IL100393A0 - 15-nitro-2beta,3beta-dihydro-and 15-nitro-2beta,3beta,6,7-tetrahydrotabersonine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
15-nitro-2beta,3beta-dihydro-and 15-nitro-2beta,3beta,6,7-tetrahydrotabersonine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL100393A0 IL100393A0 IL100393A IL10039391A IL100393A0 IL 100393 A0 IL100393 A0 IL 100393A0 IL 100393 A IL100393 A IL 100393A IL 10039391 A IL10039391 A IL 10039391A IL 100393 A0 IL100393 A0 IL 100393A0
- Authority
- IL
- Israel
- Prior art keywords
- 2beta
- 3beta
- nitro
- tetrahydrotabersonine
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU908313A HU206883B (en) | 1990-12-18 | 1990-12-18 | Process for producing new 15-nitro-2-beta-, 3-beta-dihydro- and 15-nitro-2-beta, 3-beta-, 6,7-tetrahydro-tabersonin derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL100393A0 true IL100393A0 (en) | 1992-09-06 |
Family
ID=10972531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL100393A IL100393A0 (en) | 1990-12-18 | 1991-12-17 | 15-nitro-2beta,3beta-dihydro-and 15-nitro-2beta,3beta,6,7-tetrahydrotabersonine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5204355A (de) |
| EP (1) | EP0491549B1 (de) |
| JP (1) | JPH04334380A (de) |
| KR (1) | KR920012079A (de) |
| CN (1) | CN1063690A (de) |
| AU (1) | AU8972591A (de) |
| CA (1) | CA2057829A1 (de) |
| DE (1) | DE69118340T2 (de) |
| FI (1) | FI915930A (de) |
| HU (1) | HU206883B (de) |
| IE (1) | IE914198A1 (de) |
| IL (1) | IL100393A0 (de) |
| NO (1) | NO914985L (de) |
| PL (1) | PL292813A1 (de) |
| YU (1) | YU195291A (de) |
| ZA (1) | ZA919912B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7205404B1 (en) * | 1999-03-05 | 2007-04-17 | Metabasis Therapeutics, Inc. | Phosphorus-containing prodrugs |
| CN102558178B (zh) * | 2012-01-09 | 2015-06-03 | 中国科学院昆明植物研究所 | 水甘草碱(tabersonine)衍生物及其药物组合物和制备方法与用途 |
| EP3623364A1 (de) | 2014-02-13 | 2020-03-18 | Ligand Pharmaceuticals, Inc. | Organische verbindungen und deren verwendungen |
| CN106687118A (zh) | 2014-07-02 | 2017-05-17 | 配体药物公司 | 前药化合物及其用途 |
| JP2021509907A (ja) | 2018-01-09 | 2021-04-08 | リガンド・ファーマシューティカルズ・インコーポレイテッド | アセタール化合物およびその治療的使用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2358147A1 (fr) * | 1976-07-13 | 1978-02-10 | Parcor | Aspidospermidines |
| JPS62234054A (ja) * | 1985-12-16 | 1987-10-14 | Ono Pharmaceut Co Ltd | ３−フエノキシ（またはフエニルチオ）シクロペンタンカルボニルアミノ酸誘導体およびそれらを有効成分として含有する脳浮腫治療剤 |
-
1990
- 1990-12-18 HU HU908313A patent/HU206883B/hu not_active IP Right Cessation
-
1991
- 1991-12-03 IE IE419891A patent/IE914198A1/en not_active Application Discontinuation
- 1991-12-12 US US07/806,975 patent/US5204355A/en not_active Expired - Fee Related
- 1991-12-17 PL PL29281391A patent/PL292813A1/xx unknown
- 1991-12-17 AU AU89725/91A patent/AU8972591A/en not_active Abandoned
- 1991-12-17 ZA ZA919912A patent/ZA919912B/xx unknown
- 1991-12-17 DE DE69118340T patent/DE69118340T2/de not_active Expired - Fee Related
- 1991-12-17 KR KR1019910023172A patent/KR920012079A/ko not_active Application Discontinuation
- 1991-12-17 FI FI915930A patent/FI915930A/fi not_active Application Discontinuation
- 1991-12-17 NO NO91914985A patent/NO914985L/no unknown
- 1991-12-17 IL IL100393A patent/IL100393A0/xx unknown
- 1991-12-17 EP EP91311694A patent/EP0491549B1/de not_active Expired - Lifetime
- 1991-12-17 CA CA002057829A patent/CA2057829A1/en not_active Abandoned
- 1991-12-18 YU YU195291A patent/YU195291A/sh unknown
- 1991-12-18 CN CN91107991A patent/CN1063690A/zh active Pending
- 1991-12-18 JP JP3334992A patent/JPH04334380A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2057829A1 (en) | 1992-06-19 |
| ZA919912B (en) | 1992-10-28 |
| US5204355A (en) | 1993-04-20 |
| NO914985L (no) | 1992-06-19 |
| FI915930A (fi) | 1992-06-19 |
| FI915930A0 (fi) | 1991-12-17 |
| HU206883B (en) | 1993-01-28 |
| HUT59681A (en) | 1992-06-29 |
| HU908313D0 (en) | 1991-07-29 |
| JPH04334380A (ja) | 1992-11-20 |
| NO914985D0 (no) | 1991-12-17 |
| CN1063690A (zh) | 1992-08-19 |
| EP0491549A1 (de) | 1992-06-24 |
| DE69118340D1 (de) | 1996-05-02 |
| EP0491549B1 (de) | 1996-03-27 |
| YU195291A (sh) | 1994-04-05 |
| PL292813A1 (en) | 1992-12-14 |
| KR920012079A (ko) | 1992-07-25 |
| IE914198A1 (en) | 1992-07-01 |
| AU8972591A (en) | 1992-06-25 |
| DE69118340T2 (de) | 1996-08-29 |
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