IE921990A1 - Medicaments - Google Patents
MedicamentsInfo
- Publication number
- IE921990A1 IE921990A1 IE199092A IE921990A IE921990A1 IE 921990 A1 IE921990 A1 IE 921990A1 IE 199092 A IE199092 A IE 199092A IE 921990 A IE921990 A IE 921990A IE 921990 A1 IE921990 A1 IE 921990A1
- Authority
- IE
- Ireland
- Prior art keywords
- tetrahydro
- benzazepine
- compound
- hydroxy
- methoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919113379A GB9113379D0 (en) | 1991-06-21 | 1991-06-21 | Medicaments |
GB919113377A GB9113377D0 (en) | 1991-06-21 | 1991-06-21 | Medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
IE921990A1 true IE921990A1 (en) | 1992-12-30 |
Family
ID=26299102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE199092A IE921990A1 (en) | 1991-06-21 | 1992-07-01 | Medicaments |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0589973A1 (fr) |
JP (1) | JPH06508352A (fr) |
KR (1) | KR940701258A (fr) |
AU (1) | AU1927992A (fr) |
CA (1) | CA2110575A1 (fr) |
IE (1) | IE921990A1 (fr) |
MX (1) | MX9203012A (fr) |
PT (1) | PT100602A (fr) |
WO (1) | WO1993000094A2 (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
CA2250186A1 (fr) * | 1996-03-25 | 1997-10-02 | Eli Lilly And Company | Technique de traitement de la douleur due a la migraine |
JPWO2002074746A1 (ja) * | 2001-03-16 | 2004-07-08 | 山之内製薬株式会社 | ベンゾアゼピン誘導体 |
US6953787B2 (en) * | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
RU2423353C1 (ru) | 2002-12-20 | 2011-07-10 | Глэксо Груп Лимитед | Новые производные бензазепина |
PL2332921T3 (pl) | 2003-06-17 | 2016-08-31 | Arena Pharm Inc | Chlorowodorek 8-chloro-1-metylo-2,3,4,5-tetrahydro-1H-3-benzazepiny |
EP2332920A3 (fr) | 2003-06-17 | 2011-12-21 | Arena Pharmaceuticals, Inc. | Procédés de préparation de 3-benzazepines |
TW200510324A (en) * | 2003-08-11 | 2005-03-16 | Lilly Co Eli | 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist |
CN101084193B (zh) | 2004-12-21 | 2011-12-07 | 艾尼纳制药公司 | (r)-8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓盐酸盐的晶型 |
SG158168A1 (en) | 2004-12-23 | 2010-01-29 | Arena Pharm Inc | 5ht2c receptor modulator compositions and methods of use |
JP5199997B2 (ja) | 2006-04-03 | 2013-05-15 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス |
ES2522587T3 (es) | 2006-12-05 | 2014-11-17 | Arena Pharmaceuticals, Inc. | Procesos para preparar (R)-8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzacepina e intermedios de la misma |
US8822727B2 (en) | 2008-03-04 | 2014-09-02 | Arena Pharmaceuticals, Inc. | Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
WO2010148207A2 (fr) | 2009-06-18 | 2010-12-23 | Arena Pharmaceuticals, Inc. | Procédés pour la préparation d'agonistes du récepteur 5-ht2c |
KR20130112848A (ko) | 2010-06-02 | 2013-10-14 | 아레나 파마슈티칼스, 인크. | 5-ht2c 수용체 아고니스트의 제조 방법 |
JP6272695B2 (ja) | 2010-09-01 | 2018-01-31 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 体重管理のために有用な5−ht2cアゴニストの改変放出剤形 |
CA2808900A1 (fr) * | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Formes posologiques a dissolution rapide d'agonistes de 5-ht2c |
WO2012030938A1 (fr) * | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Sels de lorcasérine dotés d'acides optiquement actifs |
EP2611449A1 (fr) | 2010-09-01 | 2013-07-10 | Arena Pharmaceuticals, Inc. | Administration de lorcasérine à des individus présentant une insuffisance rénale |
CN103189360A (zh) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | 5-ht2c激动剂的非吸湿性盐 |
UY34436A (es) | 2012-10-09 | 2014-07-31 | Arena Pharm Inc | Metodo de control del peso |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4659706A (en) * | 1985-12-20 | 1987-04-21 | Smithkline Beckman Corporation | Sulfinyl and sulfonyl substituted 3-benzazepines |
-
1992
- 1992-06-17 PT PT100602A patent/PT100602A/pt not_active Application Discontinuation
- 1992-06-17 KR KR1019930703940A patent/KR940701258A/ko not_active Application Discontinuation
- 1992-06-17 WO PCT/GB1992/001083 patent/WO1993000094A2/fr not_active Application Discontinuation
- 1992-06-17 JP JP4511087A patent/JPH06508352A/ja active Pending
- 1992-06-17 AU AU19279/92A patent/AU1927992A/en not_active Abandoned
- 1992-06-17 CA CA002110575A patent/CA2110575A1/fr not_active Abandoned
- 1992-06-17 EP EP92912293A patent/EP0589973A1/fr not_active Withdrawn
- 1992-06-19 MX MX9203012A patent/MX9203012A/es unknown
- 1992-07-01 IE IE199092A patent/IE921990A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2110575A1 (fr) | 1993-01-07 |
JPH06508352A (ja) | 1994-09-22 |
AU1927992A (en) | 1993-01-25 |
MX9203012A (es) | 1993-07-01 |
WO1993000094A3 (fr) | 1993-03-04 |
EP0589973A1 (fr) | 1994-04-06 |
WO1993000094A2 (fr) | 1993-01-07 |
PT100602A (pt) | 1993-09-30 |
KR940701258A (ko) | 1994-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC9A | Application refused sect. 31(1) |