IL104574A - N-[[3,4-dichlorophenyl)amino] carbonyl]-2,3-dihydro benzofuran-5-sulfonamide its preparation and antitumor compositions containing it and uses thereof - Google Patents

N-[[3,4-dichlorophenyl)amino] carbonyl]-2,3-dihydro benzofuran-5-sulfonamide its preparation and antitumor compositions containing it and uses thereof

Info

Publication number
IL104574A
IL104574A IL10457493A IL10457493A IL104574A IL 104574 A IL104574 A IL 104574A IL 10457493 A IL10457493 A IL 10457493A IL 10457493 A IL10457493 A IL 10457493A IL 104574 A IL104574 A IL 104574A
Authority
IL
Israel
Prior art keywords
dichlorophenyl
carbonyl
amino
sulfonamide
preparation
Prior art date
Application number
IL10457493A
Other languages
English (en)
Other versions
IL104574A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL104574A0 publication Critical patent/IL104574A0/xx
Publication of IL104574A publication Critical patent/IL104574A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Undergarments, Swaddling Clothes, Handkerchiefs Or Underwear Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL10457493A 1992-02-05 1993-02-01 N-[[3,4-dichlorophenyl)amino] carbonyl]-2,3-dihydro benzofuran-5-sulfonamide its preparation and antitumor compositions containing it and uses thereof IL104574A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/831,604 US5254582A (en) 1992-02-05 1992-02-05 Antitumor compositions and methods

Publications (2)

Publication Number Publication Date
IL104574A0 IL104574A0 (en) 1993-06-10
IL104574A true IL104574A (en) 1997-02-18

Family

ID=25259448

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10457493A IL104574A (en) 1992-02-05 1993-02-01 N-[[3,4-dichlorophenyl)amino] carbonyl]-2,3-dihydro benzofuran-5-sulfonamide its preparation and antitumor compositions containing it and uses thereof

Country Status (25)

Country Link
US (1) US5254582A (fi)
EP (1) EP0555036B1 (fi)
JP (1) JP3210117B2 (fi)
KR (1) KR100246148B1 (fi)
CN (1) CN1044239C (fi)
AT (1) ATE170853T1 (fi)
AU (1) AU658043B2 (fi)
BR (1) BR9300469A (fi)
CA (1) CA2088719A1 (fi)
CY (1) CY2101B1 (fi)
CZ (1) CZ282753B6 (fi)
DE (1) DE69320844T2 (fi)
DK (1) DK0555036T3 (fi)
ES (1) ES2121940T3 (fi)
FI (1) FI930453A (fi)
HU (2) HU213231B (fi)
IL (1) IL104574A (fi)
MX (1) MX9300558A (fi)
MY (1) MY109640A (fi)
NO (1) NO302472B1 (fi)
NZ (1) NZ245818A (fi)
RU (1) RU2072996C1 (fi)
SG (1) SG79181A1 (fi)
YU (1) YU48915B (fi)
ZA (1) ZA93689B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
US5529999A (en) * 1994-03-04 1996-06-25 Eli Lilly And Company Antitumor compositions and methods of treatment
EP1021437B1 (en) * 1996-08-22 2001-11-14 Dong Wha Pharmaceutical Industrial Co. Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
EP0929540A4 (en) * 1996-10-04 2001-12-12 Lilly Co Eli ANTI-TUMOR COMPOSITIONS AND THERAPEUTIC METHODS
US6281240B1 (en) * 1997-04-10 2001-08-28 Eli Lilly And Company Diarylsulfonylureas for use in treating secretory diarrhea
US5932407A (en) * 1997-04-30 1999-08-03 Eastman Kodak Company Color photographic element containing oxidized developer-scavenging naphtholic coupler forming wash-out dye
CL2004001834A1 (es) 2003-07-23 2005-06-03 Bayer Pharmaceuticals Corp Compuesto 4-{4-[3-(4-cloro-3-trifluorometilfenil)-ureido]-3-fluorofenoxi}-piridin-2-metilamida, inhibidor de la raf, vegfr, p38 y pdgfr quinasas, sus sales; composiicon farmaceutica; combinacion farmaceutica; y su uso para tratar trastornos hiperprol
WO2006030941A1 (ja) * 2004-09-13 2006-03-23 Eisai R & D Management Co., Ltd. スルホンアミド含有化合物の血管新生阻害物質との併用
JP5134247B2 (ja) * 2004-09-13 2013-01-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド含有化合物の血管新生阻害物質との併用
US8772269B2 (en) 2004-09-13 2014-07-08 Eisai R&D Management Co., Ltd. Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
US20100291592A1 (en) 2006-04-20 2010-11-18 Taro Semba Novel marker for sensitivity against sulfonamide compound
CN104941647B (zh) * 2015-06-18 2017-07-04 四川之江高新材料股份有限公司 合成n‑甲基吗啉的方法及所用的负载型催化剂

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3083207A (en) * 1963-03-26 Indolinesulfonylureas
US1208561A (en) * 1914-09-14 1916-12-12 Stephen E Huff Sound-box attachment for phonographs.
US3097242A (en) * 1960-06-29 1963-07-09 Olin Mathieson Hydrindene sulfonylureas
US3102121A (en) * 1961-06-29 1963-08-27 Olin Mathieson Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas
NL295122A (fi) * 1962-04-11
US3849110A (en) * 1963-01-07 1974-11-19 Lilly Co Eli Herbicidal method employing aryl-sulfonylureas or salts thereof
US3736122A (en) * 1969-04-10 1973-05-29 C Tung Method of controlling plant growth
AU1862083A (en) * 1982-09-02 1984-03-08 Duphar International Research B.V. Tumor growth inhibitors
CA1208561A (en) * 1984-01-19 1986-07-29 Marius S. Brouwer Pharmaceutical compositions containing benzoylurea compounds
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
JPS6163671A (ja) * 1984-09-05 1986-04-01 Shionogi & Co Ltd ２，３−ジヒドロベンゾフラン−５−スルホンアミド誘導体および降圧利尿剤
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
GR862353B (en) * 1985-09-23 1987-01-19 Lilly Co Eli Anti-tumor method and compounds
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds
ZA915371B (en) * 1990-07-17 1993-03-31 Lilly Co Eli Antitumor compositions and methods of treatment
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment

Also Published As

Publication number Publication date
MY109640A (en) 1997-03-31
ZA93689B (en) 1994-08-01
NO302472B1 (no) 1998-03-09
CN1044239C (zh) 1999-07-21
BR9300469A (pt) 1993-08-10
RU2072996C1 (ru) 1997-02-10
HU213231B (en) 1997-03-28
CY2101B1 (en) 2002-04-05
CA2088719A1 (en) 1993-08-06
SG79181A1 (en) 2001-03-20
AU658043B2 (en) 1995-03-30
DE69320844D1 (de) 1998-10-15
HU211561A9 (en) 1995-12-28
EP0555036A2 (en) 1993-08-11
ES2121940T3 (es) 1998-12-16
EP0555036A3 (en) 1993-11-24
CZ12093A3 (en) 1993-12-15
DE69320844T2 (de) 1999-03-04
KR100246148B1 (ko) 2000-04-01
ATE170853T1 (de) 1998-09-15
DK0555036T3 (da) 1999-06-07
JPH05306277A (ja) 1993-11-19
IL104574A0 (en) 1993-06-10
AU3218393A (en) 1993-08-12
YU5893A (sh) 1996-07-24
US5254582A (en) 1993-10-19
NZ245818A (en) 1995-03-28
YU48915B (sh) 2002-11-15
EP0555036B1 (en) 1998-09-09
HUT63842A (en) 1993-10-28
CN1075961A (zh) 1993-09-08
MX9300558A (es) 1993-08-01
NO930380L (no) 1993-08-06
JP3210117B2 (ja) 2001-09-17
FI930453A (fi) 1993-08-06
FI930453A0 (fi) 1993-02-02
HU9300288D0 (en) 1993-04-28
KR930017885A (ko) 1993-09-20
CZ282753B6 (cs) 1997-09-17
NO930380D0 (no) 1993-02-03

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH1 Patent not in force