IL101425A0 - Peptides and mixtures thereof for detecting antibodies to hepatitis c virus,methods for their use and pharmaceutical compositions containing the same - Google Patents

Peptides and mixtures thereof for detecting antibodies to hepatitis c virus,methods for their use and pharmaceutical compositions containing the same

Info

Publication number
IL101425A0
IL101425A0 IL101425A IL10142592A IL101425A0 IL 101425 A0 IL101425 A0 IL 101425A0 IL 101425 A IL101425 A IL 101425A IL 10142592 A IL10142592 A IL 10142592A IL 101425 A0 IL101425 A0 IL 101425A0
Authority
IL
Israel
Prior art keywords
hepatitis
peptides
virus
mixtures
methods
Prior art date
Application number
IL101425A
Other languages
English (en)
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of IL101425A0 publication Critical patent/IL101425A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL101425A 1991-04-05 1992-03-31 Peptides and mixtures thereof for detecting antibodies to hepatitis c virus,methods for their use and pharmaceutical compositions containing the same IL101425A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/681,701 US5574132A (en) 1991-04-05 1991-04-05 Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)

Publications (1)

Publication Number Publication Date
IL101425A0 true IL101425A0 (en) 1992-11-15

Family

ID=24736406

Family Applications (1)

Application Number Title Priority Date Filing Date
IL101425A IL101425A0 (en) 1991-04-05 1992-03-31 Peptides and mixtures thereof for detecting antibodies to hepatitis c virus,methods for their use and pharmaceutical compositions containing the same

Country Status (12)

Country Link
US (1) US5574132A (ja)
EP (1) EP0507615A1 (ja)
JP (2) JP3477198B2 (ja)
CN (1) CN1051091C (ja)
AU (1) AU1447492A (ja)
CA (1) CA2107672C (ja)
EG (1) EG20096A (ja)
IE (1) IE921070A1 (ja)
IL (1) IL101425A0 (ja)
NZ (1) NZ242183A (ja)
WO (1) WO1992017493A2 (ja)
ZA (1) ZA922309B (ja)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US6312889B1 (en) 1990-04-04 2001-11-06 Chiron Corporation Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
KR930702507A (ko) * 1990-11-07 1993-09-09 챨스 엠. 브록 C형 간염 바이러스에 대한 모노클로날 항체 및 이의 사용 방법
GB9105871D0 (en) * 1991-03-20 1991-05-08 Inst Cientifico Tecnol Navarra Synthetic peptides
WO1993000365A2 (en) 1991-06-24 1993-01-07 Chiron Corporation Hepatitis c virus (hcv) polypeptides
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
WO1993011158A2 (en) * 1991-12-06 1993-06-10 Akzo Nobel N.V. Non-a, non-b peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
BR9305435A (pt) * 1992-03-06 1994-12-27 Innogenetics Nv Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
KR100312535B1 (ko) * 1993-04-30 2002-06-20 성재갑 혼합항원을이용한씨(c)형간염바이러스의항체진단방법
JPH08510240A (ja) 1993-05-12 1996-10-29 カイロン コーポレイション Ｃ型肝炎ウイルスｅ２／ｎｓ１領域の保存モチーフ
JPH07135981A (ja) * 1993-05-28 1995-05-30 Eisai Co Ltd 非ａ非ｂ型肝炎ウイルス遺伝子に由来するｄｎａ及び構成ポリペプチド
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
EP0729973A4 (en) * 1993-10-29 1998-12-30 Srl Inc AN ANTIQUE PEPTIDE COMPOUND AND IMMUNOASSAY PROCEDURE
SE503627C2 (sv) * 1993-12-27 1996-07-22 Euro Diagnostica Ab Peptid, diagnostiskt antigen och förfarande för hepatit C diagnos
CA2172305A1 (en) * 1995-03-30 1996-10-01 Muneo Aoyama Multiple antigenic peptide comprising at least two hepatitis c virus-associated peptides
US5849800A (en) * 1997-03-28 1998-12-15 The Penn State Research Foundation Use of amantadine for treatment of Hepatitis C
US5977299A (en) * 1997-04-07 1999-11-02 Dade Behring Marburg Gmbh Activated peptides and conjugates
US6030771A (en) * 1997-08-25 2000-02-29 Centers For Disease Control And Prevention Mosaic protein and restriction endonuclease assisted ligation method for making the same
WO2000007023A1 (fr) * 1998-07-30 2000-02-10 Advanced Life Science Institute, Inc. Procede pour la determination de l'hepatite a virus de type c
US7091324B2 (en) 1998-11-05 2006-08-15 Board Of Trustees Of Leland Stanford Junior University Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes
US6210908B1 (en) 1998-11-11 2001-04-03 Dade Behring Marburg Gmbh Activated peptides and conjugates
AT408721B (de) * 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
WO2001058459A1 (en) * 2000-02-14 2001-08-16 Mitsubishi Pharma Corporation Remedies for hepatitis c
ES2248357T3 (es) * 2000-07-07 2006-03-16 Medmira Inc. Composicion de antigeno mosaico de vhc.
WO2002089731A2 (en) * 2001-05-03 2002-11-14 Stanford University Agents for treatment of hcv and methods of use
EP2407470A3 (en) * 2003-10-14 2015-06-10 F. Hoffmann-La Roche Ltd. Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication
CN103159853A (zh) * 2013-02-23 2013-06-19 浙江家和制药有限公司 全人源抗丙型肝炎病毒核心抗原的基因工程Fab抗体及其制备方法和应用
WO2014183109A1 (en) * 2013-05-10 2014-11-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for simultaneous detection of hcv antigen/antibody

