IE63385B1 - A method for the selective immunological determination of intact procollagen peptide (Type III) and procollagen (Type III) in body fluids and means for carrying it out - Google Patents

A method for the selective immunological determination of intact procollagen peptide (Type III) and procollagen (Type III) in body fluids and means for carrying it out

Info

Publication number
IE63385B1
IE63385B1 IE128988A IE128988A IE63385B1 IE 63385 B1 IE63385 B1 IE 63385B1 IE 128988 A IE128988 A IE 128988A IE 128988 A IE128988 A IE 128988A IE 63385 B1 IE63385 B1 IE 63385B1
Authority
IE
Ireland
Prior art keywords
type iii
peptide
procollagen
antibodies
bound
Prior art date
Application number
IE128988A
Other languages
English (en)
Other versions
IE881289L (en
Inventor
Dietrich Brocks
Rupert Timpl
Original Assignee
Max Planck Gesellschaft
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft, Hoechst Ag filed Critical Max Planck Gesellschaft
Publication of IE881289L publication Critical patent/IE881289L/en
Publication of IE63385B1 publication Critical patent/IE63385B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Tires In General (AREA)
  • Agricultural Machines (AREA)
  • Lifting Devices For Agricultural Implements (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE128988A 1987-05-02 1988-04-29 A method for the selective immunological determination of intact procollagen peptide (Type III) and procollagen (Type III) in body fluids and means for carrying it out IE63385B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873714634 DE3714634A1 (de) 1987-05-02 1987-05-02 Verfahren zur selektiven immunologischen bestimmung von intaktem prokollagen peptid (typ iii) und prokollagen (typ iii) in koerperfluessigkeiten und mittel zu dessen durchfuehrung

Publications (2)

Publication Number Publication Date
IE881289L IE881289L (en) 1988-11-02
IE63385B1 true IE63385B1 (en) 1995-04-19

Family

ID=6326686

Family Applications (1)

Application Number Title Priority Date Filing Date
IE128988A IE63385B1 (en) 1987-05-02 1988-04-29 A method for the selective immunological determination of intact procollagen peptide (Type III) and procollagen (Type III) in body fluids and means for carrying it out

Country Status (10)

Country Link
EP (1) EP0298210B1 (OSRAM)
JP (1) JPH0780913B2 (OSRAM)
AT (1) ATE98377T1 (OSRAM)
DE (2) DE3714634A1 (OSRAM)
DK (1) DK168872B1 (OSRAM)
ES (1) ES2061545T3 (OSRAM)
FI (1) FI95579C (OSRAM)
IE (1) IE63385B1 (OSRAM)
NO (1) NO175639C (OSRAM)
PT (1) PT87375B (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010862A (en) * 1987-11-06 2000-01-04 Washington Research Foundation Methods of detecting collagen type III degradation in vivo
DE4225038C2 (de) * 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Herstellung und Verwendung von Antikörpern gegen Kollagen
EP0711415B1 (de) * 1993-07-28 1998-07-22 Boehringer Mannheim Gmbh Immunoassay zum nachweis von kollagen typ i oder kollagenfragmenten davon
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
ES2154739T3 (es) 1994-10-17 2001-04-16 Osteometer Biotech As Estimacion del modelo de fragmentacion del colageno en fluidos corporales y el diagnostico de trastornos asociados con el metabolismo del colageno.
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
WO1998026286A2 (en) 1996-12-09 1998-06-18 Osteometer Biotech A/S Sandwich assays for collagen type i fragments
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
ES2216518T3 (es) 1998-05-28 2004-10-16 Bayer Healthcare Ag Anticuerpo monocional y ensayo para detectar el propeptido n-terminal del procolageno iii (piiinp).
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2816841A1 (de) * 1978-04-18 1979-10-31 Max Planck Gesellschaft Radioimmunologische bestimmung von prokollagen (typ iii) und prokollagen- peptid (typ iii)
DE3209149A1 (de) * 1982-03-13 1983-10-06 Hoechst Ag Verfahren zur gemeinsamen immunologischen bestimmung von prokollagen-peptid (typ iii) und prokollagen-peptid col 1 (typ iii) und verfahren zur herstellung von anti-prokollagen-peptid col 1 (typ iii)-serum

