ES2133311T3 - Vacunas antifertilidad de salmonella avirulenta recombinante. - Google Patents

Vacunas antifertilidad de salmonella avirulenta recombinante.

Info

Publication number
ES2133311T3
ES2133311T3 ES92901072T ES92901072T ES2133311T3 ES 2133311 T3 ES2133311 T3 ES 2133311T3 ES 92901072 T ES92901072 T ES 92901072T ES 92901072 T ES92901072 T ES 92901072T ES 2133311 T3 ES2133311 T3 ES 2133311T3
Authority
ES
Spain
Prior art keywords
avirulent salmonella
recombinant avirulent
antifertility
vaccines
antifertility vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92901072T
Other languages
English (en)
Inventor
Roy Curtiss Iii
Kenneth S K Tung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Washington University in St Louis WUSTL
Original Assignee
University of Washington
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington, Washington University in St Louis WUSTL filed Critical University of Washington
Application granted granted Critical
Publication of ES2133311T3 publication Critical patent/ES2133311T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01011—Aspartate-semialdehyde dehydrogenase (1.2.1.11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE MUESTRAN MICROBIOS NO VIRULENTOS QUE INCLUYEN UN SISTEMA DE EXPRESION RECOMBINANTE QUE CODIFICA UN ANTIGENO ESPECIFICO DE GAMETO. LOS MICROBIOS PUEDEN UTILIZARSE EN COMPOSICIONES PARA INMUNIZAR UN VERTEBRADO CONTRA EL ANTIGENO ESPECIFICO DE GAMETO, PREVINIENDO O REDUCIENDO ASI LA TASA DE FERTILIDAD EN EL VERTEBRADO AL QUE SE ADMINISTRAN.
ES92901072T 1990-11-21 1991-11-20 Vacunas antifertilidad de salmonella avirulenta recombinante. Expired - Lifetime ES2133311T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61572090A 1990-11-21 1990-11-21
US79134791A 1991-11-18 1991-11-18

Publications (1)

Publication Number Publication Date
ES2133311T3 true ES2133311T3 (es) 1999-09-16

Family

ID=27087577

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92901072T Expired - Lifetime ES2133311T3 (es) 1990-11-21 1991-11-20 Vacunas antifertilidad de salmonella avirulenta recombinante.

Country Status (9)

Country Link
US (1) US5656488A (es)
EP (1) EP0558631B1 (es)
AT (1) ATE177787T1 (es)
AU (1) AU9094191A (es)
CA (1) CA2096529C (es)
DE (1) DE69131014T2 (es)
ES (1) ES2133311T3 (es)
IL (1) IL100121A (es)
WO (1) WO1992009684A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE234917T1 (de) * 1990-11-09 2003-04-15 Univ Washington Avirulente salmonella mikroben mit einer mutation in dem cdt gen und ihre verwendung
US5480799A (en) * 1993-12-10 1996-01-02 The University Of North Carolina At Chapel Hill Sperm antigen corresponding to a sperm zona binding protein autoantigenic epitope
DE69635579D1 (de) * 1995-06-07 2006-01-19 Univ St Louis Rekombinant bakterielle system mit umweltbeschränkte lebensfähigkeit
US5922583A (en) * 1995-10-17 1999-07-13 Biostar Inc. Methods for production of recombinant plasmids
ATE309378T1 (de) * 1997-04-18 2005-11-15 Biotechnolog Forschung Gmbh Abgeschwächter salmonellenstamm, gebraucht als vehikel zur oralen immunisierung
DE19720761A1 (de) * 1997-05-07 1998-11-12 Schering Ag Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung
US6024961A (en) 1997-11-14 2000-02-15 Washington University Recombinant avirulent immunogenic S typhi having rpos positive phenotype
CA2356452A1 (en) * 1998-12-22 2000-06-29 Robert Brown Compositions and methods for reducing or preventing fertilization in fish and birds
CA2378472A1 (en) * 1999-07-01 2001-01-11 The University Of Georgia Research Foundation, Inc. Method and composition for affecting reproductive systems
AU2001255217A1 (en) * 2000-04-03 2001-10-15 Uab Research Foundation Chimeric antigen-enterotoxin mucosal immunogens
US6780405B1 (en) * 2000-04-28 2004-08-24 Avant Immunotherapeutics, Inc. Regulated antigen delivery system (RADS)
US6872547B1 (en) 2000-10-11 2005-03-29 Washington University Functional balanced-lethal host-vector systems
EP1345621B1 (en) * 2000-11-16 2008-11-12 Intervet International BV Salmonella vaccine
US20040137003A1 (en) * 2001-04-30 2004-07-15 Curtiss Iii Roy Regulated antigen delivery system (rads)
US20050096283A1 (en) * 2001-12-14 2005-05-05 The Regents Of University Of California Methods of inhibiting fertility
US20050009188A1 (en) * 2002-09-19 2005-01-13 Kitto G. Barrie Animal immunocontraceptives expressed in plants and uses thereof
CA2512812A1 (en) * 2003-01-09 2004-07-29 The Trustees Of The University Of Pennsylvania Compositions, methods and kits for enhancing the immunogenicity of a bacterial vaccine vector
WO2005093043A1 (en) * 2004-02-27 2005-10-06 Research Development Foundation Dna immunocontraceptive vaccines and uses thereof
WO2007106073A2 (en) 2006-03-02 2007-09-20 University Of Massachusetts Modified pathogens for use as vaccines
US20100317084A1 (en) * 2007-05-10 2010-12-16 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacteria comprising vectors for expression of nucleic acid sequences encoding antigens
WO2009025888A2 (en) 2007-05-10 2009-02-26 The Arizona Board Of Regents For And On Behalf Of Arizona State University Regulated synthesis of antigen and/or regulated attentuation to enhance vaccine immunogenics and/or safety
WO2009046451A1 (en) 2007-10-05 2009-04-09 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting a protective immune response against c. perfringens
WO2010045620A1 (en) 2008-10-17 2010-04-22 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting an immune response against streptococcus pneumoniae
US9163219B2 (en) 2009-04-14 2015-10-20 Arizona Board Of Regents On Behalf Of Arizona State University Single expression vector for generation of a virus with a segmented genome
WO2010135563A1 (en) 2009-05-22 2010-11-25 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium and methods of antigen and nucleic acid delivery
US9045742B2 (en) 2009-05-29 2015-06-02 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant Edwardsiella bacterium
US9062297B2 (en) 2010-01-13 2015-06-23 The Arizona Board Of Regents For And On Behalf Of Arizona State University Yersinia pestis vaccine
US8889121B2 (en) 2010-01-22 2014-11-18 The Arizona Board Of Regents For An On Behalf Of Arizona State University Bacterium comprising a regulated rfaH nucleic acid
US9598697B2 (en) 2010-05-28 2017-03-21 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium to decrease tumor growth
US9255283B2 (en) 2010-07-02 2016-02-09 The Arizona Board Of Regents For And On Behalf Of Arizona State University Compositions and methods for bacterial lysis and neutral lipid production
US9303264B2 (en) 2012-05-18 2016-04-05 The Arizona Board Of Regents For And On Behalf Of Arizona State University Photosynthetic microorganisms expressing thermostable lipase
US9580718B2 (en) 2013-06-17 2017-02-28 Arizona Board Of Regents On Behalf Of Arizona State University Attenuated live bacteria with increased acid resistance and methods of use thereof
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
CN112618706B (zh) * 2020-11-21 2021-09-14 青岛博霖生物科技有限公司 沙门氏菌、鸭疫里默氏杆菌、大肠埃希氏杆菌病三联疫苗

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992520A (en) * 1974-11-27 1976-11-16 Merck & Co., Inc. Anti-fertility vaccine comprising solubilized zona pellucida and anti-serum
US4968619A (en) * 1976-09-27 1990-11-06 Research Corporation Modified microorganisms and method of preparing and using same
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4585651A (en) * 1978-10-17 1986-04-29 Stolle Research & Development Corporation Active/passive immunization of the internal female reproductive organs
US4392997A (en) * 1981-07-06 1983-07-12 Northwestern University Antigenic peptide compounds
US4888170A (en) * 1981-10-22 1989-12-19 Research Corporation Vaccines obtained from antigenic gene products of recombinant genes
US4585587A (en) * 1984-10-19 1986-04-29 Northwestern University Antigenic peptide compounds
US4795634A (en) * 1986-03-14 1989-01-03 Aphton Corporation Method for contraception by immunization against the zona pellucida
AU8192987A (en) * 1986-12-01 1988-06-16 Northwestern University Human ldh-c4 cdna sequences encoding antigenic regions
US4996297A (en) * 1987-10-07 1991-02-26 Zonagen, Inc. Recombinantly expressed rabbit zona pellucida polypeptides
US4990596A (en) * 1989-02-16 1991-02-05 Northwestern University Synthetic peptide producing antibodies of enhanced binding to human LDH-C4
JPH05500654A (ja) * 1989-06-12 1993-02-12 アメリカ合衆国 クローン化透明帯遺伝子を基本とする避妊ワクチン
JPH06500690A (ja) * 1990-08-27 1994-01-27 アクゾ・エヌ・ヴエー ヒト卵透明帯タンパク質ｚｐ３

Also Published As

Publication number Publication date
EP0558631A1 (en) 1993-09-08
EP0558631A4 (en) 1995-11-22
EP0558631B1 (en) 1999-03-17
DE69131014D1 (de) 1999-04-22
US5656488A (en) 1997-08-12
ATE177787T1 (de) 1999-04-15
AU9094191A (en) 1992-06-25
CA2096529A1 (en) 1992-05-22
WO1992009684A1 (en) 1992-06-11
DE69131014T2 (de) 1999-10-07
IL100121A (en) 1998-06-15
CA2096529C (en) 2003-01-21

Similar Documents

Publication Publication Date Title
ES2133311T3 (es) Vacunas antifertilidad de salmonella avirulenta recombinante.
ES2145007T3 (es) Determinacion de motivos peptidicos en moleculas del mhc.
MX9204268A (es) Una composicion para la liberacion prolongada y controlada de substancias medicamentosas y un proceso para preparar la misma.
FI953442A (fi) Gonadotropiinia sisältäviä pakastekuivattuja pallosia
PT99340A (pt) Processo para a preparacao de composicoes farmaceuticas anticoncepcionais contendo um estrogenio em mistura com 16-metileno-17 alfa-acetoxi-19-nor-4-pregneno-3,20-diona para administracao por via transdermica e dispositivo para a realizacao da administracao
TR200002930T2 (tr) Kolaylaştırıcı kompozisyonlar
AR033808A1 (es) Una composicion topica de anestesia local y los parches y los envases que la contienen
ES2098029T3 (es) Vacunas de hepatitis que contienen monofosforil lipido a 3-o-desacilado.
AR022008A1 (es) Una composicion de liberacion controlada de galantamina, un proceso para la preparacion de la misma, y el uso de dicha composicion para la preparacion de un medicamento
AU7979094A (en) Methods and compositions for microencapsulation of adjuvants
ES2081102T5 (es) Vacuna para el herpes simple compuesta por glicoproteina gd del hsv y lipido a de monofosforilo 3-desacilado.
ES2172654T3 (es) Uso de nsaid para el tratamiento de carcinomas de celulas escamosas de la cavidad oral u orofaringe.
ES2130575T3 (es) Composiciones inmunogenicas mejoradas contra la gastrina 17 humana.
ES2109241T3 (es) Productos estirados en frio comprendiendo una composicion de resina basada en propileno y procedimiento para su fabricacion.
MX9401225A (es) Composicion de vacuna para prevenir la infeccion con influenza en humanos y metodo para su preparacion.
MX9200324A (es) Nuevos esteroides, procedimiento para su preparacinuevos esteroides, procedimiento para su preparacion y composicion farmaceutica que los contiene. on y composicion farmaceutica que los contiene.
MX9207504A (es) Composiciones curables por humedad y metodo para curar composiciones curables por humedad.
ES2036177T3 (es) Maltitol en polvo directamente compresible y su procedimiento de preparacion.
AR001618A1 (es) Adyuvante de saponina del arbol quillajay y formulacion de vacuna que contiene el mismo
ES2172600T3 (es) Composicion farmaceutica que comprende lamotrigina.
ES2111163T3 (es) Uso de fosfonatos para el tratamiento de la osteoporosis.
ES2187489T3 (es) Composiciones farmaceuticas a base de diclofenac.
FI962550A (fi) Deuterisoidut vaikuttavat aineet transdermaalisessa käyttötarkoituksessa
ES2059130T3 (es) Composiciones farmaceuticas que contienen ipriflavona, procedimiento para su preparacion y uso terapeutico relacionado.
AR248351A1 (es) Una composicion en barra cosmetica transparente.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 558631

Country of ref document: ES