IL103007A - Condensed (hetero)cyclic amine derivatives and their preparation - Google Patents

Condensed (hetero)cyclic amine derivatives and their preparation

Info

Publication number
IL103007A
IL103007A IL103007A IL10300787A IL103007A IL 103007 A IL103007 A IL 103007A IL 103007 A IL103007 A IL 103007A IL 10300787 A IL10300787 A IL 10300787A IL 103007 A IL103007 A IL 103007A
Authority
IL
Israel
Prior art keywords
hetero
condensed
preparation
cyclic amine
amine derivatives
Prior art date
Application number
IL103007A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL103007A publication Critical patent/IL103007A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL103007A 1986-01-16 1987-01-15 Condensed (hetero)cyclic amine derivatives and their preparation IL103007A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82047186A 1986-01-16 1986-01-16

Publications (1)

Publication Number Publication Date
IL103007A true IL103007A (en) 1993-07-08

Family

ID=25230864

Family Applications (2)

Application Number Title Priority Date Filing Date
IL81268A IL81268A0 (en) 1986-01-16 1987-01-15 Fused benzazepines,process for preparing them and pharmaceutical compositions containing them
IL103007A IL103007A (en) 1986-01-16 1987-01-15 Condensed (hetero)cyclic amine derivatives and their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL81268A IL81268A0 (en) 1986-01-16 1987-01-15 Fused benzazepines,process for preparing them and pharmaceutical compositions containing them

Country Status (19)

Country Link
EP (2) EP0254737B1 (fi)
JP (1) JPH0681745B2 (fi)
KR (1) KR900007781B1 (fi)
AU (1) AU588080B2 (fi)
CA (1) CA1333485C (fi)
CS (1) CS414091A3 (fi)
DK (1) DK164161C (fi)
ES (1) ES2031834T3 (fi)
FI (1) FI83512C (fi)
GR (1) GR3000994T3 (fi)
HU (1) HU199805B (fi)
IE (1) IE59651B1 (fi)
IL (2) IL81268A0 (fi)
NZ (1) NZ218953A (fi)
OA (1) OA08660A (fi)
PT (1) PT84109B (fi)
SG (1) SG128692G (fi)
WO (1) WO1987004430A2 (fi)
ZA (1) ZA87291B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973586A (en) 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
HU203537B (en) * 1987-07-15 1991-08-28 Schering Corp Process for producing condensed benzazepine derivatives and pharmaceutical compositions containing them
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
AU624854B2 (en) * 1988-07-29 1992-06-25 Schering Corporation A process for the enantiospecific synthesis of intermediates for hexahydro-benzo(d)naphtho(2,1-b)azepines
US5104814A (en) * 1988-11-22 1992-04-14 Schering Corporation Assay kit and methods for neuroleptic drugs
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
CA2075181C (en) * 1990-02-02 1997-12-09 Theodros Asberom 4,5-bridged-2,3,4,5-tetrahydro-1h-3-benzazepine-7-ols
US5463051A (en) * 1993-09-27 1995-10-31 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461147A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461148A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
AR027687A1 (es) * 2000-03-22 2003-04-09 Yakult Honsha Kk Procedimiento para preparar camptotecina
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
CN1688584A (zh) * 2002-08-29 2005-10-26 先灵公司 治疗肥胖和中枢神经系统疾病的选择性d1/d5受体拮抗剂
MXPA05012572A (es) * 2003-05-22 2006-02-08 Schering Corp Derivado de 5-h-benzo[d]naft[2,1-b]azepina como antagonistas selectivos del receptor d1/d5 para el tratamiento de la obesidad y trastornos del sistema nervioso central.
WO2008156707A1 (en) * 2007-06-15 2008-12-24 University Of Florida Research Foundation Therapeutic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
GB1118688A (en) 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
US3609138A (en) 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines
FR2137627A1 (fi) * 1971-05-10 1972-12-29 Hoffmann La Roche
US3939165A (en) * 1974-11-14 1976-02-17 Morton-Norwich Products, Inc. 5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en) 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en) 1979-04-27 1981-08-18 Schering Corporation 7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en) 1980-02-05 1984-10-16 Schering Corp. Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
HU199805B (en) 1990-03-28
JPH0681745B2 (ja) 1994-10-19
WO1987004430A3 (en) 1988-03-24
DK479087A (da) 1987-09-14
EP0230270A3 (en) 1987-10-21
DK164161B (da) 1992-05-18
SG128692G (en) 1993-03-12
AU588080B2 (en) 1989-09-07
CA1333485C (en) 1994-12-13
EP0230270A2 (en) 1987-07-29
ES2031834T3 (es) 1993-01-01
KR900007781B1 (ko) 1990-10-20
EP0254737A1 (en) 1988-02-03
IL81268A0 (en) 1987-08-31
EP0254737B1 (en) 1990-07-25
FI874006A0 (fi) 1987-09-15
AU6892087A (en) 1987-08-14
FI83512B (fi) 1991-04-15
JPS63502348A (ja) 1988-09-08
KR880700794A (ko) 1988-04-12
FI83512C (fi) 1991-07-25
NZ218953A (en) 1990-03-27
OA08660A (en) 1988-11-30
FI874006A (fi) 1987-09-15
IE59651B1 (en) 1994-03-09
CS414091A3 (en) 1992-05-13
DK164161C (da) 1992-10-26
IE870112L (en) 1987-07-16
DK479087D0 (da) 1987-09-14
HUT48600A (en) 1989-06-28
PT84109B (pt) 1989-07-31
PT84109A (en) 1987-02-01
ZA87291B (en) 1987-11-25
GR3000994T3 (en) 1991-12-10
WO1987004430A2 (en) 1987-07-30
EP0230270B1 (en) 1990-08-01

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Legal Events

Date Code Title Description
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees