CN112543647A - 一种tim3抗体药物组合物及其用途 - Google Patents
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Abstract
本发明公开了一种TIM3抗体药物组合物及其用途。具体而言,所述药物组合物包含在缓冲液中的TIM3抗体或其抗原结合片段。除此之外,该药物组合物还包含糖和非离子型表面活性剂。本发明中的药物组合物具备良好的稳定性。
Description
PCT国内申请,说明书已公开。
Claims (25)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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CN2018109871383 | 2018-08-28 | ||
CN201810987138 | 2018-08-28 | ||
PCT/CN2019/102839 WO2020043095A1 (zh) | 2018-08-28 | 2019-08-27 | 一种tim3抗体药物组合物及其用途 |
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CN112543647A true CN112543647A (zh) | 2021-03-23 |
CN112543647B CN112543647B (zh) | 2024-04-16 |
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CN201980049906.3A Active CN112543647B (zh) | 2018-08-28 | 2019-08-27 | 一种tim3抗体药物组合物及其用途 |
Country Status (9)
Country | Link |
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US (1) | US20210261663A1 (zh) |
EP (1) | EP3848049A4 (zh) |
JP (1) | JP2022513553A (zh) |
KR (1) | KR20210053294A (zh) |
CN (1) | CN112543647B (zh) |
AU (1) | AU2019330702A1 (zh) |
CA (1) | CA3110002A1 (zh) |
TW (1) | TW202009241A (zh) |
WO (1) | WO2020043095A1 (zh) |
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CN114632156A (zh) * | 2022-05-17 | 2022-06-17 | 中国人民解放军军事科学院军事医学研究院 | Tim-3在预防、治疗或减轻疼痛中的应用 |
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WO2021175191A1 (zh) * | 2020-03-02 | 2021-09-10 | 信达生物制药(苏州)有限公司 | 抗tim-3抗体及其用途 |
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CN107001475A (zh) * | 2014-11-06 | 2017-08-01 | 豪夫迈·罗氏有限公司 | 抗tim3抗体及使用方法 |
CN109983032A (zh) * | 2017-02-27 | 2019-07-05 | 江苏恒瑞医药股份有限公司 | Tim-3抗体、其抗原结合片段及医药用途 |
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AU2011262758B8 (en) * | 2010-06-11 | 2014-09-04 | Kyowa Kirin Co., Ltd. | Anti-tim-3 antibody |
US9163087B2 (en) | 2010-06-18 | 2015-10-20 | The Brigham And Women's Hospital, Inc. | Bi-specific antibodies against TIM-3 and PD-1 for immunotherapy in chronic immune conditions |
WO2013006490A2 (en) | 2011-07-01 | 2013-01-10 | Cellerant Therapeutics, Inc. | Antibodies that specifically bind to tim3 |
JOP20200096A1 (ar) | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
US20160200815A1 (en) * | 2015-01-05 | 2016-07-14 | Jounce Therapeutics, Inc. | Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof |
TW201639888A (zh) | 2015-03-06 | 2016-11-16 | 索倫多醫療公司 | 結合tim3之抗體治療劑 |
MA41867A (fr) | 2015-04-01 | 2018-02-06 | Anaptysbio Inc | Anticorps dirigés contre l'immunoglobuline de cellule t et protéine 3 de mucine (tim-3) |
US11014983B2 (en) * | 2015-08-20 | 2021-05-25 | Sutro Biopharma, Inc. | Anti-Tim-3 antibodies, compositions comprising anti-Tim-3 antibodies and methods of making and using anti-Tim-3 antibodies |
JOP20190013A1 (ar) * | 2016-08-25 | 2019-01-31 | Lilly Co Eli | أجسام مضادة لـ (تي آي ام -3) |
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- 2019-08-27 CA CA3110002A patent/CA3110002A1/en active Pending
- 2019-08-27 WO PCT/CN2019/102839 patent/WO2020043095A1/zh unknown
- 2019-08-27 CN CN201980049906.3A patent/CN112543647B/zh active Active
- 2019-08-27 EP EP19855752.2A patent/EP3848049A4/en not_active Withdrawn
- 2019-08-27 AU AU2019330702A patent/AU2019330702A1/en not_active Abandoned
- 2019-08-27 KR KR1020217006876A patent/KR20210053294A/ko unknown
- 2019-08-27 US US17/269,456 patent/US20210261663A1/en active Pending
- 2019-08-28 TW TW108130836A patent/TW202009241A/zh unknown
Patent Citations (2)
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CN107001475A (zh) * | 2014-11-06 | 2017-08-01 | 豪夫迈·罗氏有限公司 | 抗tim3抗体及使用方法 |
CN109983032A (zh) * | 2017-02-27 | 2019-07-05 | 江苏恒瑞医药股份有限公司 | Tim-3抗体、其抗原结合片段及医药用途 |
Cited By (1)
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CN114632156A (zh) * | 2022-05-17 | 2022-06-17 | 中国人民解放军军事科学院军事医学研究院 | Tim-3在预防、治疗或减轻疼痛中的应用 |
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US20210261663A1 (en) | 2021-08-26 |
JP2022513553A (ja) | 2022-02-09 |
WO2020043095A1 (zh) | 2020-03-05 |
CN112543647B (zh) | 2024-04-16 |
EP3848049A1 (en) | 2021-07-14 |
CA3110002A1 (en) | 2020-03-05 |
AU2019330702A1 (en) | 2021-04-08 |
EP3848049A4 (en) | 2022-05-18 |
KR20210053294A (ko) | 2021-05-11 |
TW202009241A (zh) | 2020-03-01 |
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