HUT67937A - Method for making prolineboronate esters - Google Patents

Method for making prolineboronate esters

Info

Publication number
HUT67937A
HUT67937A HU9401350A HU9401350A HUT67937A HU T67937 A HUT67937 A HU T67937A HU 9401350 A HU9401350 A HU 9401350A HU 9401350 A HU9401350 A HU 9401350A HU T67937 A HUT67937 A HU T67937A
Authority
HU
Hungary
Prior art keywords
prolineboronate
esters
making
prolineboronate esters
making prolineboronate
Prior art date
Application number
HU9401350A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9401350D0 (en
Inventor
Julian Adams
Roger Snow
Terence A Kelly
Simon Coutts
Clark Perry
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of HU9401350D0 publication Critical patent/HU9401350D0/hu
Publication of HUT67937A publication Critical patent/HUT67937A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9401350A 1991-11-22 1992-11-19 Method for making prolineboronate esters HUT67937A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79614891A 1991-11-22 1991-11-22
US93619892A 1992-08-26 1992-08-26

Publications (2)

Publication Number Publication Date
HU9401350D0 HU9401350D0 (en) 1994-08-29
HUT67937A true HUT67937A (en) 1995-05-29

Family

ID=27121696

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9401350A HUT67937A (en) 1991-11-22 1992-11-19 Method for making prolineboronate esters

Country Status (17)

Country Link
EP (1) EP0641347A1 (fi)
JP (1) JPH07501078A (fi)
CN (1) CN1073946A (fi)
AU (1) AU661362B2 (fi)
CA (1) CA2123128A1 (fi)
CZ (1) CZ124494A3 (fi)
FI (1) FI942345A0 (fi)
HU (1) HUT67937A (fi)
IL (1) IL103817A0 (fi)
MX (1) MX9206628A (fi)
NO (1) NO941905L (fi)
NZ (1) NZ245207A (fi)
PT (1) PT101079A (fi)
SI (1) SI9200332A (fi)
SK (1) SK59294A3 (fi)
TW (1) TW232697B (fi)
WO (1) WO1993010127A1 (fi)

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DE69905038T2 (de) 1998-06-05 2003-06-05 Point Therapeutics Inc Cyclische boroprolinverbindungen
US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
AU2001233622A1 (en) * 2000-02-25 2001-09-03 Novo-Nordisk A/S Inhibition of beta cell degeneration
WO2003063903A2 (en) * 2002-02-01 2003-08-07 Probiodrug Ag Modulation of t lymphocytes using dp iv inhibitors
US7576121B2 (en) 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
ES2524916T3 (es) 2003-11-12 2014-12-15 Sino-Med International Alliance, Inc. Compuestos heterocíclicos de ácido borónico
US7767828B2 (en) 2003-11-12 2010-08-03 Phenomix Corporation Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7317109B2 (en) 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
MXPA06005518A (es) 2003-11-17 2006-08-17 Novartis Ag Uso de inhibidores de la dipeptidil peptidasa iv.
ES2684325T5 (es) 2004-01-20 2024-06-10 Novartis Ag Formulación y proceso de compresión directa
US7446211B2 (en) 2004-04-27 2008-11-04 Wyeth Coupling process for generating reactive boron-containing derivatives of N-substituted pyrrole-2-carbonitriles to produce biaryls
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EP1943257A2 (en) 2005-05-19 2008-07-16 Genentech, Inc. Fibroblast activation protein inhibitor compounds and methods
US7825139B2 (en) 2005-05-25 2010-11-02 Forest Laboratories Holdings Limited (BM) Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
CN1331835C (zh) * 2005-10-18 2007-08-15 武汉大学 光活性β－羟基酮的制备方法
KR20150003157A (ko) 2005-12-19 2015-01-08 트러스티즈 오브 터프츠 칼리지 소프트 단백질분해효소 억제자 및 이의 프로-소프트 폼
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
PL1971862T3 (pl) 2006-04-11 2011-04-29 Arena Pharm Inc Sposoby stosowania receptora GPR119 w celu identyfikacji związków przydatnych w zwiększeniu masy kostnej osobnika
EP2146210A1 (en) 2008-04-07 2010-01-20 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY
GEP201706703B (en) * 2008-06-17 2017-07-25 Millennium Pharmaceuticals Inc (A Delaware Corporation) Boronate ester compounds and pharmaceutical compositions thereof
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WO2018162722A1 (en) 2017-03-09 2018-09-13 Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Dpp-4 inhibitors for use in treating bone fractures
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CN108047257B (zh) * 2017-12-17 2020-03-13 沧州普瑞东方科技有限公司 一种手性n-boc-吡咯烷-2-硼酸的制备工艺
CN110452258B (zh) * 2019-09-03 2021-01-01 上海馨远医药科技有限公司 一种二肽缬氨酸硼脯氨酸盐的制备方法

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* Cited by examiner, † Cited by third party
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US4935493A (en) * 1987-10-06 1990-06-19 E. I. Du Pont De Nemours And Company Protease inhibitors
JPH05508624A (ja) * 1990-04-14 1993-12-02 ニュー　イングランド　メデカル　センター　ホスピタルズ　インク ジペプチジル―アミノベプチダーゼ・４型の阻害剤
GB9017694D0 (en) * 1990-08-13 1990-09-26 Sandoz Ltd Improvements in or relating to organic chemistry

Also Published As

Publication number Publication date
NO941905D0 (no) 1994-05-20
EP0641347A1 (en) 1995-03-08
JPH07501078A (ja) 1995-02-02
IL103817A0 (en) 1993-04-04
SI9200332A (en) 1993-06-30
NZ245207A (en) 1994-07-26
CA2123128A1 (en) 1993-05-27
FI942345A (fi) 1994-05-20
FI942345A0 (fi) 1994-05-20
PT101079A (pt) 1994-02-28
CZ124494A3 (en) 1995-07-12
AU3136893A (en) 1993-06-15
SK59294A3 (en) 1995-02-08
TW232697B (fi) 1994-10-21
AU661362B2 (en) 1995-07-20
CN1073946A (zh) 1993-07-07
NO941905L (no) 1994-07-14
MX9206628A (es) 1993-05-01
WO1993010127A1 (en) 1993-05-27
HU9401350D0 (en) 1994-08-29

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee