IL102175A0 - Imidazodiazepine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Imidazodiazepine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL102175A0 IL102175A0 IL102175A IL10217592A IL102175A0 IL 102175 A0 IL102175 A0 IL 102175A0 IL 102175 A IL102175 A IL 102175A IL 10217592 A IL10217592 A IL 10217592A IL 102175 A0 IL102175 A0 IL 102175A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- imidazodiazepine derivatives
- imidazodiazepine
- Prior art date
Links
- BMGXAZCDDYTVFV-UHFFFAOYSA-N imidazo[4,5-c]diazepine Chemical class C1=CN=NC2=NC=NC2=C1 BMGXAZCDDYTVFV-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH179191 | 1991-06-17 | ||
| CH114092 | 1992-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL102175A0 true IL102175A0 (en) | 1993-01-14 |
Family
ID=25686778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL102175A IL102175A0 (en) | 1991-06-17 | 1992-06-11 | Imidazodiazepine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5387585A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0519307A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JPH078869B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR930000517A (cg-RX-API-DMAC7.html) |
| AU (1) | AU655472B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2069382A1 (cg-RX-API-DMAC7.html) |
| CZ (1) | CZ185092A3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI922827A7 (cg-RX-API-DMAC7.html) |
| HU (1) | HU9201929D0 (cg-RX-API-DMAC7.html) |
| IE (1) | IE921945A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL102175A0 (cg-RX-API-DMAC7.html) |
| IS (1) | IS3878A (cg-RX-API-DMAC7.html) |
| NO (1) | NO922367L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ243091A (cg-RX-API-DMAC7.html) |
| TW (1) | TW201311B (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW349100B (en) * | 1994-11-11 | 1999-01-01 | Hoffmann La Roche | Oxazolyl- and thiazolylimidazo-benzo- and thienodiazepines |
| JPH10298078A (ja) * | 1997-05-06 | 1998-11-10 | Mitsubishi Chem Corp | 抗不安薬 |
| TWI239333B (en) * | 2000-11-16 | 2005-09-11 | Hoffmann La Roche | Benzodiazepine derivatives as GABA A receptor modulators |
| US6686352B2 (en) * | 2001-05-18 | 2004-02-03 | Hoffmann-La Roche Inc. | Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives |
| HU230352B1 (hu) * | 2001-06-12 | 2016-02-29 | Wellstat Therapeutics Corporation | Metabolikus rendellenességek kezelésére adható vegyületek és ezeket tartalmazó gyógyászati készítmények |
| AU2005293820B2 (en) | 2004-10-12 | 2010-11-25 | F. Hoffmann-La Roche Ag | Imidazo [1, 5-a]triazolo[1, 5-d]benzodiazepine derivatives for the treatment of cognitive disorders |
| RU2007114763A (ru) * | 2004-10-20 | 2008-11-27 | Ф.Хоффманн-Ля Рош Аг (Ch) | Галогенозамещенные производные бензодиазепинов |
| CA2584259C (en) * | 2004-10-20 | 2013-04-02 | F. Hoffmann-La Roche Ag | Imidazo-benzodiazepine derivatives |
| EP1828194B1 (en) | 2004-12-14 | 2008-05-28 | F. Hoffmann-Roche AG | Tetracyclic imidazo-benzodiazepines as gaba receptors modulators |
| BRPI0617204A2 (pt) | 2005-10-11 | 2011-07-19 | Hoffmann La Roche | derivados de imidazo benzodiazepina |
| AU2014240289B2 (en) * | 2008-09-23 | 2015-12-03 | The Johns Hopkins University | Fused diimidazodiazepine compounds and methods of use and manufacture thereof |
| CA2738650C (en) | 2008-09-23 | 2017-07-04 | Johns Hopkins University | Fused diimidazodiazepine compounds and methods of use and manufacture thereof |
| US9322831B2 (en) | 2008-09-23 | 2016-04-26 | The Johns Hopkins University | DDX3 as a biomarker for cancer and methods related thereto |
| CA2818025A1 (en) | 2010-11-15 | 2012-05-24 | Agenebio, Inc. | Pyridazine derivatives, compositions and methods for treating cognitive impairment |
| HUE048874T2 (hu) | 2013-09-06 | 2020-08-28 | Aurigene Discovery Tech Ltd | 1,2,4-oxadiazol-származékok, mint immunmodulátorok |
| EP4032889A1 (en) * | 2013-12-20 | 2022-07-27 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| CA2979161A1 (en) * | 2015-03-10 | 2016-09-15 | Aurigene Discovery Technologies Limited | 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| AU2016230793B2 (en) | 2015-03-10 | 2021-03-25 | Aurigene Discovery Technologies Limited | 1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| CA2990004C (en) | 2015-06-19 | 2024-04-23 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| CA3008171A1 (en) | 2015-12-22 | 2017-06-29 | SHY Therapeutics LLC | Compounds for the treatment of cancer and inflammatory disease |
| BR112019012821A2 (pt) | 2016-12-19 | 2019-11-26 | Agenebio, Inc. | derivados de benzodiazepina, composições e métodos para o tratamento do comprometimento cognitivo |
| US20180170941A1 (en) * | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| WO2018237084A1 (en) | 2017-06-21 | 2018-12-27 | SHY Therapeutics LLC | COMPOUNDS INTERACTING WITH RAS SUPERFAMIL FOR USE IN THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES AND FIBROTIC DISEASES |
| WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
| EP3694841A1 (en) | 2017-10-11 | 2020-08-19 | Aurigene Discovery Technologies Limited | Crystalline forms of 3-substituted 1,2,4-oxadiazole |
| MX2020004531A (es) | 2017-11-03 | 2020-08-03 | Aurigene Discovery Tech Ltd | Inhibidores dobles de tim-3 y las vias de pd-1. |
| EP3706798A1 (en) | 2017-11-06 | 2020-09-16 | Aurigene Discovery Technologies Limited | Conjoint therapies for immunomodulation |
| AU2019288382B2 (en) | 2018-06-19 | 2024-07-25 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| JP7407461B2 (ja) | 2018-12-19 | 2024-01-04 | シャイ・セラピューティクス・エルエルシー | がん、炎症性疾患、ｒａｓ病、及び線維性疾患の処置のためのｒａｓスーパーファミリーと相互作用する化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1143728A (en) * | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| ATE110726T1 (de) * | 1984-01-19 | 1994-09-15 | Hoffmann La Roche | Imidazodiazepin-derivate. |
| US4897392A (en) * | 1989-07-03 | 1990-01-30 | Hoechst-Roussel Pharmaceuticals, Inc. | 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines |
| DK443589D0 (da) * | 1989-09-08 | 1989-09-08 | Ferrosan As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| DK41191D0 (da) * | 1991-03-07 | 1991-03-07 | Novo Nordisk As | Heterocycliske forbindelser, deres fremstilling og anvendelse |
-
1992
- 1992-05-15 TW TW081103807A patent/TW201311B/zh active
- 1992-05-25 CA CA002069382A patent/CA2069382A1/en not_active Abandoned
- 1992-06-10 HU HU9201929A patent/HU9201929D0/hu unknown
- 1992-06-10 NZ NZ243091A patent/NZ243091A/en unknown
- 1992-06-10 EP EP19920109745 patent/EP0519307A3/de not_active Withdrawn
- 1992-06-11 IL IL102175A patent/IL102175A0/xx unknown
- 1992-06-12 AU AU18234/92A patent/AU655472B2/en not_active Ceased
- 1992-06-12 JP JP4179406A patent/JPH078869B2/ja not_active Expired - Lifetime
- 1992-06-12 IS IS3878A patent/IS3878A/is unknown
- 1992-06-16 CZ CS921850A patent/CZ185092A3/cs unknown
- 1992-06-16 NO NO92922367A patent/NO922367L/no unknown
- 1992-06-16 KR KR1019920010394A patent/KR930000517A/ko not_active Withdrawn
- 1992-06-17 FI FI922827A patent/FI922827A7/fi not_active Application Discontinuation
- 1992-07-01 IE IE194592A patent/IE921945A1/en not_active Application Discontinuation
