|
US5976832A
(en)
*
|
1995-03-06 |
1999-11-02 |
Tonen Corporation |
DNA encoding novel calcium-binding proteins
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
SI0907735T2
(sl)
*
|
1996-05-24 |
2010-01-29 |
Biogen Idec Inc |
Modulatorji tkivne regeneracije
|
|
US6991790B1
(en)
|
1997-06-13 |
2006-01-31 |
Genentech, Inc. |
Antibody formulation
|
|
US6171586B1
(en)
*
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
DK1068238T3
(da)
|
1998-04-02 |
2013-01-14 |
Xintela Ab |
Integrinheterodimer og subunit deraf
|
|
US20030055231A1
(en)
*
|
1998-10-28 |
2003-03-20 |
Jian Ni |
12 human secreted proteins
|
|
US7883704B2
(en)
*
|
1999-03-25 |
2011-02-08 |
Abbott Gmbh & Co. Kg |
Methods for inhibiting the activity of the P40 subunit of human IL-12
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
EP1174509A4
(en)
*
|
1999-03-29 |
2003-10-22 |
Kansai Tech Licensing Org Co |
cytidine deaminase
|
|
EP2264166B1
(en)
|
1999-04-09 |
2016-03-23 |
Kyowa Hakko Kirin Co., Ltd. |
Method for controlling the activity of immunologically functional molecule
|
|
SE9902056D0
(sv)
*
|
1999-06-03 |
1999-06-03 |
Active Biotech Ab |
An integrin heterodimer and an alpha subunit thereof
|
|
US6808902B1
(en)
*
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
|
US20020035107A1
(en)
*
|
2000-06-20 |
2002-03-21 |
Stefan Henke |
Highly concentrated stable meloxicam solutions
|
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
|
US20020141970A1
(en)
*
|
2001-03-05 |
2002-10-03 |
Pettit Dean K. |
Stable aqueous solutions of granulocyte macrophage colony-stimulating factor
|
|
PL366469A1
(en)
*
|
2001-04-05 |
2005-02-07 |
Immuno-Biological Laboratories Co, Ltd. |
Anti-osteopontin antibody and use thereof
|
|
PT1475101E
(pt)
*
|
2002-02-14 |
2010-12-22 |
Chugai Pharmaceutical Co Ltd |
Fármacos em solução contendo anticorpos
|
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
|
JP5116971B2
(ja)
|
2002-10-15 |
2013-01-09 |
インターセル アーゲー |
B群連鎖球菌の接着因子をコードする核酸、b群連鎖球菌の接着因子、およびその使用
|
|
MY150740A
(en)
|
2002-10-24 |
2014-02-28 |
Abbvie Biotechnology Ltd |
Low dose methods for treating disorders in which tnf? activity is detrimental
|
|
EP1652925B1
(en)
|
2003-07-15 |
2010-12-08 |
Chugai Seiyaku Kabushiki Kaisha |
IgM PRODUCTION BY TRANSFORMED CELLS AND METHODS FOR QUANTIFYING SAID IgM PRODUCTION
|
|
CA2540848C
(en)
|
2003-10-01 |
2012-12-11 |
Kyowa Kirin Co., Ltd. |
Method for stabilizing antibody and stabilized solution-type antibody preparation
|
|
US7803914B2
(en)
|
2003-10-09 |
2010-09-28 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for stabilizing protein solutions
|
|
EP1688432B1
(en)
*
|
2003-10-09 |
2011-08-03 |
Chugai Seiyaku Kabushiki Kaisha |
Igm high concentration stabilized solution
|
|
JPWO2005063291A1
(ja)
*
|
2003-12-25 |
2007-07-19 |
麒麟麦酒株式会社 |
抗体を含有する安定な水性医薬製剤
|
|
EP1568369A1
(en)
|
2004-02-23 |
2005-08-31 |
Boehringer Ingelheim Vetmedica Gmbh |
Use of meloxicam for the treatment of respiratory diseases in pigs
|
|
AU2005229457B2
(en)
|
2004-03-30 |
2010-11-25 |
Glaxo Group Limited |
Immunoglobulins
|
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
|
ES2707284T3
(es)
*
|
2005-03-08 |
2019-04-03 |
Pfizer Prod Inc |
Composiciones de anticuerpo anti-CTLA-4
|
|
AU2006247039B2
(en)
*
|
2005-05-19 |
2011-03-03 |
Amgen Inc. |
Compositions and methods for increasing the stability of antibodies
|
|
SG162788A1
(en)
|
2005-06-14 |
2010-07-29 |
Amgen Inc |
Self-buffering protein formulations
|
|
AR059066A1
(es)
|
2006-01-27 |
2008-03-12 |
Amgen Inc |
Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf)
|
|
US20110008282A1
(en)
*
|
2006-05-15 |
2011-01-13 |
Xbiotech, Inc. |
IL-1alpha immunization induces autoantibodies protective against atherosclerosis
|
|
ES2374845T3
(es)
*
|
2006-05-22 |
2012-02-22 |
Xbiotech, Inc |
Tratamiento de cáncer con anticuerpos anti-il-1.
