IE67953B1 - Side Chain Unsaturated 1alpha-Hydroxyvitamin D Homologs - Google Patents

Side Chain Unsaturated 1alpha-Hydroxyvitamin D Homologs

Info

Publication number
IE67953B1
IE67953B1 IE140789A IE140789A IE67953B1 IE 67953 B1 IE67953 B1 IE 67953B1 IE 140789 A IE140789 A IE 140789A IE 140789 A IE140789 A IE 140789A IE 67953 B1 IE67953 B1 IE 67953B1
Authority
IE
Ireland
Prior art keywords
compound
solution
hexane
activity
mmol
Prior art date
Application number
IE140789A
Other languages
English (en)
Other versions
IE891407L (en
Inventor
Hector Deluca
Heinrich K Schnoes
Kato L Perlman
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IE891407L publication Critical patent/IE891407L/xx
Publication of IE67953B1 publication Critical patent/IE67953B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE140789A 1988-04-29 1989-04-28 Side Chain Unsaturated 1alpha-Hydroxyvitamin D Homologs IE67953B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18767588A 1988-04-29 1988-04-29

Publications (2)

Publication Number Publication Date
IE891407L IE891407L (en) 1989-10-29
IE67953B1 true IE67953B1 (en) 1996-05-15

Family

ID=22689977

Family Applications (1)

Application Number Title Priority Date Filing Date
IE140789A IE67953B1 (en) 1988-04-29 1989-04-28 Side Chain Unsaturated 1alpha-Hydroxyvitamin D Homologs

Country Status (13)

Country Link
EP (1) EP0374219A1 (ja)
JP (1) JPH0699454B2 (ja)
KR (1) KR940003360B1 (ja)
AU (1) AU629831B2 (ja)
FR (1) FR2630739A1 (ja)
GB (1) GB2217716A (ja)
HU (1) HU206316B (ja)
IE (1) IE67953B1 (ja)
IL (1) IL90065A (ja)
IN (1) IN169818B (ja)
NL (1) NL8920392A (ja)
RU (1) RU2057117C1 (ja)
WO (1) WO1989010352A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225579A (en) * 1988-03-16 1993-07-06 Hoxan Corporation Method of manufacturing vitamin D2, Vitamin D3, activated type vitamin D2, activated type vitamin D3, and their derivatives
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
JPH0325053A (ja) * 1989-06-23 1991-02-01 Takata Kk プリテンショナー装置
GB8914963D0 (en) * 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
DE4221961A1 (de) * 1992-06-30 1994-01-05 Schering Ag 22-En-25-oxa-Derivate in der Vitamin D-Reihe, Verfahren zu ihrer Herstellung, diese Derivate enthaltenen pharmazeutische Präparate sowie deren Verwendung als Arzneimittel
US5565589A (en) * 1993-11-03 1996-10-15 Wisconsin Alumni Research Foundation 17-formyl-5,6-trans-vitamin D compounds
DK0717034T3 (da) * 1994-12-14 1999-10-18 Duphar Int Res Vitamin D-forbindelser og fremgangsmåde til fremstilling af disse forbindelser
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590488T (de) * 1984-10-04 1986-10-09 Wisconsin Alumni Research Foundation, Madison, Wis. Vitamin D-Derivate und Verfahren zu deren Herstellung
WO1986004333A1 (en) * 1985-01-17 1986-07-31 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
EP0412110B1 (en) * 1988-04-21 1993-07-07 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Novel vitamin d analogues

Also Published As

Publication number Publication date
NL8920392A (nl) 1990-04-02
EP0374219A1 (en) 1990-06-27
HU894747D0 (en) 1990-06-28
WO1989010352A1 (en) 1989-11-02
JPH02504149A (ja) 1990-11-29
IL90065A0 (en) 1989-12-15
GB2217716A (en) 1989-11-01
KR900700448A (ko) 1990-08-13
GB8909573D0 (en) 1989-06-14
IN169818B (ja) 1991-12-28
HUT52476A (en) 1990-07-28
JPH0699454B2 (ja) 1994-12-07
AU629831B2 (en) 1992-10-15
HU206316B (en) 1992-10-28
AU3553389A (en) 1989-11-24
KR940003360B1 (ko) 1994-04-21
FR2630739A1 (fr) 1989-11-03
IE891407L (en) 1989-10-29
RU2057117C1 (ru) 1996-03-27
IL90065A (en) 1996-05-14

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Legal Events

Date Code Title Description
MM4A Patent lapsed