IE63408B1 - Haemostatic wound dressing material - Google Patents
Haemostatic wound dressing materialInfo
- Publication number
- IE63408B1 IE63408B1 IE246689A IE246689A IE63408B1 IE 63408 B1 IE63408 B1 IE 63408B1 IE 246689 A IE246689 A IE 246689A IE 246689 A IE246689 A IE 246689A IE 63408 B1 IE63408 B1 IE 63408B1
- Authority
- IE
- Ireland
- Prior art keywords
- wound dressing
- alginate
- dressing material
- material according
- coating
- Prior art date
Links
- 239000000463 material Substances 0.000 title claims abstract description 49
- 230000000025 haemostatic effect Effects 0.000 title description 9
- 229940030225 antihemorrhagics Drugs 0.000 title description 5
- 235000010443 alginic acid Nutrition 0.000 claims abstract description 55
- 229920000615 alginic acid Polymers 0.000 claims abstract description 55
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims abstract description 50
- 229940072056 alginate Drugs 0.000 claims abstract description 50
- 238000000576 coating method Methods 0.000 claims abstract description 36
- 239000011248 coating agent Substances 0.000 claims abstract description 33
- 239000000758 substrate Substances 0.000 claims abstract description 23
- 229920000728 polyester Polymers 0.000 claims abstract description 9
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000011575 calcium Substances 0.000 claims abstract description 7
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 6
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 6
- 239000011734 sodium Substances 0.000 claims abstract description 5
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims abstract description 3
- 239000011591 potassium Substances 0.000 claims abstract description 3
- 229910052700 potassium Inorganic materials 0.000 claims abstract description 3
- 239000006185 dispersion Substances 0.000 claims abstract 2
- 239000000203 mixture Substances 0.000 claims description 15
- 235000010413 sodium alginate Nutrition 0.000 claims description 8
- 235000010410 calcium alginate Nutrition 0.000 claims description 5
- 239000004014 plasticizer Substances 0.000 claims description 5
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 4
- 229920000742 Cotton Polymers 0.000 claims description 4
- 229910001424 calcium ion Inorganic materials 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- -1 polypropylene Polymers 0.000 claims description 4
- 229910001415 sodium ion Inorganic materials 0.000 claims description 4
- 229920000297 Rayon Polymers 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 239000002964 rayon Substances 0.000 claims description 3
- 239000004743 Polypropylene Substances 0.000 claims description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 2
- 235000010407 ammonium alginate Nutrition 0.000 claims description 2
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- 229920001155 polypropylene Polymers 0.000 claims description 2
- 235000010408 potassium alginate Nutrition 0.000 claims description 2
- 230000000202 analgesic effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000004745 nonwoven fabric Substances 0.000 claims 1
- 238000007763 reverse roll coating Methods 0.000 abstract description 5
- 238000007650 screen-printing Methods 0.000 abstract description 2
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 31
- 208000027418 Wounds and injury Diseases 0.000 description 31
- 239000004744 fabric Substances 0.000 description 17
- 230000035699 permeability Effects 0.000 description 14
- 239000007789 gas Substances 0.000 description 11
- 239000010408 film Substances 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 239000000661 sodium alginate Substances 0.000 description 5
- 229940005550 sodium alginate Drugs 0.000 description 5
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 4
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 229920003169 water-soluble polymer Polymers 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000002745 absorbent Effects 0.000 description 3
- 239000002250 absorbent Substances 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 239000007921 spray Substances 0.000 description 3
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 2
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 description 2
- PHOQVHQSTUBQQK-SQOUGZDYSA-N D-glucono-1,5-lactone Chemical compound OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O PHOQVHQSTUBQQK-SQOUGZDYSA-N 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 229960003168 bronopol Drugs 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 229930182830 galactose Natural products 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 235000012209 glucono delta-lactone Nutrition 0.000 description 2
- 229960003681 gluconolactone Drugs 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- 239000006057 Non-nutritive feed additive Substances 0.000 description 1
- 229920002230 Pectic acid Polymers 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 235000011037 adipic acid Nutrition 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 229940064004 antiseptic throat preparations Drugs 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 238000001266 bandaging Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000000648 calcium alginate Substances 0.000 description 1
- 229960002681 calcium alginate Drugs 0.000 description 1
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 1
- 238000003490 calendering Methods 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 150000002009 diols Chemical class 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003517 fume Substances 0.000 description 1
- 229940051250 hexylene glycol Drugs 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 229940087248 metasol Drugs 0.000 description 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 description 1
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000001000 micrograph Methods 0.000 description 1
- NJTGANWAUPEOAX-UHFFFAOYSA-N molport-023-220-454 Chemical group OCC(O)CO.OCC(O)CO NJTGANWAUPEOAX-UHFFFAOYSA-N 0.000 description 1
- 239000010318 polygalacturonic acid Substances 0.000 description 1
- 229920006264 polyurethane film Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 238000004626 scanning electron microscopy Methods 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Substances C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888818114A GB8818114D0 (en) | 1988-07-29 | 1988-07-29 | Haemostatic wound dressing material |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE892466L IE892466L (en) | 1990-01-29 |
| IE63408B1 true IE63408B1 (en) | 1995-04-19 |
Family
ID=10641332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE246689A IE63408B1 (en) | 1988-07-29 | 1989-07-28 | Haemostatic wound dressing material |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPH039761A (nl) |
| AU (1) | AU634164B2 (nl) |
| CA (1) | CA1340750C (nl) |
| GB (2) | GB8818114D0 (nl) |
| IE (1) | IE63408B1 (nl) |
| NL (1) | NL8901936A (nl) |
| ZA (1) | ZA895796B (nl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9102660D0 (en) * | 1991-02-07 | 1991-03-27 | Ultra Lab Ltd | Wound dressing materials |
| GB2276819B (en) * | 1993-03-23 | 1996-12-11 | Johnson & Johnson Medical | Aqueous wound treatment composition comprising a polysaccharide and hexylene glycol |
| GB9400994D0 (en) * | 1994-01-20 | 1994-03-16 | Bristol Myers Squibb Co | Wound dressing |
| GB9421653D0 (en) † | 1994-10-27 | 1994-12-14 | Innovative Tech Ltd | Wound dressing |
| GB9609474D0 (en) * | 1996-05-08 | 1996-07-10 | Innovative Tech Ltd | Hydrogels |
| GB9813529D0 (en) * | 1998-06-23 | 1998-08-19 | Courtaulds Plc | Nonwoven fabrics and their manufacture and use |
| US20070009586A1 (en) * | 2000-02-29 | 2007-01-11 | Cohen Kelman I | Wound dressings containing complexes of transition metals and alginate for elastase sequestering |
| GB2377177A (en) * | 2001-07-05 | 2003-01-08 | Acordis Speciality Fibres Ltd | Wound dressing comprising gel forming and superabsorbent layers |
| EP1435247B1 (en) * | 2003-01-06 | 2006-11-02 | Speciality Fibres and Materials Limited | Wound dressings comprising an alginate fabric and a superabsorbent |
| WO2006060301A2 (en) | 2004-11-30 | 2006-06-08 | Tissue Technologies, Llc | Starch derivatives and other derivatives, production processes therefor, and wound healing applications therefor |
| FR2907330B1 (fr) * | 2006-10-20 | 2009-11-27 | Gilles Touati | Dispositif de protection des berges d'incision. |
| US8349354B2 (en) * | 2009-09-22 | 2013-01-08 | Ethicon, Inc. | Composite layered hemostasis device |
| RU2014125560A (ru) * | 2011-11-25 | 2015-12-27 | Оцука Фармасьютикал Фэктори, Инк. | Фармацевтическая композиция, пригодная для предотвращения адгезии или гемостаза |
| US10576023B2 (en) | 2015-10-22 | 2020-03-03 | The Procter & Gamble Company | Barrier patch of a foamed film and methods of improving skin appearance |
| WO2017070080A1 (en) | 2015-10-22 | 2017-04-27 | The Procter & Gamble Company | Barrier patch of a foamed film and methods of improving skin appearance |
| US10857076B2 (en) | 2017-01-09 | 2020-12-08 | The Procter & Gamble Company | Barrier patch with soluble film and methods of improving skin appearance |
| US10751265B2 (en) | 2017-01-09 | 2020-08-25 | The Procter & Gamble | Barrier patch with soluble film and methods of improving skin appearance |
| CN110049803B (zh) | 2017-01-09 | 2022-06-07 | 宝洁公司 | 具有可溶性膜的阻隔贴片和改善皮肤外观的方法 |
| EP3641952B1 (en) | 2017-06-22 | 2023-08-02 | The Procter & Gamble Company | Beauty care films including a water-soluble layer and a vapor-deposited coating |
| EP3655050B1 (de) * | 2017-07-21 | 2024-01-17 | Speed Care Mineral GmbH | Neuartige wundauflage zur blutstillung |
| EP3768249B1 (en) | 2018-03-19 | 2024-04-17 | The Procter & Gamble Company | Method of making a barrier patch with soluble film |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB629419A (en) * | 1946-12-05 | 1949-09-20 | Johnson & Johnson Great Britai | Improvements in and relating to surgical dressings |
| GB1329693A (en) * | 1969-09-27 | 1973-09-12 | Wallace Cameron Co Ltd | Haemostatic surgical dressing and a method of manaufacturing same |
| GB1384537A (en) * | 1971-05-20 | 1975-02-19 | Sterling Winthrop Group Ltd | Wound coverings |
| JPS527050B2 (nl) * | 1972-06-22 | 1977-02-26 | ||
| GB1394742A (en) * | 1972-08-03 | 1975-05-21 | Medical Alginates Ltd | Surgical dressing material |
| AT356285B (de) * | 1977-06-30 | 1980-04-25 | Bunzl & Biach Ag | Verbandstoff |
| FR2402474A1 (fr) * | 1977-09-13 | 1979-04-06 | Beghin Say Sa | Procede de fabrication de structures absorbantes et structures obtenues |
| GB1583367A (en) * | 1978-05-19 | 1981-01-28 | Samways B | Wound coverings |
| GB2134792B (en) * | 1983-02-11 | 1986-08-13 | Vernon Carus Ltd | Bioactive composite dressing |
| GB8609367D0 (en) * | 1986-04-17 | 1986-05-21 | Johnson & Johnson | Adhesive wound dressing |
| JPH0649065B2 (ja) * | 1986-05-30 | 1994-06-29 | アルケア株式会社 | 皮膚損傷面保護材 |
-
1988
- 1988-07-29 GB GB888818114A patent/GB8818114D0/en active Pending
-
1989
- 1989-07-26 AU AU38973/89A patent/AU634164B2/en not_active Expired
- 1989-07-26 NL NL8901936A patent/NL8901936A/nl not_active Application Discontinuation
- 1989-07-27 CA CA000606856A patent/CA1340750C/en not_active Expired - Lifetime
- 1989-07-27 GB GB8917154A patent/GB2221620B/en not_active Expired - Lifetime
- 1989-07-28 JP JP1194435A patent/JPH039761A/ja active Pending
- 1989-07-28 ZA ZA895796A patent/ZA895796B/xx unknown
- 1989-07-28 IE IE246689A patent/IE63408B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE892466L (en) | 1990-01-29 |
| CA1340750C (en) | 1999-09-14 |
| GB2221620B (en) | 1991-09-04 |
| GB2221620A (en) | 1990-02-14 |
| AU634164B2 (en) | 1993-02-18 |
| ZA895796B (en) | 1991-03-27 |
| GB8818114D0 (en) | 1988-09-01 |
| NL8901936A (nl) | 1990-02-16 |
| AU3897389A (en) | 1990-02-01 |
| JPH039761A (ja) | 1991-01-17 |
| GB8917154D0 (en) | 1989-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |