IL103711A - Transdermal drug delivery device - Google Patents

Transdermal drug delivery device

Info

Publication number
IL103711A
IL103711A IL10371192A IL10371192A IL103711A IL 103711 A IL103711 A IL 103711A IL 10371192 A IL10371192 A IL 10371192A IL 10371192 A IL10371192 A IL 10371192A IL 103711 A IL103711 A IL 103711A
Authority
IL
Israel
Prior art keywords
drug
electrode
pct
skin
reservoir
Prior art date
Application number
IL10371192A
Other languages
English (en)
Other versions
IL103711A0 (en
Original Assignee
Elan Corp Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp Plc filed Critical Elan Corp Plc
Publication of IL103711A0 publication Critical patent/IL103711A0/xx
Publication of IL103711A publication Critical patent/IL103711A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10371192A 1991-11-13 1992-11-11 Transdermal drug delivery device IL103711A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE394191 1991-11-13

Publications (2)

Publication Number Publication Date
IL103711A0 IL103711A0 (en) 1993-04-04
IL103711A true IL103711A (en) 1997-02-18

Family

ID=11039234

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10371192A IL103711A (en) 1991-11-13 1992-11-11 Transdermal drug delivery device

Country Status (11)

Country Link
US (1) US5533995A (xx)
EP (1) EP0612258B1 (xx)
JP (1) JP3456994B2 (xx)
AT (1) ATE155045T1 (xx)
AU (1) AU664214B2 (xx)
CA (1) CA2123428A1 (xx)
DE (1) DE69220808T2 (xx)
IL (1) IL103711A (xx)
NZ (1) NZ245091A (xx)
WO (1) WO1993009842A1 (xx)
ZA (1) ZA928689B (xx)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2112552T3 (es) * 1992-06-02 1998-04-01 Alza Corp Dispositivo para la administracion de un medicamento por electrotransporte.
SE501638C2 (sv) * 1993-08-17 1995-04-03 Perimed Ab Anordning för jontoforetisk administrering, innefattande minst en laser-dopplerprobe, samt användning av anordningen
KR0134151B1 (ko) * 1994-05-23 1998-04-14 이형도 인슐린 패치
FR2726769B1 (fr) * 1994-11-16 1997-01-31 Lhd Lab Hygiene Dietetique Dispositif ionophoretique d'administration transdermique de medicaments et ensemble jetable formant partie d'un tel dispositif
US5866629A (en) * 1995-12-05 1999-02-02 The University Of Toronto Innovations Foundation Dental and medical primer formulations containing tissue infiltrating agents
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5971722A (en) * 1997-09-05 1999-10-26 Baxter International Inc Electrochemical syringe pump having a sealed storage reservoir for a charge transfer medium
US6757560B1 (en) * 1999-04-09 2004-06-29 Novosis Pharma Ag Transdermal delivery system (TDS) with electrode network
AU4188100A (en) * 1999-04-08 2000-11-14 Gregory M. Glenn Dry formulation for transcutaneous immunization
WO2001035928A1 (en) * 1999-11-17 2001-05-25 Microchips, Inc. Microfabricated devices for the delivery of molecules into a carrier fluid
ATE323470T1 (de) * 1999-12-10 2006-05-15 Massachusetts Inst Technology Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren
DE60144142D1 (de) * 2000-03-02 2011-04-14 Microchips Inc Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien
EP1339312B1 (en) * 2000-10-10 2006-01-04 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
ATE359762T1 (de) * 2001-01-09 2007-05-15 Microchips Inc Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation
ATE398461T1 (de) 2001-02-13 2008-07-15 Us Gov Sec Army Impstoffe zur transkutanen immunisierung gegen reisediarrhö
JP4320177B2 (ja) * 2001-04-04 2009-08-26 アルザ・コーポレーシヨン 抗微生物適合性レザバー組成物を含む経皮性電気輸送デリバリー装置
AU2002326304A1 (en) * 2001-05-31 2002-12-16 Massachusetts Institute Of Technology Microchip devices with improved reservoir opening
US6827250B2 (en) * 2001-06-28 2004-12-07 Microchips, Inc. Methods for hermetically sealing microchip reservoir devices
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6975902B2 (en) * 2002-06-28 2005-12-13 Alza Corporation Reservoir and a series of related reservoirs for use in an electrotransport drug delivery device and devices comprised thereof
CN100594892C (zh) * 2002-08-16 2010-03-24 微芯片公司 使用电热消融的受控释放的装置和方法
WO2004026281A2 (en) * 2002-09-23 2004-04-01 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
KR20050088079A (ko) 2002-11-15 2005-09-01 이데닉스 (케이만) 리미티드 2'-분지형 뉴클레오시드 및 플라비비리다에 돌연변이
ATE366601T1 (de) * 2003-03-12 2007-08-15 Novosis Ag Transdermales wirkstoffverabreichungssystem mit elektrodenraster
WO2005016558A2 (en) * 2003-08-04 2005-02-24 Microchips, Inc. Methods for accelerated release of material from a reservoir device
WO2005041767A2 (en) * 2003-11-03 2005-05-12 Microchips, Inc. Medical device for sensing glucose
IL159273A0 (en) * 2003-12-09 2004-06-01 Transpharma Medical Ltd Transdermal delivery system for sustained release of polypeptides
AU2005224182B2 (en) * 2004-03-19 2008-04-17 Mcneil Ab Means for transdermal administration of nicotine
JP2008501037A (ja) * 2004-06-01 2008-01-17 マイクロチップス・インコーポレーテッド 医療移植片への/医療移植片からの薬物または分析物の輸送の測定および輸送の増強のためのデバイスおよび方法
US20080280973A1 (en) * 2004-06-28 2008-11-13 Wender Paul A Laulimalide Analogues as Therapeutic Agents
US7537590B2 (en) * 2004-07-30 2009-05-26 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
AU2005279729B2 (en) * 2004-09-01 2010-12-02 Microchips, Inc. Multi-cap reservoir devices for controlled release or exposure of reservoir contents
US7413846B2 (en) * 2004-11-15 2008-08-19 Microchips, Inc. Fabrication methods and structures for micro-reservoir devices
US7488316B2 (en) * 2005-01-25 2009-02-10 Microchips, Inc. Control of drug release by transient modification of local microenvironments
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
US20080009788A1 (en) * 2005-02-11 2008-01-10 Hunter Ian W Surface injection device
US20060258986A1 (en) * 2005-02-11 2006-11-16 Hunter Ian W Controlled needle-free transport
US7833189B2 (en) 2005-02-11 2010-11-16 Massachusetts Institute Of Technology Controlled needle-free transport
WO2007058966A1 (en) * 2005-11-11 2007-05-24 Massachusetts Institute Of Technology Controlled needle-free eye injector
US20070275035A1 (en) * 2006-05-24 2007-11-29 Microchips, Inc. Minimally Invasive Medical Implant Devices for Controlled Drug Delivery
CA2666755C (en) * 2006-09-01 2014-03-25 Massachusetts Institute Of Technology Needle-free injector device with autoloading capability
WO2009000262A1 (de) * 2007-06-25 2008-12-31 Acino Ag Elektrophoretisches transdermales applikationssystem
US8398583B2 (en) * 2008-07-09 2013-03-19 Massachusetts Institute Of Technology Method and apparatus for extraction of a sample from a sample source
KR101674904B1 (ko) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 중재형 약물전달 시스템과 그 방법
US8758271B2 (en) 2009-09-01 2014-06-24 Massachusetts Institute Of Technology Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties
US20110143310A1 (en) 2009-12-15 2011-06-16 Hunter Ian W Lorentz-Force Actuated Cleaning Device
DE102010024558B4 (de) 2010-06-22 2016-04-21 Amw Gmbh Transdermales therapeutisches System mit Elektroden
US9089574B2 (en) 2011-11-30 2015-07-28 Emory University Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections
EP2874693A1 (en) * 2012-07-20 2015-05-27 Grünenthal GmbH Electric-field assisted administration of tapentadol
US10472334B2 (en) 2014-03-14 2019-11-12 The University Of North Carolina At Chapel Hill Small molecules for inhibiting male fertility
KR101887088B1 (ko) * 2017-02-28 2018-08-09 (주)강앤박메디컬 무 바늘 용액 주입 장치 및 이를 이용한 무 바늘 용액 주입 방법
TWI670089B (zh) 2017-03-24 2019-09-01 美商伊英克加利福尼亞有限責任公司 用於調節活性物投送速率之包含帶電或磁性粒子的微胞遞送系統
CN110461314A (zh) 2017-03-24 2019-11-15 伊英克加利福尼亚有限责任公司 用于递送活性分子的微单元系统
JP6972334B2 (ja) 2017-11-14 2021-11-24 イー インク カリフォルニア, エルエルシー 多孔性伝導電極層を含む電気泳動活性分子送達システム
JP7438346B2 (ja) 2019-11-27 2024-02-26 イー インク コーポレイション 電気浸食シール層を有するマイクロセルを備えている有益剤送達システム
JP2023545106A (ja) 2020-10-29 2023-10-26 イー インク カリフォルニア, エルエルシー 親水性活性分子を送達するためのマイクロセルシステム
CN116322881A (zh) 2020-10-29 2023-06-23 伊英克加利福尼亚有限责任公司 用于递送有益剂的微单元系统

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923426A (en) * 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US4943435A (en) * 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
CA2001446C (en) * 1988-10-28 2000-08-01 Joseph Bradley Phipps Iontophoresis electrode
US5041107A (en) * 1989-10-06 1991-08-20 Cardiac Pacemakers, Inc. Electrically controllable, non-occluding, body implantable drug delivery system
IT1244030B (it) * 1989-12-21 1994-06-28 Elan Corp Plc Dispostitivo in due parti per la somministrazione controllata di un ingrediente
US5156591A (en) * 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
IL97099A0 (en) * 1991-01-30 1992-03-29 Scient Innovations Ltd Infusion pump with safety means controlling the electrolytic cell
US5356632A (en) * 1991-09-12 1994-10-18 S.I. Scientific Innovations Ltd. Transdermal drug delivery device

Also Published As

Publication number Publication date
DE69220808D1 (de) 1997-08-14
JP3456994B2 (ja) 2003-10-14
EP0612258A1 (en) 1994-08-31
NZ245091A (en) 1994-03-25
DE69220808T2 (de) 1998-01-02
IL103711A0 (en) 1993-04-04
JPH07500991A (ja) 1995-02-02
AU2909992A (en) 1993-06-15
ATE155045T1 (de) 1997-07-15
AU664214B2 (en) 1995-11-09
US5533995A (en) 1996-07-09
EP0612258B1 (en) 1997-07-09
CA2123428A1 (en) 1993-05-27
ZA928689B (en) 1993-05-10
WO1993009842A1 (en) 1993-05-27

Similar Documents

Publication Publication Date Title
IL103711A (en) Transdermal drug delivery device
ZA919794B (en) Skin electrode construction and transdermal drug delivery device utilizing same
ATE177325T1 (de) Transdermales system
KR930700181A (ko) 2단계 전달 프로파일을 갖는 전리요법적 약물 전달계
NO972498D0 (no) Anordning for avgivelse av aktive midler ved elektrotransport
ES2012944A6 (es) Procedimiento y su dispositivo para la admionistracion de farmacos mediante ionoforesis, para tratamiento loco-regionales.
ZA922298B (en) Device for reducing sensation during iontophoretic drug delivery
ATE194296T1 (de) Vorrichtung zur transdermalen abgabe von medikamenten durch iontophorese
NO941255D0 (no) Innretning for administrering av medikament transdermalt med en styrt temporal endring i hudström
AU5541594A (en) Vaginal sponge delivery system
EP0246715A3 (en) Apparatus for the safe delivery of a beneficial agent to a patient
DK0789589T3 (da) Sammensætning, anordning og fremgangsmåde til elektrotransport-middeltilförsel
IL119164A0 (en) Iontophoretic treatment system
DE69512083D1 (de) Vorrichtung zur erhöhung der wirkstoffsverabreichung durch elektrotransport
GR3003289T3 (en) Drug-containing plaster of the sustained-release type
ATE361772T1 (de) Behalter zur iontophoretischen verabreichung von medikamenten mit inerten material-bestandteilen
ZA891949B (en) Reservoir for controlled active substance delivery,apparatus containing the same,as well as method for its manufacture and use of the apparatus
FR2726769B1 (fr) Dispositif ionophoretique d'administration transdermique de medicaments et ensemble jetable formant partie d'un tel dispositif
KR900701311A (ko) 재조합 사람 α-인터페론을 병소내로 투여하여 편평세포 암을 치료하는 방법
ES2136605T3 (es) Dispositivo electrico de aplicacion transdermica de farmacos con un agente de contrarresto.
ATE36333T1 (de) Hydantoin enthaltende therapeutische mittel.
ES468750A1 (es) Un metodo para preparar una composicion veterinaria que com-prende trimetoprim y sulfaquinoxalina
GR1000433B (el) Συσκευη και μεθοδος ιοντοφορητικης απελευθερωσης φαρμακου.

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH Patent void
RH1 Patent not in force