|
|
JP5631591B2
(ja)
*
|
2006-10-06 |
2014-11-26 |
アムジエン・インコーポレーテツド |
安定な抗体製剤
|
|
ES2925992T3
(es)
*
|
2006-10-20 |
2022-10-20 |
Amgen Inc |
Formulaciones estables de polipéptidos
|
|
US7776331B1
(en)
|
2007-01-16 |
2010-08-17 |
Abbott Laboratories |
Methods of treating plaque psoriasis
|
|
NZ580379A
(en)
|
2007-03-29 |
2012-10-26 |
Abbott Lab |
Crystalline anti-human il-12 antibodies
|
|
US8883146B2
(en)
|
2007-11-30 |
2014-11-11 |
Abbvie Inc. |
Protein formulations and methods of making same
|
|
TWI461210B
(zh)
*
|
2008-03-18 |
2014-11-21 |
Abbvie Inc |
治療牛皮癬的方法
|
|
HUE029003T2
(en)
*
|
2008-05-30 |
2017-01-30 |
Xbiotech Inc |
IL-1 alpha antibodies
|
|
AU2009291536B2
(en)
*
|
2008-09-12 |
2012-08-16 |
Xbiotech Inc. |
Targeting pathogenic monocytes
|
|
AU2009319856A1
(en)
*
|
2008-11-28 |
2010-06-03 |
Abbvie Inc. |
Stable antibody compositions and methods for stabilizing same
|
|
AR074777A1
(es)
|
2008-12-19 |
2011-02-09 |
Glaxo Group Ltd |
Proteinas de union a antigeno
|
|
GB0904355D0
(en)
*
|
2009-03-13 |
2009-04-29 |
Imp Innovations Ltd |
Biological materials and uses thereof
|
|
CA2760185A1
(en)
*
|
2009-05-04 |
2010-11-11 |
Abbott Biotechnology Ltd. |
Stable high protein concentration formulations of human anti-tnf-alpha antibodies
|
|
MX2012003138A
(es)
*
|
2009-09-14 |
2012-07-04 |
Abbott Lab Y Abbott Gmbh & Co Kg |
Metodos para tratar la psoriasis.
|
|
WO2011038069A1
(en)
*
|
2009-09-24 |
2011-03-31 |
Xbiotech, Inc. |
Methods, compositions, and kits for reducing anti-antibody responses
|
|
WO2011049082A1
(ja)
*
|
2009-10-21 |
2011-04-28 |
国立大学法人広島大学 |
インテグリンα8β1特異的モノクローナル抗体
|
|
KR20130028055A
(ko)
|
2010-01-28 |
2013-03-18 |
글락소 그룹 리미티드 |
Cd 127 결합 단백질
|
|
KR20120133382A
(ko)
|
2010-02-09 |
2012-12-10 |
글락소 그룹 리미티드 |
대사 장애의 치료
|
|
KR20190047135A
(ko)
|
2010-03-01 |
2019-05-07 |
바이엘 헬스케어 엘엘씨 |
조직 인자 경로 억제제 (tfpi)에 대한 최적화된 모노클로날 항체
|
|
UA108227C2
(xx)
|
2010-03-03 |
2015-04-10 |
|
Антигензв'язуючий білок
|
|
UY33421A
(es)
|
2010-06-03 |
2011-12-30 |
Glaxo Wellcome House |
Proteinas de union al antígeno humanizados
|
|
DK2582391T3
(da)
|
2010-06-18 |
2019-01-21 |
Xbiotech Inc |
Arthritis-behandling
|
|
WO2012027324A2
(en)
|
2010-08-23 |
2012-03-01 |
Xbiotech, Inc. |
Treatment for neoplastic diseases
|
|
EP2444101A1
(en)
|
2010-10-21 |
2012-04-25 |
Universitätsklinikum Freiburg |
Selective targeting of the CD40L/Mac-1 interaction by small peptide inhibitors and its use for the treatment of inflammation and atherogenesis
|
|
ES2601202T3
(es)
|
2010-11-11 |
2017-02-14 |
Abbvie Biotechnology Ltd |
Formulaciones liquidas de anticuerpos anti-TNT-alfa de alta concentración
|
|
US9724409B2
(en)
|
2011-04-01 |
2017-08-08 |
Xbiotech, Inc. |
Treatment of inflammatory skin disease
|
|
EP2702077A2
(en)
|
2011-04-27 |
2014-03-05 |
AbbVie Inc. |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
|
AU2012312225B2
(en)
