KR900701311A - 재조합 사람 α-인터페론을 병소내로 투여하여 편평세포 암을 치료하는 방법 - Google Patents

재조합 사람 α-인터페론을 병소내로 투여하여 편평세포 암을 치료하는 방법

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Publication number
KR900701311A
KR900701311A KR1019900701665A KR900701665A KR900701311A KR 900701311 A KR900701311 A KR 900701311A KR 1019900701665 A KR1019900701665 A KR 1019900701665A KR 900701665 A KR900701665 A KR 900701665A KR 900701311 A KR900701311 A KR 900701311A
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KR
South Korea
Prior art keywords
interferon
recombinant human
squamous cell
cell carcinoma
intralesionally
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Application number
KR1019900701665A
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English (en)
Other versions
KR950011889B1 (ko
Inventor
제이. 텐너 다니엘
에이. 피츠 에드윈
에이. 스마일스 케니스
Original Assignee
스타이나 브이, 칸스타드
쉐링 코포레이션
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Publication of KR900701311A publication Critical patent/KR900701311A/ko
Application granted granted Critical
Publication of KR950011889B1 publication Critical patent/KR950011889B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

내용 없음

Description

재조합 사람 α-인터페론을 병소내로 투여하여 편평세포 암을 치료하는 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 치료를 요하는 사람에게 항-편평세포 암제로서 유효한 충분량의 재조합 사람 α-2인터페론을 병소내 투여함을 특징으로 하는 사람 편평세포 암을 치료하는 방법.
  2. 제1항에 있어서, α-2인터페론이 재조합 사람 인터페론 α-2b인 방법.
  3. 제1항 또는 제2항에 있어서, 매회 주입량으로 0.1 내지 10*106국제단위의 재조합 사람 α-2 인터페론을 투여하여 치료하는 방법.
  4. 제1항, 제2항 및 제3항중 어느 한 항에 있어서, 주입용량이 1.5*106국제단위인 방법
  5. 제1항, 제2항, 제3항 및 제4항중 어느 한 항에 있어서, 주입용량이 1.5*106국제단위를 주당 3일씩 3주간 투여하는 방법.
  6. 편평세포 암의 병소내적 치료용 약제를 제조하기 위한 재조합 사람 α-2 인터페론의 용도.
  7. 편평세포 암을 병소내적으로 치료하기 위한 재조합 사람 α-2인터페론의 용도.
  8. 편평세포암을 병소내적으로 치료하는데 사용하기 위한 재조합 사람 α-2인터페론을 함유하는 약학적 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900701665A 1988-12-01 1989-11-29 정제된 재조합 사람 α-2 인터페론을 포함하는, 편평세포암 치료에 유용한 병소내 투여용 약제학적 조성물 KR950011889B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27831588A 1988-12-01 1988-12-01
US278,315 1988-12-01
US88-278,315 1988-12-01
PCT/US1989/005287 WO1990006135A1 (en) 1988-12-01 1989-11-29 Treatment of squamous cell carcinoma intralesionally with recombinant human alpha interferon

Publications (2)

Publication Number Publication Date
KR900701311A true KR900701311A (ko) 1990-12-01
KR950011889B1 KR950011889B1 (ko) 1995-10-12

Family

ID=23064525

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900701665A KR950011889B1 (ko) 1988-12-01 1989-11-29 정제된 재조합 사람 α-2 인터페론을 포함하는, 편평세포암 치료에 유용한 병소내 투여용 약제학적 조성물

Country Status (14)

Country Link
EP (2) EP0372809B1 (ko)
JP (1) JPH0647556B2 (ko)
KR (1) KR950011889B1 (ko)
AT (1) ATE92333T1 (ko)
AU (1) AU634511B2 (ko)
CA (1) CA2004202C (ko)
DE (1) DE68908119T2 (ko)
DK (1) DK103891D0 (ko)
ES (1) ES2058555T3 (ko)
IE (1) IE63121B1 (ko)
IL (1) IL92495A (ko)
MY (1) MY107071A (ko)
WO (1) WO1990006135A1 (ko)
ZA (1) ZA899113B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992010207A1 (en) * 1990-12-14 1992-06-25 Schering Corporation Oral administration of alpha interferon to treat lung malignancies
IL100415A0 (en) * 1990-12-21 1992-09-06 Schering Corp Administering alpha interferon by oral inhalation to treat asthma and non-malignant proliferative pulmonary diseases
ATE229343T1 (de) * 1995-10-04 2002-12-15 Schering Corp Kombination von temozolomide und alpha-interferon zur behandlung von fortgeschrittenem krebs
US7294332B2 (en) 1995-10-04 2007-11-13 Schering Corporation Combination therapy (temozolomide and α-IFN) for advanced cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3278234D1 (en) * 1981-10-13 1988-04-21 Exovir Inc Interferon-containing compositions and the use of these compositions in the treatment of herpetic infections, pre-malignant skin lesions, skin malignancies and psoriasis
PH26198A (en) * 1986-05-27 1992-03-18 Schering Corp Treatment of basal cell carcinoma intralesionally with recombinant human alpha interferon

Also Published As

Publication number Publication date
JPH04500678A (ja) 1992-02-06
IL92495A (en) 1995-05-26
ATE92333T1 (de) 1993-08-15
IL92495A0 (en) 1990-08-31
EP0372809B1 (en) 1993-08-04
WO1990006135A1 (en) 1990-06-14
AU634511B2 (en) 1993-02-25
DK103891A (da) 1991-05-31
IE63121B1 (en) 1995-03-22
ES2058555T3 (es) 1994-11-01
ZA899113B (en) 1990-08-29
MY107071A (en) 1995-09-30
AU4802590A (en) 1990-06-26
EP0372809A1 (en) 1990-06-13
KR950011889B1 (ko) 1995-10-12
DE68908119T2 (de) 1993-11-18
CA2004202C (en) 2001-02-13
IE893828L (en) 1990-06-01
CA2004202A1 (en) 1990-06-01
EP0446279A1 (en) 1991-09-18
DK103891D0 (da) 1991-05-31
DE68908119D1 (de) 1993-09-09
JPH0647556B2 (ja) 1994-06-22

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