Also Published As

Publication number Publication date
DE3886109D1 (de) 1994-01-20
NO881904D0 (no) 1988-04-29
EP0298210A3 (de) 1991-05-15
DE3714634A1 (de) 1988-11-17
ES2061545T3 (es) 1994-12-16
DK168872B1 (da) 1994-06-27
PT87375A (pt) 1989-05-31
FI95579B (fi) 1995-11-15
JPS63292061A (ja) 1988-11-29
PT87375B (pt) 1992-08-31
EP0298210B1 (de) 1993-12-08
NO175639C (no) 1994-11-09
JPH0780913B2 (ja) 1995-08-30
DK232988A (da) 1988-11-03
NO881904L (no) 1988-11-03
ATE98377T1 (de) 1993-12-15
IE881289L (en) 1988-11-02
EP0298210A2 (de) 1989-01-11
NO175639B (OSRAM) 1994-08-01
FI882018A0 (fi) 1988-04-29
FI882018L (fi) 1988-11-03
FI95579C (fi) 1996-02-26
DK232988D0 (da) 1988-04-28

Similar Documents

Publication Publication Date Title
JP2583030B2 (ja) インヒビンに特異な抗体の製造法および抗血清
US4264571A (en) Radioimmunoassay of thymosin α1
IE63385B1 (en) A method for the selective immunological determination of intact procollagen peptide (Type III) and procollagen (Type III) in body fluids and means for carrying it out
US4339427A (en) Radioimmunoassay of thymosinα
Deb et al. Antipeptide antibodies reveal structural and functional characteristics of rat placental lactogen-II
JP2001505999A (ja) Ｔｓｈレセプター自己抗体を検出するためのレセプター結合アッセイ
Zauner et al. Identification of the polypeptide encoded by the URF‐1 gene of Neurospora crassa mtDNA
US5955582A (en) Antibody against a 3-aminophenylboronic-glycated protein complex and its use in an immunoassay
US4543340A (en) Radioimmunoassay of thymosin β4
JP3245052B2 (ja) Ｉ型プロコラーゲンのアミノ末端プロペプチドに対する抗体およびそれを用いるアッセイ法
US5679583A (en) Monoclonal antibodies for the selective immunological determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids
Leung et al. Colonic tumor membrane-associated glycoprotein: Isolation of antigenically-active peptides after chemical cleavage
JPH03163095A (ja) ヒト神経成長因子の部分ペプチド、抗体およびその用途
JPH07110879B2 (ja) モノクロナール抗体
Motte et al. A two-site immunoradiometric assay for serum calcitonin using monoclonal anti-peptide antibodies
Erhard et al. Identification of antigenic differences of recombinant and pituitary bovine growth hormone using monoclonal antibodies
JP2925479B2 (ja) 肺小細胞癌検出薬及びその使用
WO1990011520A1 (en) Antibody against heavy chain of smooth muscle myosin
JP2001122899A (ja) メダカ由来のビテロジェニンおよび抗体
DE60216482T2 (de) Zusammensetzungen und verfahren zum bestimmen von aa4rp
Motté et al. Utilization of synthetic peptides for the study of calcitonin and biosynthetic precursors for calcitonin
Ikeyama et al. Radioimmunoassay of serum thymic factor (FTS)
Mallette General techniques for raising antisera against parathyroid hormone and calcitonin
US6800462B2 (en) Production of recombinant proteins in vivo and use for generating antibodies
US20030158391A1 (en) Anitbodies and method for producing same, the use thereof and immunisation cocktails, immunoassays-sets and peptides

Legal Events

Date Code Title Description
MM4A Patent lapsed