IL100121A - Recombinant avirulent salmonella that express gamete-specific antigens and antifertility vaccines thereof - Google Patents

Recombinant avirulent salmonella that express gamete-specific antigens and antifertility vaccines thereof

Info

Publication number
IL100121A
IL100121A IL100121A IL10012191A IL100121A IL 100121 A IL100121 A IL 100121A IL 100121 A IL100121 A IL 100121A IL 10012191 A IL10012191 A IL 10012191A IL 100121 A IL100121 A IL 100121A
Authority
IL
Israel
Prior art keywords
microbe
avirulent
gamete
ldh
acrp
Prior art date
Application number
IL100121A
Other languages
English (en)
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of IL100121A publication Critical patent/IL100121A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01011Aspartate-semialdehyde dehydrogenase (1.2.1.11)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL100121A 1990-11-21 1991-11-21 Recombinant avirulent salmonella that express gamete-specific antigens and antifertility vaccines thereof IL100121A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61572090A 1990-11-21 1990-11-21
US79134791A 1991-11-18 1991-11-18

Publications (1)

Publication Number Publication Date
IL100121A true IL100121A (en) 1998-06-15

Family

ID=27087577

Family Applications (1)

Application Number Title Priority Date Filing Date
IL100121A IL100121A (en) 1990-11-21 1991-11-21 Recombinant avirulent salmonella that express gamete-specific antigens and antifertility vaccines thereof

Country Status (9)

Country Link
US (1) US5656488A (es)
EP (1) EP0558631B1 (es)
AT (1) ATE177787T1 (es)
AU (1) AU9094191A (es)
CA (1) CA2096529C (es)
DE (1) DE69131014T2 (es)
ES (1) ES2133311T3 (es)
IL (1) IL100121A (es)
WO (1) WO1992009684A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2095534C (en) * 1990-11-09 2002-09-17 Roy Curtiss, Iii Avirulent microbes and uses therefor
US5480799A (en) * 1993-12-10 1996-01-02 The University Of North Carolina At Chapel Hill Sperm antigen corresponding to a sperm zona binding protein autoantigenic epitope
JPH11507532A (ja) * 1995-06-07 1999-07-06 ワシントン ユニバーシティ 環境に制限される生存能を有する組換え細菌システム
US5922583A (en) * 1995-10-17 1999-07-13 Biostar Inc. Methods for production of recombinant plasmids
EP0977874B1 (en) * 1997-04-18 2005-11-09 Gesellschaft für biotechnologische Forschung mbH (GBF) Attenuated salmonella strain used as a vehicle for oral immunization
DE19720761A1 (de) * 1997-05-07 1998-11-12 Schering Ag Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung
US6024961A (en) * 1997-11-14 2000-02-15 Washington University Recombinant avirulent immunogenic S typhi having rpos positive phenotype
AU1765300A (en) * 1998-12-22 2000-07-12 Dalhousie University Compositions and methods for reducing or preventing fertilization in fish and birds
CA2378472A1 (en) * 1999-07-01 2001-01-11 The University Of Georgia Research Foundation, Inc. Method and composition for affecting reproductive systems
WO2001074383A1 (en) * 2000-04-03 2001-10-11 Uab Research Foundation Chimeric antigen-enterotoxin mucosal immunogens
US6780405B1 (en) * 2000-04-28 2004-08-24 Avant Immunotherapeutics, Inc. Regulated antigen delivery system (RADS)
US6872547B1 (en) 2000-10-11 2005-03-29 Washington University Functional balanced-lethal host-vector systems
AU2002217043A1 (en) * 2000-11-16 2002-05-27 Akzo Nobel N.V. Salmonella vaccine
US20040137003A1 (en) * 2001-04-30 2004-07-15 Curtiss Iii Roy Regulated antigen delivery system (rads)
US20050096283A1 (en) * 2001-12-14 2005-05-05 The Regents Of University Of California Methods of inhibiting fertility
US20050009188A1 (en) * 2002-09-19 2005-01-13 Kitto G. Barrie Animal immunocontraceptives expressed in plants and uses thereof
AU2004204751A1 (en) * 2003-01-09 2004-07-29 The Trustees Of The University Of Pennsylvania Compositions, methods and kits for enhancing the immunogenicity of a bacterial vaccine vector
WO2005093043A1 (en) * 2004-02-27 2005-10-06 Research Development Foundation Dna immunocontraceptive vaccines and uses thereof
US8802419B2 (en) 2006-03-02 2014-08-12 University Of Massachusetts Modified pathogens for use as vaccines
WO2009025888A2 (en) 2007-05-10 2009-02-26 The Arizona Board Of Regents For And On Behalf Of Arizona State University Regulated synthesis of antigen and/or regulated attentuation to enhance vaccine immunogenics and/or safety
WO2008141226A2 (en) * 2007-05-10 2008-11-20 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacteria comprising vectors for expression of nucleic acid sequences encoding antigens
WO2009046449A1 (en) 2007-10-05 2009-04-09 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting an immune response against enteric pathogens
WO2010045620A1 (en) 2008-10-17 2010-04-22 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting an immune response against streptococcus pneumoniae
US9163219B2 (en) 2009-04-14 2015-10-20 Arizona Board Of Regents On Behalf Of Arizona State University Single expression vector for generation of a virus with a segmented genome
WO2010135563A1 (en) 2009-05-22 2010-11-25 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium and methods of antigen and nucleic acid delivery
US9045742B2 (en) 2009-05-29 2015-06-02 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant Edwardsiella bacterium
US9062297B2 (en) 2010-01-13 2015-06-23 The Arizona Board Of Regents For And On Behalf Of Arizona State University Yersinia pestis vaccine
WO2011091291A1 (en) 2010-01-22 2011-07-28 The Arizona Board Of Regents For And On Behalf Of Arizona State University BACTERIUM COMPRISING A REGULATED rfaH NUCLEIC ACID
WO2011150421A2 (en) 2010-05-28 2011-12-01 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium to decrease tumor growth
WO2012003460A2 (en) 2010-07-02 2012-01-05 The Arizona Board Of Regents For And On Behalf Of Arizona State University Compositions and methods for bacterial lysis and neutral lipid production
US9303264B2 (en) 2012-05-18 2016-04-05 The Arizona Board Of Regents For And On Behalf Of Arizona State University Photosynthetic microorganisms expressing thermostable lipase
US9580718B2 (en) 2013-06-17 2017-02-28 Arizona Board Of Regents On Behalf Of Arizona State University Attenuated live bacteria with increased acid resistance and methods of use thereof
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
CN112618706B (zh) * 2020-11-21 2021-09-14 青岛博霖生物科技有限公司 沙门氏菌、鸭疫里默氏杆菌、大肠埃希氏杆菌病三联疫苗

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992520A (en) * 1974-11-27 1976-11-16 Merck & Co., Inc. Anti-fertility vaccine comprising solubilized zona pellucida and anti-serum
US4968619A (en) * 1976-09-27 1990-11-06 Research Corporation Modified microorganisms and method of preparing and using same
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4585651A (en) * 1978-10-17 1986-04-29 Stolle Research & Development Corporation Active/passive immunization of the internal female reproductive organs
US4392997A (en) * 1981-07-06 1983-07-12 Northwestern University Antigenic peptide compounds
US4888170A (en) * 1981-10-22 1989-12-19 Research Corporation Vaccines obtained from antigenic gene products of recombinant genes
US4585587A (en) * 1984-10-19 1986-04-29 Northwestern University Antigenic peptide compounds
US4795634A (en) * 1986-03-14 1989-01-03 Aphton Corporation Method for contraception by immunization against the zona pellucida
AU8192987A (en) * 1986-12-01 1988-06-16 Northwestern University Human ldh-c4 cdna sequences encoding antigenic regions
US4996297A (en) * 1987-10-07 1991-02-26 Zonagen, Inc. Recombinantly expressed rabbit zona pellucida polypeptides
US4990596A (en) * 1989-02-16 1991-02-05 Northwestern University Synthetic peptide producing antibodies of enhanced binding to human LDH-C4
EP0477226A4 (en) * 1989-06-12 1992-09-30 Us Health Contraceptive vaccine based on cloned zona pellucida gene
HUT64394A (en) * 1990-08-27 1993-12-28 Akzo Nv Protein of human zona pellucida zp3

Also Published As

Publication number Publication date
EP0558631A1 (en) 1993-09-08
ATE177787T1 (de) 1999-04-15
DE69131014D1 (de) 1999-04-22
ES2133311T3 (es) 1999-09-16
WO1992009684A1 (en) 1992-06-11
DE69131014T2 (de) 1999-10-07
AU9094191A (en) 1992-06-25
EP0558631B1 (en) 1999-03-17
CA2096529A1 (en) 1992-05-22
US5656488A (en) 1997-08-12
EP0558631A4 (en) 1995-11-22
CA2096529C (en) 2003-01-21

Similar Documents

Publication Publication Date Title
US5656488A (en) Recombinant avirulent salmonella antifertility vaccines
US4888170A (en) Vaccines obtained from antigenic gene products of recombinant genes
JP3428646B2 (ja) ジフテリア毒素ワクチン
EP0465560B1 (en) VACCINES CONTAINING AVIRULENT phoP-TYPE MICROORGANISMS
US6936425B1 (en) Attenuated salmonella SP12 mutants as antigen carriers
Chatfield et al. Construction of a genetically defined Salmonella typhi Ty2 aroA, aroC mutant for the engineering of a candidate oral typhoid-tetanus vaccine
US9050285B2 (en) Recombinant bacterium capable of eliciting an immune response against Streptococcus pneumoniae
CA1338705C (en) Vaccines obtained from antigenic gene products of recombinant genes
US6537558B2 (en) Methods of producing and using virulence attenuated poxR mutant bacteria
US20050260223A1 (en) Salmonella vaccine materials and methods
EP1154797A2 (en) Multi-mutant diphtheria toxin vaccines
EP0584284A1 (en) Recombinant dna-derived cholera toxin subunit analogs
JPH11235191A (ja) 細胞の遺伝的集団において所望の組換え遺伝子を維持する方法
AU2001256957A1 (en) Salmonella vaccine materials and methods
JP3388171B2 (ja) 淋菌piタンパク質およびワクチンの製造
EP0931093B1 (en) Helicobacter pylori live vaccine
WO2003041734A1 (en) Salmonella vaccine
JPH09507028A (ja) イエルシニア ペスチス (Yersinia pestis)感染から防御するための生細菌ベクターを含むワクチン組成物
US20020161192A1 (en) Helicobacter pylori live vaccine
JPH11501203A (ja) 大腸菌およびサルモネラ菌中における淋菌piタンパクおよびワクチンの製造
US20040241190A1 (en) Vaccine preparations
AU2002223922A1 (en) Salmonella vaccine

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed