IL103817A0 - Method and intermediates for the preparation of prolineboronic acid esters - Google Patents

Method and intermediates for the preparation of prolineboronic acid esters

Info

Publication number
IL103817A0
IL103817A0 IL103817A IL10381792A IL103817A0 IL 103817 A0 IL103817 A0 IL 103817A0 IL 103817 A IL103817 A IL 103817A IL 10381792 A IL10381792 A IL 10381792A IL 103817 A0 IL103817 A0 IL 103817A0
Authority
IL
Israel
Prior art keywords
intermediates
preparation
acid esters
prolineboronic acid
prolineboronic
Prior art date
Application number
IL103817A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL103817A0 publication Critical patent/IL103817A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL103817A 1991-11-22 1992-11-20 Method and intermediates for the preparation of prolineboronic acid esters IL103817A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79614891A 1991-11-22 1991-11-22
US93619892A 1992-08-26 1992-08-26

Publications (1)

Publication Number Publication Date
IL103817A0 true IL103817A0 (en) 1993-04-04

Family

ID=27121696

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103817A IL103817A0 (en) 1991-11-22 1992-11-20 Method and intermediates for the preparation of prolineboronic acid esters

Country Status (17)

Country Link
EP (1) EP0641347A1 (fi)
JP (1) JPH07501078A (fi)
CN (1) CN1073946A (fi)
AU (1) AU661362B2 (fi)
CA (1) CA2123128A1 (fi)
CZ (1) CZ124494A3 (fi)
FI (1) FI942345A0 (fi)
HU (1) HUT67937A (fi)
IL (1) IL103817A0 (fi)
MX (1) MX9206628A (fi)
NO (1) NO941905L (fi)
NZ (1) NZ245207A (fi)
PT (1) PT101079A (fi)
SI (1) SI9200332A (fi)
SK (1) SK59294A3 (fi)
TW (1) TW232697B (fi)
WO (1) WO1993010127A1 (fi)

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US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
AU2001233622A1 (en) * 2000-02-25 2001-09-03 Novo-Nordisk A/S Inhibition of beta cell degeneration
WO2003063903A2 (en) * 2002-02-01 2003-08-07 Probiodrug Ag Modulation of t lymphocytes using dp iv inhibitors
US7576121B2 (en) 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
ES2524916T3 (es) 2003-11-12 2014-12-15 Sino-Med International Alliance, Inc. Compuestos heterocíclicos de ácido borónico
US7767828B2 (en) 2003-11-12 2010-08-03 Phenomix Corporation Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7317109B2 (en) 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
MXPA06005518A (es) 2003-11-17 2006-08-17 Novartis Ag Uso de inhibidores de la dipeptidil peptidasa iv.
ES2684325T5 (es) 2004-01-20 2024-06-10 Novartis Ag Formulación y proceso de compresión directa
US7446211B2 (en) 2004-04-27 2008-11-04 Wyeth Coupling process for generating reactive boron-containing derivatives of N-substituted pyrrole-2-carbonitriles to produce biaryls
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EP1943257A2 (en) 2005-05-19 2008-07-16 Genentech, Inc. Fibroblast activation protein inhibitor compounds and methods
US7825139B2 (en) 2005-05-25 2010-11-02 Forest Laboratories Holdings Limited (BM) Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
CN1331835C (zh) * 2005-10-18 2007-08-15 武汉大学 光活性β－羟基酮的制备方法
KR20150003157A (ko) 2005-12-19 2015-01-08 트러스티즈 오브 터프츠 칼리지 소프트 단백질분해효소 억제자 및 이의 프로-소프트 폼
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
PL1971862T3 (pl) 2006-04-11 2011-04-29 Arena Pharm Inc Sposoby stosowania receptora GPR119 w celu identyfikacji związków przydatnych w zwiększeniu masy kostnej osobnika
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GEP201706703B (en) * 2008-06-17 2017-07-25 Millennium Pharmaceuticals Inc (A Delaware Corporation) Boronate ester compounds and pharmaceutical compositions thereof
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US4935493A (en) * 1987-10-06 1990-06-19 E. I. Du Pont De Nemours And Company Protease inhibitors
JPH05508624A (ja) * 1990-04-14 1993-12-02 ニュー　イングランド　メデカル　センター　ホスピタルズ　インク ジペプチジル―アミノベプチダーゼ・４型の阻害剤
GB9017694D0 (en) * 1990-08-13 1990-09-26 Sandoz Ltd Improvements in or relating to organic chemistry

Also Published As

Publication number Publication date
NO941905D0 (no) 1994-05-20
EP0641347A1 (en) 1995-03-08
JPH07501078A (ja) 1995-02-02
SI9200332A (en) 1993-06-30
NZ245207A (en) 1994-07-26
CA2123128A1 (en) 1993-05-27
HUT67937A (en) 1995-05-29
FI942345A (fi) 1994-05-20
FI942345A0 (fi) 1994-05-20
PT101079A (pt) 1994-02-28
CZ124494A3 (en) 1995-07-12
AU3136893A (en) 1993-06-15
SK59294A3 (en) 1995-02-08
TW232697B (fi) 1994-10-21
AU661362B2 (en) 1995-07-20
CN1073946A (zh) 1993-07-07
NO941905L (no) 1994-07-14
MX9206628A (es) 1993-05-01
WO1993010127A1 (en) 1993-05-27
HU9401350D0 (en) 1994-08-29

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