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464474A (en) * 1980-07-09 1984-08-07 Connaught Laboratories Limited Non-A, non-B hepatitis assay and vaccine
US5032511A (en) * 1987-03-31 1991-07-16 Mitsubishi Kasei Corporation DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens
JPS6490197A (en) * 1987-09-30 1989-04-06 Mitsubishi Chem Ind Peptide
ES2012739T5 (es) * 1987-11-18 2001-12-01 Chiron Corp Diagnosticos para nanbv.
GB2212511B (en) * 1987-11-18 1992-01-22 Chiron Corp Hepatitis c virus
US5191064A (en) * 1988-09-30 1993-03-02 The Research Foundation For Microbial Diseases (Osaka University) Non-a, non-b hepatitis virus antigen peptide
JPH02167081A (ja) * 1988-12-21 1990-06-27 Tetsuo Nakamura 非Ａ非Ｂ型肝炎ウイルスゲノムＲＮＡ、ｃＤＮＡおよびウイルス抗原蛋白質
WO1990011089A1 (en) * 1989-03-17 1990-10-04 Chiron Corporation Nanbv diagnostics and vaccines
DE69033891T2 (de) * 1989-05-18 2002-08-29 Chiron Corp NANBV-Diagnostika: Polynukleotide, geeignet für Reihenuntersuchungen auf Hepatitis C-Virus
EP0416725A3 (en) * 1989-07-14 1991-03-20 Chugai Seiyaku Kabushiki Kaisha Blood-borne non-a, non-b hepatitis specific protein, dna encoding it, and process for its production
DK0414475T3 (da) * 1989-08-25 1998-02-09 Chiron Corp Fremgangsmåder til dyrkning af HCV i B- eller T-lymfocyt-cellelinier
JP3156200B2 (ja) * 1989-09-15 2001-04-16 国立予防衛生研究所長 新規のｈｃｖ分離株
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
EP0435229A1 (en) * 1989-12-27 1991-07-03 Sanwa Kagaku Kenkyusho Co., Ltd. DNA of non-A, non-B hepatitis virus gene, its clone and use thereof
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
EP0445801A3 (en) * 1990-03-08 1992-07-01 Kuraray Co., Ltd. Peptide and its use
UA41266C2 (uk) * 1990-04-04 2001-09-17 Чірон Корпорейшн Комбінація послідовностей епітопів вірусу гепатиту с (hcv), спосіб виявлення антитіл до вірусу гепатиту с (hcv), набір для виконання аналізу при виявленні антитіл до антигену гепатиту с (hcv)
AU660925B2 (en) * 1990-04-06 1995-07-13 Genelabs Technologies, Inc. Hepatitis C virus epitopes
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
JP3114731B2 (ja) * 1990-08-14 2000-12-04 国立感染症研究所長 Ｃ型肝炎ウイルス抗体検出用ペプチド抗原及びその使用方法
DE59109221D1 (de) * 1990-11-03 2001-11-15 Dade Behring Marburg Gmbh HCV-spezifische Peptide, Mittel dazu und ihre Verwendung

