IL106462A - Phenylimidazolidine derivatives their preparation and pharmaceutical compositions containing them - Google Patents

Phenylimidazolidine derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
IL106462A
IL106462A IL10646293A IL10646293A IL106462A IL 106462 A IL106462 A IL 106462A IL 10646293 A IL10646293 A IL 10646293A IL 10646293 A IL10646293 A IL 10646293A IL 106462 A IL106462 A IL 106462A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
phenylimidazolidine
derivatives
Prior art date
Application number
IL10646293A
Other languages
English (en)
Other versions
IL106462A0 (en
Original Assignee
Cassella Farbwerke Mainkur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag
Publication of IL106462A0 publication Critical patent/IL106462A0/xx
Publication of IL106462A publication Critical patent/IL106462A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/40—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL10646293A 1992-07-24 1993-07-23 Phenylimidazolidine derivatives their preparation and pharmaceutical compositions containing them IL106462A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4224414A DE4224414A1 (de) 1992-07-24 1992-07-24 Phenylimidazolidin-derivate, ihre Herstellung und ihre Verwendung

Publications (2)

Publication Number Publication Date
IL106462A0 IL106462A0 (en) 1993-11-15
IL106462A true IL106462A (en) 1997-02-18

Family

ID=6463969

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10646293A IL106462A (en) 1992-07-24 1993-07-23 Phenylimidazolidine derivatives their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US5424293A (sk)
EP (1) EP0580008B1 (sk)
JP (1) JP3775808B2 (sk)
KR (1) KR100418321B1 (sk)
AT (1) ATE168116T1 (sk)
AU (1) AU664630B2 (sk)
CA (1) CA2101179C (sk)
CZ (1) CZ289297B6 (sk)
DE (2) DE4224414A1 (sk)
DK (1) DK0580008T3 (sk)
ES (1) ES2119837T3 (sk)
HU (1) HU220767B1 (sk)
IL (1) IL106462A (sk)
SK (1) SK282517B6 (sk)
TW (1) TW306918B (sk)
ZA (1) ZA935341B (sk)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4308034A1 (de) * 1993-03-13 1994-09-15 Cassella Ag Neue Heterocyclen, ihre Herstellung und ihre Verwendung
DE4427979A1 (de) * 1993-11-15 1996-02-15 Cassella Ag Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung
US5849736A (en) * 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
US5563158A (en) * 1993-12-28 1996-10-08 The Dupont Merck Pharmaceutical Company Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists
ZA963391B (en) * 1995-05-24 1997-10-29 Du Pont Merck Pharma Isoxazoline fibrinogen receptor antagonists.
DE59706273D1 (de) * 1996-03-20 2002-03-21 Hoechst Ag Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
DE19622489A1 (de) 1996-06-05 1997-12-11 Hoechst Ag Salze des 3-(2-(4-(4-(Amino-imino-methyl)-phenyl)-4- methyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino)-3- phenyl-propionsäure-ethylesters
PL323130A1 (en) * 1996-11-15 1998-05-25 Hoechst Ag Application of heterocyclic compounds in production of a pharmaceutic agent, novel heterocyclic compounds and pharmaceutic agent as such
DE19647381A1 (de) * 1996-11-15 1998-05-20 Hoechst Ag Neue Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
DE19647380A1 (de) * 1996-11-15 1998-05-20 Hoechst Ag 5-Ring-Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
DE19741235A1 (de) 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US6163155A (en) * 1999-01-28 2000-12-19 Dresser Industries, Inc. Electromagnetic wave resistivity tool having a tilted antenna for determining the horizontal and vertical resistivities and relative dip angle in anisotropic earth formations
DE19922462A1 (de) 1999-05-17 2000-11-23 Aventis Pharma Gmbh Spiro-imidazolidinderivate, ihre Herstellung ihre Verwendung und sie enthaltende pharmazeutische Präparate
JP2003502442A (ja) 1999-06-17 2003-01-21 ソース・プリシジョン・メディシン・インク セリンエラスターゼの活性を阻害する方法及び化合物
DE10111877A1 (de) 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10137595A1 (de) * 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
JP5060555B2 (ja) * 2006-07-11 2012-10-31 ハリバートン エナジー サービシーズ，インコーポレーテッド モジュラー式ジオステアリング用ツールアセンブリ
MX2008014830A (es) * 2006-07-12 2009-03-05 Halliburton Energy Serv Inc Metodo y aparato para construir una antena inclinada.
WO2008115229A1 (en) * 2007-03-16 2008-09-25 Halliburton Energy Services, Inc. Robust inversion systems and methods for azimuthally sensitive resistivity logging tools
WO2010074678A2 (en) 2008-12-16 2010-07-01 Halliburton Energy Services, Inc. Azimuthal at-bit resistivity and geosteering methods and systems
BRPI1013305B1 (pt) 2010-01-22 2019-09-10 Halliburton Energy Services Inc sistema para medir uma resistividade de uma formação, método para determinar uma resistividade,e, broca de perfuração instrumentada
WO2014003702A1 (en) 2012-06-25 2014-01-03 Halliburton Energy Services, Inc. Tilted antenna logging systems and methods yielding robust measurement signals
WO2016172496A1 (en) 2015-04-23 2016-10-27 Constellation Pharmaceuticals, Inc. Lsd1 inhibitors and uses thereof
HRP20231369T1 (hr) 2016-10-26 2024-02-16 Constellation Pharmaceuticals, Inc. Inhibitori lsd1 i njihova medicinska upotreba

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4126277A1 (de) * 1991-08-08 1993-02-11 Cassella Ag Hydantoinderivate
DE4213634A1 (de) * 1992-04-24 1993-10-28 Cassella Ag 2,4-Dioxo-imidazolidin-Derivate

Also Published As

Publication number Publication date
CZ147593A3 (en) 1994-03-16
SK76993A3 (en) 1994-04-06
ZA935341B (en) 1994-02-14
AU4211993A (en) 1994-01-27
IL106462A0 (en) 1993-11-15
ES2119837T3 (es) 1998-10-16
US5424293A (en) 1995-06-13
JPH0725855A (ja) 1995-01-27
CA2101179A1 (en) 1994-01-25
SK282517B6 (sk) 2002-10-08
CA2101179C (en) 2003-10-28
TW306918B (sk) 1997-06-01
AU664630B2 (en) 1995-11-23
EP0580008B1 (de) 1998-07-08
DE59308732D1 (de) 1998-08-13
EP0580008A3 (de) 1995-03-15
HUT65141A (en) 1994-04-28
KR100418321B1 (ko) 2004-05-07
HU9302138D0 (en) 1993-10-28
KR940005583A (ko) 1994-03-21
DK0580008T3 (da) 1999-02-08
HU220767B1 (hu) 2002-05-28
ATE168116T1 (de) 1998-07-15
DE4224414A1 (de) 1994-01-27
CZ289297B6 (cs) 2001-12-12
JP3775808B2 (ja) 2006-05-17
EP0580008A2 (de) 1994-01-26

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees