IE922402A1 - Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage - Google Patents

Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage

Info

Publication number
IE922402A1
IE922402A1 IE240292A IE922402A IE922402A1 IE 922402 A1 IE922402 A1 IE 922402A1 IE 240292 A IE240292 A IE 240292A IE 922402 A IE922402 A IE 922402A IE 922402 A1 IE922402 A1 IE 922402A1
Authority
IE
Ireland
Prior art keywords
cntf
protein
recombinant
expression
peripheral nerve
Prior art date
Application number
IE240292A
Other languages
English (en)
Inventor
Franklin D Collins
Deborah Russell
John R Mcdonald
Erwin Freund
Larry J Wilhelm
Duane Mach Bonam
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IE922402A1 publication Critical patent/IE922402A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IE240292A 1991-07-23 1992-07-23 Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage IE922402A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73553891A 1991-07-23 1991-07-23
US75317691A 1991-08-30 1991-08-30

Publications (1)

Publication Number Publication Date
IE922402A1 true IE922402A1 (en) 1993-01-27

Family

ID=27112907

Family Applications (1)

Application Number Title Priority Date Filing Date
IE240292A IE922402A1 (en) 1991-07-23 1992-07-23 Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage

Country Status (12)

Country Link
EP (1) EP0596034A4 (fr)
JP (1) JPH07500725A (fr)
AU (1) AU666327B2 (fr)
CA (1) CA2113815A1 (fr)
FI (1) FI940302A (fr)
HU (1) HUT67352A (fr)
IE (1) IE922402A1 (fr)
IL (1) IL102607A0 (fr)
MX (1) MXPA92004329A (fr)
NO (2) NO940194L (fr)
NZ (1) NZ243691A (fr)
WO (1) WO1993002206A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
IT1288388B1 (it) 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
WO1999064058A1 (fr) * 1998-06-10 1999-12-16 Bml, Inc. Preparations pour la peau et a usage externe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US501914A (en) * 1893-07-25 Method of building engine-foundations
US5011914A (en) * 1989-01-05 1991-04-30 Collins Franklin D Purified ciliary neurotrophic factor
EP0463082A1 (fr) * 1989-03-15 1992-01-02 The Regents Of The University Of California Facteur neurotrope ciliaire purifie
IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
CA2038208A1 (fr) * 1990-03-14 1991-09-15 Francesco Della Valle Procede pour l'isolement et l'expression du facteur neuronotrophique a partir de la zone ciliaire humaine a l'aide d'une technique de l'adn recombinant
JPH07503128A (ja) * 1991-11-11 1995-04-06 フィディーア・ソシエタ・ペル・アチオニ ヒト毛様体ニューロン親和性因子の先端欠失型および突然変異タンパク質型の合成と精製

Also Published As

Publication number Publication date
AU2443292A (en) 1993-02-23
EP0596034A4 (fr) 1995-05-24
FI940302A0 (fi) 1994-01-21
MXPA92004329A (es) 2005-04-01
NZ243691A (en) 1995-12-21
NO940194D0 (no) 1994-01-19
AU666327B2 (en) 1996-02-08
EP0596034A1 (fr) 1994-05-11
IL102607A0 (en) 1993-01-14
FI940302A (fi) 1994-01-21
NO940194L (no) 1994-02-08
JPH07500725A (ja) 1995-01-26
WO1993002206A1 (fr) 1993-02-04
HU9400133D0 (en) 1994-05-30
CA2113815A1 (fr) 1993-02-04
HUT67352A (en) 1995-03-28

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Legal Events

Date Code Title Description
FA9A Application withdrawn section 33(1)