US5206018A
(en)
*
|
1978-11-03 |
1993-04-27 |
Ayerst, Mckenna & Harrison, Inc. |
Use of rapamycin in treatment of tumors
|
US6548640B1
(en)
*
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
US5221670A
(en)
*
|
1990-09-19 |
1993-06-22 |
American Home Products Corporation |
Rapamycin esters
|
US5378696A
(en)
*
|
1990-09-19 |
1995-01-03 |
American Home Products Corporation |
Rapamycin esters
|
US5321009A
(en)
*
|
1991-04-03 |
1994-06-14 |
American Home Products Corporation |
Method of treating diabetes
|
US5194447A
(en)
*
|
1992-02-18 |
1993-03-16 |
American Home Products Corporation |
Sulfonylcarbamates of rapamycin
|
US5286731A
(en)
*
|
1991-09-17 |
1994-02-15 |
American Home Products Corporation |
Method of treating immunoinflammatory bowel disease
|
US5286730A
(en)
*
|
1991-09-17 |
1994-02-15 |
American Home Products Corporation |
Method of treating immunoinflammatory disease
|
US5164399A
(en)
*
|
1991-11-18 |
1992-11-17 |
American Home Products Corporation |
Rapamycin pyrazoles
|
US5516781A
(en)
*
|
1992-01-09 |
1996-05-14 |
American Home Products Corporation |
Method of treating restenosis with rapamycin
|
CA2086642C
(fr)
*
|
1992-01-09 |
2004-06-15 |
Randall E. Morris |
Methode de traitement des maladies vasculaires hyperproliferatives
|
US5262424A
(en)
*
|
1992-02-18 |
1993-11-16 |
American Home Products Corporation |
Composition of sulfonylcarbamates of rapamycin and method of treating diseases requiring immunosuppression therewith
|
US5177203A
(en)
*
|
1992-03-05 |
1993-01-05 |
American Home Products Corporation |
Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents
|
DK0562853T3
(da)
|
1992-03-27 |
1996-07-01 |
American Home Prod |
29-Demethoxyrapamycin til fremkaldelse af immunsuppression
|
US5288711A
(en)
*
|
1992-04-28 |
1994-02-22 |
American Home Products Corporation |
Method of treating hyperproliferative vascular disease
|
US5256790A
(en)
*
|
1992-08-13 |
1993-10-26 |
American Home Products Corporation |
27-hydroxyrapamycin and derivatives thereof
|
CA2106034A1
(fr)
*
|
1992-09-24 |
1994-03-25 |
Ralph J. Russo |
La 21-norrapamycine
|
US5434260A
(en)
*
|
1992-10-13 |
1995-07-18 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5480988A
(en)
*
|
1992-10-13 |
1996-01-02 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5480989A
(en)
*
|
1992-10-13 |
1996-01-02 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5489680A
(en)
*
|
1992-10-13 |
1996-02-06 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5302584A
(en)
*
|
1992-10-13 |
1994-04-12 |
American Home Products Corporation |
Carbamates of rapamycin
|
US5262423A
(en)
*
|
1992-10-29 |
1993-11-16 |
American Home Products Corporation |
Rapamycin arylcarbonyl and alkoxycarbonyl carbamates as immunosuppressive and antifungal agents
|
US5260300A
(en)
*
|
1992-11-19 |
1993-11-09 |
American Home Products Corporation |
Rapamycin carbonate esters as immuno-suppressant agents
|
US5482945A
(en)
*
|
1992-12-22 |
1996-01-09 |
American Home Products Corporation |
Innovative technique for immunosuppression involving administration of rapamycin loaded formed blood elements
|
US5349060A
(en)
*
|
1993-01-07 |
1994-09-20 |
American Home Products Corporation |
Rapamycin 31-ester with N,N-dimethylglycine derivatives useful as immunosuppressive agents
|
US5252579A
(en)
*
|
1993-02-16 |
1993-10-12 |
American Home Products Corporation |
Macrocyclic immunomodulators
|
US7279561B1
(en)
|
1993-04-23 |
2007-10-09 |
Wyeth |
Anti-rapamycin monoclonal antibodies
|
US5504091A
(en)
*
|
1993-04-23 |
1996-04-02 |
American Home Products Corporation |
Biotin esters of rapamycin
|
WO1994025022A1
(fr)
|
1993-04-23 |
1994-11-10 |
Abbott Laboratories |
Conjugues de rapamycine et anticorps associes
|
US5387680A
(en)
*
|
1993-08-10 |
1995-02-07 |
American Home Products Corporation |
C-22 ring stabilized rapamycin derivatives
|
US5391730A
(en)
*
|
1993-10-08 |
1995-02-21 |
American Home Products Corporation |
Phosphorylcarbamates of rapamycin and oxime derivatives thereof
|
US5373014A
(en)
*
|
1993-10-08 |
1994-12-13 |
American Home Products Corporation |
Rapamycin oximes
|
US5378836A
(en)
*
|
1993-10-08 |
1995-01-03 |
American Home Products Corporation |
Rapamycin oximes and hydrazones
|
US5385909A
(en)
*
|
1993-11-22 |
1995-01-31 |
American Home Products Corporation |
Heterocyclic esters of rapamycin
|
US5385908A
(en)
*
|
1993-11-22 |
1995-01-31 |
American Home Products Corporation |
Hindered esters of rapamycin
|
US5385910A
(en)
*
|
1993-11-22 |
1995-01-31 |
American Home Products Corporation |
Gem-distributed esters of rapamycin
|
US5389639A
(en)
*
|
1993-12-29 |
1995-02-14 |
American Home Products Company |
Amino alkanoic esters of rapamycin
|
US5525610A
(en)
*
|
1994-03-31 |
1996-06-11 |
American Home Products Corporation |
42-Epi-rapamycin and pharmaceutical compositions thereof
|
US5362718A
(en)
|
1994-04-18 |
1994-11-08 |
American Home Products Corporation |
Rapamycin hydroxyesters
|
US5463048A
(en)
*
|
1994-06-14 |
1995-10-31 |
American Home Products Corporation |
Rapamycin amidino carbamates
|
US5491231A
(en)
*
|
1994-11-28 |
1996-02-13 |
American Home Products Corporation |
Hindered N-oxide esters of rapamycin
|
US5563145A
(en)
*
|
1994-12-07 |
1996-10-08 |
American Home Products Corporation |
Rapamycin 42-oximes and hydroxylamines
|
US5561138A
(en)
*
|
1994-12-13 |
1996-10-01 |
American Home Products Corporation |
Method of treating anemia
|
US5496832A
(en)
*
|
1995-03-09 |
1996-03-05 |
American Home Products Corporation |
Method of treating cardiac inflammatory disease
|
FR2736550B1
(fr)
*
|
1995-07-14 |
1998-07-24 |
Sandoz Sa |
Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
|
TW427904B
(en)
*
|
1995-12-07 |
2001-04-01 |
American Home Prod |
Neuroprotective agents
|
US5780462A
(en)
*
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
US5922730A
(en)
*
|
1996-09-09 |
1999-07-13 |
American Home Products Corporation |
Alkylated rapamycin derivatives
|
IT1289815B1
(it)
*
|
1996-12-30 |
1998-10-16 |
Sorin Biomedica Cardio Spa |
Stent per angioplastica e relativo procedimento di produzione
|
US6015809A
(en)
*
|
1998-08-17 |
2000-01-18 |
American Home Products Corporation |
Photocyclized rapamycin
|
US6331547B1
(en)
|
1999-08-18 |
2001-12-18 |
American Home Products Corporation |
Water soluble SDZ RAD esters
|
WO2001068133A1
(fr)
*
|
2000-03-14 |
2001-09-20 |
Genetics Institute, Inc. |
Utilisation de la rapamycine et d'agents inhibiteurs de l'activite b7 en immunomodulation
|
US6670355B2
(en)
|
2000-06-16 |
2003-12-30 |
Wyeth |
Method of treating cardiovascular disease
|
DK1319008T3
(da)
|
2000-09-19 |
2009-02-09 |
Wyeth Corp |
Vandoplöselige rapamycinestere
|
US6399625B1
(en)
|
2000-09-27 |
2002-06-04 |
Wyeth |
1-oxorapamycins
|
US6440991B1
(en)
|
2000-10-02 |
2002-08-27 |
Wyeth |
Ethers of 7-desmethlrapamycin
|
US6399626B1
(en)
|
2000-10-02 |
2002-06-04 |
Wyeth |
Hydroxyesters of 7-desmethylrapamycin
|
TWI286074B
(en)
|
2000-11-15 |
2007-09-01 |
Wyeth Corp |
Pharmaceutical composition containing CCI-779 as an antineoplastic agent
|
TWI296196B
(en)
*
|
2001-04-06 |
2008-05-01 |
Wyeth Corp |
Antineoplastic combinations
|
TWI233359B
(en)
*
|
2001-04-06 |
2005-06-01 |
Wyeth Corp |
Pharmaceutical composition for treating neoplasm
|
US20020198137A1
(en)
*
|
2001-06-01 |
2002-12-26 |
Wyeth |
Antineoplastic combinations
|
UA77200C2
(en)
|
2001-08-07 |
2006-11-15 |
Wyeth Corp |
Antineoplastic combination of cci-779 and bkb-569
|
WO2003018573A1
(fr)
|
2001-08-22 |
2003-03-06 |
