |
AT (1) | ATE331734T1 (it) |
AU (1) | AU719086B2 (it) |
CA (1) | CA2260296C (it) |
DE (1) | DE69736241T2 (it) |
ES (1) | ES2265653T3 (it) |
IL (1) | IL127959A0 (it) |
IT (1) | IT1284867B1 (it) |
WO (1) | WO1998001149A2 (it) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1288388B1 (it) * | 1996-11-19 | 1998-09-22 | Angeletti P Ist Richerche Bio | Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia |
IT1291114B1 (it) | 1997-03-20 | 1998-12-29 | Angeletti P Ist Richerche Bio | Varianti del fattore neurotrofico ciliare (cntf) con migliorata selettivita' al recettore, e metodo per la loro selezione |
AU2017370653B2 (en) * | 2016-12-06 | 2022-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Ciliary neurotrophic factor receptor ligand-binding agents and methods of using the same |
WO2018128745A1 (en) * | 2017-01-06 | 2018-07-12 | The Board Of Trustees Of The Leland Stanford Junior University | Ciliary neurotrophic factor receptor ligands and methods of using the same |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5349056A (en) * | 1992-10-09 | 1994-09-20 | Regeneron Pharmaceuticals | Modified ciliary neurotrophic factors |
AU1282895A (en) * | 1993-12-29 | 1995-07-17 | Sumitomo Pharmaceuticals Company, Limited | Novel human ciliary neurotrophic factor |
GB9413316D0 (en) | 1994-07-01 | 1994-08-24 | Cancer Res Campaign Tech | Novel proteins |
-
1996
- 1996-07-10 IT IT96RM000492A patent/IT1284867B1/it active IP Right Grant
-
1997
- 1997-07-10 AT AT97932007T patent/ATE331734T1/de not_active IP Right Cessation
- 1997-07-10 IL IL12795997A patent/IL127959A0/xx unknown
- 1997-07-10 AU AU35576/97A patent/AU719086B2/en not_active Ceased
- 1997-07-10 WO PCT/IT1997/000163 patent/WO1998001149A2/en active IP Right Grant
- 1997-07-10 ES ES97932007T patent/ES2265653T3/es not_active Expired - Lifetime
- 1997-07-10 DE DE69736241T patent/DE69736241T2/de not_active Expired - Lifetime
- 1997-07-10 EP EP97932007A patent/EP0936919B1/en not_active Expired - Lifetime
- 1997-07-10 US US09/214,718 patent/US6756357B1/en not_active Expired - Fee Related
- 1997-07-10 JP JP50501498A patent/JP3329826B2/ja not_active Expired - Fee Related
- 1997-07-10 CA CA002260296A patent/CA2260296C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69736241T2 (de) | 2007-05-31 |
CA2260296C (en) | 2006-05-16 |
DE69736241D1 (de) | 2006-08-10 |
JP2000507271A (ja) | 2000-06-13 |
ITRM960492A0 (it) | 1996-07-10 |
WO1998001149A2 (en) | 1998-01-15 |
CA2260296A1 (en) | 1998-01-15 |
JP3329826B2 (ja) | 2002-09-30 |
ES2265653T3 (es) | 2007-02-16 |
ITRM960492A1 (it) | 1998-01-10 |
IL127959A0 (en) | 1999-11-30 |
US6756357B1 (en) | 2004-06-29 |
ATE331734T1 (de) | 2006-07-15 |
AU3557697A (en) | 1998-02-02 |
WO1998001149A3 (en) | 1998-04-23 |
AU719086B2 (en) | 2000-05-04 |
EP0936919A2 (en) | 1999-08-25 |
EP0936919B1 (en) | 2006-06-28 |
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Legal Events
Date | Code | Title | Description |
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0001 | Granted |