|
2011-09-23 |
2017-10-05 |
Xbiotech Inc. |
Cachexia treatment
|
|
US9895437B2
(en)
|
2012-04-18 |
2018-02-20 |
Valneva Austria Gmbh |
Aluminum compounds for use in therapeutics and vaccines
|
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
|
US9334319B2
(en)
|
2012-04-20 |
2016-05-10 |
Abbvie Inc. |
Low acidic species compositions
|
|
US9181572B2
(en)
|
2012-04-20 |
2015-11-10 |
Abbvie, Inc. |
Methods to modulate lysine variant distribution
|
|
US9249182B2
(en)
|
2012-05-24 |
2016-02-02 |
Abbvie, Inc. |
Purification of antibodies using hydrophobic interaction chromatography
|
|
US8883979B2
(en)
|
2012-08-31 |
2014-11-11 |
Bayer Healthcare Llc |
Anti-prolactin receptor antibody formulations
|
|
US9592297B2
(en)
|
2012-08-31 |
2017-03-14 |
Bayer Healthcare Llc |
Antibody and protein formulations
|
|
US8613919B1
(en)
|
2012-08-31 |
2013-12-24 |
Bayer Healthcare, Llc |
High concentration antibody and protein formulations
|
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
|
KR20150043523A
(ko)
|
2012-09-02 |
2015-04-22 |
애브비 인코포레이티드 |
단백질 불균일성의 제어 방법
|
|
US9545441B2
(en)
|
2012-09-18 |
2017-01-17 |
Xbiotech, Inc. |
Treatment of diabetes
|
|
WO2014143205A1
(en)
|
2013-03-12 |
2014-09-18 |
Abbvie Inc. |
Human antibodies that bind human tnf-alpha and methods of preparing the same
|
|
US8921526B2
(en)
|
2013-03-14 |
2014-12-30 |
Abbvie, Inc. |
Mutated anti-TNFα antibodies and methods of their use
|
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
|
US10081673B2
(en)
*
|
2013-03-14 |
2018-09-25 |
Ffe Therapeutics Llc |
Compositions and methods for treating angiogenesis-related disorders
|
|
US9499614B2
(en)
|
2013-03-14 |
2016-11-22 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
|
|
WO2015051293A2
(en)
|
2013-10-04 |
2015-04-09 |
Abbvie, Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
|
US20150139988A1
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
|
WO2016059602A2
(en)
|
2014-10-16 |
2016-04-21 |
Glaxo Group Limited |
Methods of treating cancer and related compositions
|
|
EP4470648A3
(en)
|
2015-08-13 |
2025-03-05 |
Amgen Inc. |
Charged depth filtration of antigen-binding proteins
|
|
WO2017049529A1
(en)
|
2015-09-24 |
2017-03-30 |
Innolife Co., Ltd. |
A pharmaceutical composition comprising a copper chelating tetramine and the use thereof
|
|
CA3053231A1
(en)
|
2017-02-16 |
2018-08-23 |
Xbiotech Inc. |
Treatment of hidradenitis suppurativa
|
|
CN110408600A
(zh)
*
|
2018-12-10 |
2019-11-05 |
浙江工商大学 |
一株分泌抗重金属铜离子单克隆抗体的杂交瘤细胞株及其应用
|
|
CA3095676A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleukin 1 alpha (il-1a)
|
|
CA3095740A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleukin alpha (il-1a)
|
|
CA3095675A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleukin 1 alpha (il-1a)
|
|
CA3095679A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleuken 1 alpha (il-1a)
|