-
1993
- 1993-11-15 US US08/153,234 patent/US5387585A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI922827A0 (fi) | 1992-06-17 |
| CZ185092A3 (en) | 1993-12-15 |
| IS3878A (is) | 1992-12-18 |
| FI922827A7 (fi) | 1992-12-18 |
| NZ243091A (en) | 1994-11-25 |
| IE921945A1 (en) | 1992-12-30 |
| NO922367L (no) | 1992-12-18 |
| KR930000517A (ko) | 1993-01-15 |
| EP0519307A2 (de) | 1992-12-23 |
| EP0519307A3 (en) | 1993-04-21 |
| AU1823492A (en) | 1992-12-24 |
| JPH078869B2 (ja) | 1995-02-01 |
| TW201311B (cg-RX-API-DMAC7.html) | 1993-03-01 |
| NO922367D0 (no) | 1992-06-16 |
| US5387585A (en) | 1995-02-07 |
| JPH05202051A (ja) | 1993-08-10 |
| AU655472B2 (en) | 1994-12-22 |
| CA2069382A1 (en) | 1992-12-18 |
| HU9201929D0 (en) | 1992-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL102175A0 (en) | Imidazodiazepine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL101864A0 (en) | Thiopyranopyrrole derivatives,their preparation and pharmaceutical compositions containing them | |
| IL99225A0 (en) | 3-amidopyrazole derivatives,their preparation and pharmaceutical compositions containing them | |
| IL102638A0 (en) | Heterocyclic compounds,their preparation and pharmaceutical compositions containing them | |
| IL103053A0 (en) | Heterocyclic compounds,their preparation and pharmaceutical compositions containing them | |
| IL103198A0 (en) | Benzanilide derivatives,their preparation and pharmaceutical compositions containing them | |
| IL103197A0 (en) | Benzanilide derivatives,their preparation and pharmaceutical compositions containing them | |
| IL103199A0 (en) | Benzanilide derivatives,their preparation and pharmaceutical compositions containing them | |
| IL100262A0 (en) | Alpha-oxoacetamide derivatives,their preparation and pharmaceutical compositions containing them | |
| IL103529A0 (en) | 1,4-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL104445A0 (en) | Piperidine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL101380A0 (en) | Bis-naphthalimides,their preparation and pharmaceutical compositions containing them | |
| IL97050A0 (en) | 4-isoxazolecarboxamide derivatives,pharmaceutical compositions containing them and their preparation | |
| IL101882A0 (en) | Benzofuran derivatives,their preparation and pharmaceutical compositions containing them | |
| IL98542A0 (en) | Benzoquinazoline derivatives,their preparation and pharmaceutical compositions containing them | |
| IL101042A0 (en) | 3-piperidinyl-methylcarboxylate substituted indoles,their preparation and pharmaceutical compositions containing them | |
| IL98756A0 (en) | Pharmaceutical compositions containing benzeneacetamid derivatives,certain such novel compounds and their preparation | |
| IL108703A0 (en) | Substituted azolone derivatives, their preparation and pharmaceutical compositions containing them | |
| IL98499A0 (en) | Aminobenzodiazepines,their preparation and pharmaceutical compositions containing them | |
| IL101351A0 (en) | Benzofuran derivatives,their preparation and pharmaceutical compositions containing them | |
| IL103502A0 (en) | Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL101888A0 (en) | Benzofuran derivatives,their preparation and pharmaceutical compositions containing them | |
| IL102500A0 (en) | 3-deoxy-mannosamine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL104042A0 (en) | Substituted diphenylsulfides,their preparation and pharmaceutical compositions containing them | |
| IL105774A0 (en) | Thienothiazine derivatives,their preparation and pharmaceutical compositions containing them |