IL104792A - Soluble salts of 4-amino-2-(4, 4-dimethylimidazolidin- 2-on-1-yl) pyrimidine- 5-carboxylic acid n-methyl-n- (3-trifluoromethylphenyl) amide, a process for the preparation thereof and the use thereof as pharmaceuticals and starting materials - Google Patents
Soluble salts of 4-amino-2-(4, 4-dimethylimidazolidin- 2-on-1-yl) pyrimidine- 5-carboxylic acid n-methyl-n- (3-trifluoromethylphenyl) amide, a process for the preparation thereof and the use thereof as pharmaceuticals and starting materialsInfo
- Publication number
- IL104792A IL104792A IL104792A IL10479293A IL104792A IL 104792 A IL104792 A IL 104792A IL 104792 A IL104792 A IL 104792A IL 10479293 A IL10479293 A IL 10479293A IL 104792 A IL104792 A IL 104792A
- Authority
- IL
- Israel
- Prior art keywords
- pyrimidine
- amide
- amino
- methyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4205483 | 1992-02-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL104792A0 IL104792A0 (en) | 1993-06-10 |
IL104792A true IL104792A (en) | 1997-09-30 |
Family
ID=6452363
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL104792A IL104792A (en) | 1992-02-22 | 1993-02-19 | Soluble salts of 4-amino-2-(4, 4-dimethylimidazolidin- 2-on-1-yl) pyrimidine- 5-carboxylic acid n-methyl-n- (3-trifluoromethylphenyl) amide, a process for the preparation thereof and the use thereof as pharmaceuticals and starting materials |
Country Status (16)
Country | Link |
---|---|
US (1) | US5795899A (hu) |
EP (1) | EP0557877B1 (hu) |
JP (1) | JP3258744B2 (hu) |
AT (1) | ATE158581T1 (hu) |
AU (2) | AU658265B2 (hu) |
CA (1) | CA2089956A1 (hu) |
DE (1) | DE59307402D1 (hu) |
DK (1) | DK0557877T3 (hu) |
ES (1) | ES2109382T3 (hu) |
FI (1) | FI105097B (hu) |
GR (1) | GR3025235T3 (hu) |
HU (1) | HU210621B (hu) |
IL (1) | IL104792A (hu) |
NO (1) | NO300892B1 (hu) |
NZ (2) | NZ245937A (hu) |
ZA (1) | ZA931183B (hu) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE147384T1 (de) * | 1992-02-22 | 1997-01-15 | Hoechst Ag | 4-amino-2-ureido-pyrimidin-5-carbonsäureamide, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
DE19625089A1 (de) * | 1996-06-24 | 1998-01-02 | Hoechst Ag | 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
DE19625088A1 (de) * | 1996-06-24 | 1998-01-02 | Hoechst Ag | 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
AU7683500A (en) * | 1999-10-12 | 2001-04-23 | Takeda Chemical Industries Ltd. | Pyrimidine-5-carboxamide compounds, process for producing the same and use thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2853220A1 (de) * | 1978-12-09 | 1980-07-03 | Hoechst Ag | Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung |
DE3522940A1 (de) * | 1985-06-27 | 1987-01-08 | Hoechst Ag | 4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln |
ATE147384T1 (de) * | 1992-02-22 | 1997-01-15 | Hoechst Ag | 4-amino-2-ureido-pyrimidin-5-carbonsäureamide, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
-
1993
- 1993-02-17 DK DK93102451.7T patent/DK0557877T3/da active
- 1993-02-17 DE DE59307402T patent/DE59307402D1/de not_active Expired - Fee Related
- 1993-02-17 ES ES93102451T patent/ES2109382T3/es not_active Expired - Lifetime
- 1993-02-17 EP EP93102451A patent/EP0557877B1/de not_active Expired - Lifetime
- 1993-02-17 AT AT93102451T patent/ATE158581T1/de not_active IP Right Cessation
- 1993-02-18 FI FI930718A patent/FI105097B/fi active
- 1993-02-19 ZA ZA931183A patent/ZA931183B/xx unknown
- 1993-02-19 HU HU9300459A patent/HU210621B/hu not_active IP Right Cessation
- 1993-02-19 NZ NZ245937A patent/NZ245937A/en unknown
- 1993-02-19 JP JP03002193A patent/JP3258744B2/ja not_active Expired - Fee Related
- 1993-02-19 CA CA002089956A patent/CA2089956A1/en not_active Abandoned
- 1993-02-19 AU AU33760/93A patent/AU658265B2/en not_active Ceased
- 1993-02-19 IL IL104792A patent/IL104792A/xx not_active IP Right Cessation
- 1993-02-19 NZ NZ264767A patent/NZ264767A/en unknown
- 1993-02-19 NO NO930595A patent/NO300892B1/no not_active IP Right Cessation
-
1995
- 1995-01-24 AU AU11365/95A patent/AU669463B2/en not_active Ceased
- 1995-02-23 US US08/394,521 patent/US5795899A/en not_active Expired - Fee Related
-
1997
- 1997-10-31 GR GR970402871T patent/GR3025235T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2109382T3 (es) | 1998-01-16 |
JPH06184137A (ja) | 1994-07-05 |
NZ245937A (en) | 1994-12-22 |
NO930595L (no) | 1993-08-23 |
EP0557877B1 (de) | 1997-09-24 |
EP0557877A1 (de) | 1993-09-01 |
NO930595D0 (no) | 1993-02-19 |
NZ264767A (en) | 1995-10-26 |
AU669463B2 (en) | 1996-06-06 |
FI105097B (fi) | 2000-06-15 |
HUT63410A (en) | 1993-08-30 |
CA2089956A1 (en) | 1993-08-23 |
HU210621B (en) | 1995-06-28 |
ATE158581T1 (de) | 1997-10-15 |
FI930718A (fi) | 1993-08-23 |
AU3376093A (en) | 1993-08-26 |
JP3258744B2 (ja) | 2002-02-18 |
FI930718A0 (fi) | 1993-02-18 |
DK0557877T3 (da) | 1998-04-27 |
US5795899A (en) | 1998-08-18 |
AU658265B2 (en) | 1995-04-06 |
DE59307402D1 (de) | 1997-10-30 |
NO300892B1 (no) | 1997-08-11 |
AU1136595A (en) | 1995-04-13 |
GR3025235T3 (en) | 1998-02-27 |
HU9300459D0 (en) | 1993-05-28 |
ZA931183B (en) | 1993-09-16 |
IL104792A0 (en) | 1993-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
RH | Patent void | ||
RH1 | Patent not in force |