Wyeth |
29-enols de la rapamycine
|
US6680330B2
(en)
|
2001-08-22 |
2004-01-20 |
Wyeth |
Rapamycin dialdehydes
|
CN100402031C
(zh)
|
2002-07-30 |
2008-07-16 |
惠氏公司 |
含有瑞帕霉素羟基酯的胃肠外制剂
|
DE60324609D1
(de)
*
|
2002-09-17 |
2008-12-18 |
Wyeth Corp |
GRANULIERTE FORMULIERUNG DES RAPAMYCINESTERS CCl-779
|
AU2003272471B2
(en)
*
|
2002-09-18 |
2010-10-07 |
Trustees Of The University Of Pennsylvania |
Method of inhibiting choroidal neovascularization
|
AU2003301348A1
(en)
*
|
2002-10-18 |
2004-05-04 |
Wyeth |
Compositions and methods for diagnosing and treating autoimmune disease
|
AR042938A1
(es)
*
|
2003-02-06 |
2005-07-06 |
Wyeth Corp |
Uso del cci-779 en el tratamiento de la fibrosis hepatica
|
UA83484C2
(uk)
*
|
2003-03-05 |
2008-07-25 |
Уайт |
Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція
|
KR20060006058A
(ko)
*
|
2003-04-22 |
2006-01-18 |
와이어쓰 |
항신생물성 배합물
|
CN102144961A
(zh)
*
|
2003-09-18 |
2011-08-10 |
参天制药株式会社 |
经巩膜递送
|
AU2005238432A1
(en)
*
|
2004-04-14 |
2005-11-10 |
Wyeth |
Process for preparing rapamycin 42-esters and FK-506 32-esters with dicarboxylic acid, precursors for rapamycin conjugates and antibodies
|
EP1768662A2
(fr)
|
2004-06-24 |
2007-04-04 |
Novartis Vaccines and Diagnostics, Inc. |
Immuno-potentialisateurs a petites molecules et analyses visant a detecter leur presence
|
US8313763B2
(en)
*
|
2004-10-04 |
2012-11-20 |
Tolmar Therapeutics, Inc. |
Sustained delivery formulations of rapamycin compounds
|
KR20070083941A
(ko)
*
|
2004-10-04 |
2007-08-24 |
큐엘티 유에스에이, 인코포레이티드 |
중합체 전달 조성을 갖는 눈 전달
|
BRPI0608152A2
(pt)
*
|
2005-02-09 |
2009-11-10 |
Macusight Inc |
formulações para tratamento ocular
|
US8663639B2
(en)
*
|
2005-02-09 |
2014-03-04 |
Santen Pharmaceutical Co., Ltd. |
Formulations for treating ocular diseases and conditions
|
CA2596392A1
(fr)
*
|
2005-02-15 |
2006-08-24 |
Wyeth |
Formulations orales de cci-779 biodisponibles
|
EP1962839A4
(fr)
|
2005-11-14 |
2010-08-25 |
Ariad Pharma Inc |
Administration d'un inhibiteur de mntor pour le traitement des patients atteints du cancer
|
KR20140093764A
(ko)
|
2006-02-09 |
2014-07-28 |
산텐 세이야꾸 가부시키가이샤 |
안정한 제제와 그 제조 및 사용 방법
|
CN103127100A
(zh)
*
|
2006-03-23 |
2013-06-05 |
参天制药株式会社 |
用于与血管通透性有关的疾病或病症的制剂和方法
|
US20100081681A1
(en)
*
|
2006-08-16 |
2010-04-01 |
Blagosklonny Mikhail V |
Methods and compositions for preventing or treating age-related diseases
|
RU2491934C2
(ru)
*
|
2006-08-22 |
2013-09-10 |
Новартис Аг |
Лечение фиброзирующих нарушений
|
US7867988B2
(en)
|
2006-09-13 |
2011-01-11 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
US20080265343A1
(en)
*
|
2007-04-26 |
2008-10-30 |
International Business Machines Corporation |
Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
|
US20100086579A1
(en)
*
|
2008-10-03 |
2010-04-08 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
US20120064143A1
(en)
|
2008-11-11 |
2012-03-15 |
The Board Of Regents Of The University Of Texas System |
Inhibition of mammalian target of rapamycin
|
CN104997774A
(zh)
|
2009-04-10 |
2015-10-28 |
齐海燕 |
新的抗衰老试剂及其鉴别方法
|
US9283211B1
(en)
|
2009-11-11 |
2016-03-15 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
EP2906214A1
(fr)
|
2012-10-12 |
2015-08-19 |
The Board of Regents of The University of Texas System |
Utilisation d'inhibiteurs mtor pour traiter le déficit cognitif vasculaire
|
WO2014160328A1
(fr)
|
2013-03-13 |
2014-10-02 |
The Board Of Regents Of The University Of Texas System |
Inhibiteurs de mtor pour la prévention de la croissance de polypes intestinaux
|
AU2014373683B2
(en)
|
2013-12-31 |
2020-05-07 |
Rapamycin Holdings, Llc |
Oral rapamycin nanoparticle preparations and use
|
US9700544B2
(en)
|
2013-12-31 |
2017-07-11 |
Neal K Vail |
Oral rapamycin nanoparticle preparations
|