Also Published As

Publication number Publication date
AU1447492A (en) 1992-11-02
ZA922309B (en) 1992-12-30
WO1992017493A2 (en) 1992-10-15
EG20096A (en) 1997-07-31
IE921070A1 (en) 1992-10-07
JPH06506669A (ja) 1994-07-28
CN1051091C (zh) 2000-04-05
CA2107672A1 (en) 1992-10-06
JP3477198B2 (ja) 2003-12-10
US5574132A (en) 1996-11-12
NZ242183A (en) 1994-03-25
CA2107672C (en) 2002-11-26
JP2002128798A (ja) 2002-05-09
EP0507615A1 (en) 1992-10-07
CN1065867A (zh) 1992-11-04
WO1992017493A3 (en) 1992-12-10

Similar Documents

Publication Publication Date Title
IL101425A0 (en) Peptides and mixtures thereof for detecting antibodies to hepatitis c virus,methods for their use and pharmaceutical compositions containing the same
IL105541A0 (en) Monoclonal antibodies to gp130 protein,processes for the preparation thereof and pharmaceutical compositions containing the same
NZ236491A (en) Post-transfusional non-a non-b hepatitis viral polypeptides, dna, antigenic polypeptides and antibodies to the polypeptides
IL90058A0 (en) Hiv envelope peptide,vaccines containing it,monoclonal antibodies directed against said peptide and pharmaceutical compositions containing said antibodies
EE9400455A (et) Peptiidi derivaadid, nende valmistamise protsess, neid sisaldavad ravimpreparaadid ja nende kasutamine
HUT68510A (en) Process for producing hla-restricted hapatitis b virus ctl epitopes and pharmaceutical compositions containing them
IL98393A0 (en) Thiophene derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
HU9401353D0 (en) New lupane derivatives, preparation thereof and pharmaceutical compositions containing them
IL107776A0 (en) Injectable compositions containing taxol and methods for the preparation thereof
IL99393A0 (en) Thiazolidine derivatives,methods for the preparation thereof and pharmaceutical composition containing the same
IL92939A0 (en) Thiazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
DE69126577D1 (de) Antigenes Peptid zum Nachweis von Anti-Hepatitis-C-Virus-Antikörpern und dessen Verwendung
IL98769A (en) Synthetic peptides, mixtures thereof, methods utilizing the same for detecting hiv antibodies and pharmaceutical compositions containing the same
IL95548A0 (en) Thiazole derivatives,processes for the preparation thereof and pharmaceutical composition containing the same
IL93321A0 (en) Acetamide derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA897541B (en) Benzoxazolinone derivatives,process for the preparation thereof and pharmaceutical compositions containing them
IL98770A0 (en) Peptides,analogues and mixtures thereof,methods for detecting antibodies to htlv-i and htlv-ii viruses and pharmaceutical compositions containing the same
EP0586065A3 (en) Antigenic peptides for grouping hepatitis c virus, kit comprising the same and methods for its grouping using the same
IL91675A0 (en) Cyclic compounds,pharmaceutical compositions containing the same and processes for the preparation thereof
AU2370592A (en) Epitopes of the env protein of the hepatitis c virus
IL99543A0 (en) Oligonucleotides,pharmaceutical compositions containing the same and methods for detection of herpes virus utilizing the same
IL96216A0 (en) Peptide derivatives,their preparation and pharmaceutical compositions containing them
AP9300556A0 (en) Peptides,analogues and mixtures thereof for detecting and eliciting antibodies to the e1 and e2 protein of rubella virus
KR950703559A (ko) 신규한 축합 티아졸 유도체, 이의 제조방법 및 이를 함유하는 약제학적 조성물(Novel condensed thiazole derivative, process for producing the same, and pharmaceutical composition containing the same)
AU688259B2 (en) Hepatitis C virus peptides