IL100328A - Dihydro isoquinoline derivatives their production and pharmaceutical compositions containing them - Google Patents

Dihydro isoquinoline derivatives their production and pharmaceutical compositions containing them

Info

Publication number
IL100328A
IL100328A IL10032891A IL10032891A IL100328A IL 100328 A IL100328 A IL 100328A IL 10032891 A IL10032891 A IL 10032891A IL 10032891 A IL10032891 A IL 10032891A IL 100328 A IL100328 A IL 100328A
Authority
IL
Israel
Prior art keywords
compound
ester
formula
acid addition
addition salt
Prior art date
Application number
IL10032891A
Other languages
English (en)
Other versions
IL100328A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL100328A0 publication Critical patent/IL100328A0/xx
Publication of IL100328A publication Critical patent/IL100328A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
IL10032891A 1990-12-13 1991-12-11 Dihydro isoquinoline derivatives their production and pharmaceutical compositions containing them IL100328A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027055A GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds

Publications (2)

Publication Number Publication Date
IL100328A0 IL100328A0 (en) 1992-09-06
IL100328A true IL100328A (en) 1995-12-08

Family

ID=10686945

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10032891A IL100328A (en) 1990-12-13 1991-12-11 Dihydro isoquinoline derivatives their production and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US5177085A (de)
EP (1) EP0490823B1 (de)
JP (1) JPH0764820B2 (de)
KR (1) KR920012040A (de)
AT (1) ATE145201T1 (de)
AU (1) AU643575B2 (de)
CA (1) CA2057524A1 (de)
CZ (1) CZ281669B6 (de)
DE (1) DE69123124T2 (de)
DK (1) DK0490823T3 (de)
ES (1) ES2093694T3 (de)
FI (1) FI915844A7 (de)
GB (1) GB9027055D0 (de)
GR (1) GR3022034T3 (de)
HU (1) HUT61729A (de)
IE (1) IE914325A1 (de)
IL (1) IL100328A (de)
MX (1) MX9102502A (de)
MY (1) MY129941A (de)
NZ (1) NZ240936A (de)
PL (1) PL168329B1 (de)
PT (1) PT99775B (de)
RU (1) RU2060992C1 (de)
TW (1) TW201736B (de)
ZA (1) ZA919858B (de)

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US5786354A (en) * 1994-06-21 1998-07-28 Celltech Therapeutics, Limited Tri-substituted phenyl derivatives and processes for their preparation
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IT1302677B1 (it) * 1998-10-15 2000-09-29 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
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AU2005212857B2 (en) 2004-02-18 2011-04-28 Takeda Gmbh Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (PDE) 4 inhibitors
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PH25651A (en) * 1986-05-21 1991-08-21 Duphar Int Res New di, tetrahydroisoquinoline derivatives
HU196758B (en) * 1986-05-21 1989-01-30 Gyogyszerkutato Intezet Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them
GB8800397D0 (en) * 1988-01-08 1988-02-10 Sandoz Ltd Improvements in/relating to organic compounds

Also Published As

Publication number Publication date
FI915844A0 (fi) 1991-12-11
HU913760D0 (en) 1992-02-28
FI915844L (fi) 1992-06-14
US5177085A (en) 1993-01-05
EP0490823B1 (de) 1996-11-13
AU643575B2 (en) 1993-11-18
EP0490823A1 (de) 1992-06-17
AU8898591A (en) 1992-06-18
DE69123124D1 (de) 1996-12-19
JPH0764820B2 (ja) 1995-07-12
JPH04275276A (ja) 1992-09-30
DE69123124T2 (de) 1997-05-15
CA2057524A1 (en) 1992-06-14
NZ240936A (en) 1993-09-27
HUT61729A (en) 1993-03-01
CZ281669B6 (cs) 1996-12-11
PT99775A (pt) 1992-11-30
ATE145201T1 (de) 1996-11-15
MX9102502A (es) 1992-06-01
ES2093694T3 (es) 1997-01-01
PT99775B (pt) 1999-05-31
RU2060992C1 (ru) 1996-05-27
MY129941A (en) 2007-05-31
GR3022034T3 (en) 1997-03-31
GB9027055D0 (en) 1991-02-06
KR920012040A (ko) 1992-07-25
CS375791A3 (en) 1992-06-17
IL100328A0 (en) 1992-09-06
ZA919858B (en) 1993-06-14
PL292738A1 (en) 1992-12-14
IE914325A1 (en) 1992-06-17
FI915844A7 (fi) 1992-06-14
DK0490823T3 (de) 1997-02-17
PL168329B1 (pl) 1996-02-29
TW201736B (de) 1993-03-11

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