IE58416B1 - Polycyclic aromatic compounds - Google Patents

Polycyclic aromatic compounds

Info

Publication number
IE58416B1
IE58416B1 IE120384A IE120384A IE58416B1 IE 58416 B1 IE58416 B1 IE 58416B1 IE 120384 A IE120384 A IE 120384A IE 120384 A IE120384 A IE 120384A IE 58416 B1 IE58416 B1 IE 58416B1
Authority
IE
Ireland
Prior art keywords
methyl
amino
compound
formula
propanediol
Prior art date
Application number
IE120384A
Other languages
English (en)
Other versions
IE841203L (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IE841203L publication Critical patent/IE841203L/en
Publication of IE58416B1 publication Critical patent/IE58416B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/20—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated the carbon skeleton being saturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/14—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to acyclic carbon atoms
    • C07C205/15—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/62—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems having two or more ring systems containing condensed 1,3-oxazole rings
    • C07D263/64—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems having two or more ring systems containing condensed 1,3-oxazole rings linked in positions 2 and 2' by chains containing six-membered aromatic rings or ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/48—Chrysenes; Hydrogenated chrysenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/50—Pyrenes; Hydrogenated pyrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IE120384A 1983-05-17 1984-05-16 Polycyclic aromatic compounds IE58416B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838313571A GB8313571D0 (en) 1983-05-17 1983-05-17 Chemical compounds
APAP/P/1984/000003A AP1A (en) 1983-05-17 1984-07-16 Polycyclic aromatic compounds

Publications (2)

Publication Number Publication Date
IE841203L IE841203L (en) 1984-11-17
IE58416B1 true IE58416B1 (en) 1993-09-22

Family

ID=39791481

Family Applications (1)

Application Number Title Priority Date Filing Date
IE120384A IE58416B1 (en) 1983-05-17 1984-05-16 Polycyclic aromatic compounds

Country Status (30)

Country Link
US (6) US4530800A (en:Method)
EP (2) EP0125701B1 (en:Method)
JP (3) JPS59225150A (en:Method)
KR (1) KR910000854B1 (en:Method)
AP (1) AP1A (en:Method)
AU (2) AU572509B2 (en:Method)
CA (1) CA1222750A (en:Method)
CS (1) CS273314B2 (en:Method)
CY (1) CY1486A (en:Method)
DD (1) DD223439A5 (en:Method)
DE (2) DE3473141D1 (en:Method)
DK (1) DK242284A (en:Method)
EG (1) EG17595A (en:Method)
ES (3) ES532512A0 (en:Method)
FI (1) FI85263C (en:Method)
GB (2) GB8313571D0 (en:Method)
GR (1) GR82278B (en:Method)
HK (1) HK45089A (en:Method)
HU (1) HU197875B (en:Method)
IE (1) IE58416B1 (en:Method)
IL (1) IL71851A (en:Method)
MC (1) MC1595A1 (en:Method)
NO (1) NO157416C (en:Method)
NZ (1) NZ208168A (en:Method)
PH (1) PH22265A (en:Method)
PL (3) PL145421B1 (en:Method)
PT (1) PT78586A (en:Method)
SG (1) SG22389G (en:Method)
SU (3) SU1535377A3 (en:Method)
ZA (1) ZA843708B (en:Method)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4803221A (en) * 1977-03-15 1989-02-07 Burroughs Wellcome Co. Anthracene derivatives
US4719055A (en) * 1983-05-17 1988-01-12 Burroughs Wellcome Co. Phenanthrene derivatives
US4719046A (en) * 1983-05-17 1988-01-12 Burroughs Wellcome Co. Crysene derivatives
US4829090A (en) * 1983-05-17 1989-05-09 Burroughs Wellcome Co. Chrysene derivatives
US4808625A (en) * 1983-05-17 1989-02-28 Burroughs Wellcome Co. Phenanthrene derivatives
US4803222A (en) * 1983-05-17 1989-02-07 Burroughs Wellcome Co. Fluoranthene derivatives
US4810727A (en) * 1983-05-17 1989-03-07 Burroughs Wellcome Co. Chrysene compound
US4803226A (en) * 1983-05-17 1989-02-07 Burroughs Wellcome Co. Anthracene derivatives
US4808632A (en) * 1983-05-17 1989-02-28 Burroughs Wellcome Co. Fluoranthene derivatives
GB8313571D0 (en) * 1983-05-17 1983-06-22 Wellcome Found Chemical compounds
US4719048A (en) * 1983-05-17 1988-01-12 Burroughs Wellcome Co. Crysene compound
US4717729A (en) * 1983-05-31 1988-01-05 Burroughs Wellcome Co. Triphenylene derivatives
GB8428931D0 (en) * 1984-11-15 1984-12-27 Wellcome Found Polycyclic biocidal compounds
GB8428932D0 (en) * 1984-11-15 1984-12-27 Wellcome Found Polycyclic biocidal compounds
GB8428930D0 (en) * 1984-11-15 1984-12-27 Wellcome Found Polycyclic biocidal compounds
KR900008814B1 (ko) * 1984-11-15 1990-11-30 더 웰컴 파운데이숀 리미티드 살균성 폴리시클릭 화합물의 제조방법
US4808753A (en) * 1985-11-22 1989-02-28 Burroughs Wellcome Co. Carbocyclic derivatives
US4818443A (en) * 1985-11-22 1989-04-04 Burroughs Wellcome Co. Carbocyclic derivatives
US5008286A (en) * 1985-11-22 1991-04-16 Burroughs Wellcome Co. Certain substituted naphthofurans with anti-tumor properties
US4791231A (en) * 1985-11-22 1988-12-13 Burroughs Wellcome Co. Carbocyclic derivatives
US4814502A (en) * 1985-11-22 1989-03-21 Burroughs Wellcome Co. Carbocyclic derivatives
US4810823A (en) * 1985-11-22 1989-03-07 Burroughs Wellcome Co. Carbocyclic derivatives
US4791232A (en) * 1985-11-22 1988-12-13 Burroughs Wellcome Co. Carbocyclic derivatives
US4791233A (en) * 1985-11-22 1988-12-13 Burroughs Wellcome Co. Carbocyclic derivatives
US4827034A (en) * 1985-11-22 1989-05-02 Burroughs Wellcome Co. Carbocyclic derivatives
US4882358A (en) * 1985-11-22 1989-11-21 Burroughs Wellcome Co. Carbocyclic derivatives
US5435667A (en) * 1986-02-20 1995-07-25 Slickbar Products Corp. Protection of piles
JP2735609B2 (ja) * 1989-03-31 1998-04-02 協和醗酵工業株式会社 Ｕｃｎ―１０２８ｄ誘導体
US5416244A (en) * 1991-09-30 1995-05-16 Ohmeda Pharmaceutical Products Division Inc. Preparation of isoflurane
JPH06329679A (ja) * 1993-01-20 1994-11-29 Nissan Chem Ind Ltd 光学活性β−アミノアルコキシボラン錯体
EP1021397A4 (en) * 1997-03-05 2000-10-04 Trimeris Inc BENZANTHRONE COMPOUNDS AND THEIR USE AGAINST VIRUSES
FR2775286B1 (fr) * 1998-02-20 2001-09-07 Centre Nat Rech Scient Derives du triphenylene contre le sida
US6015811A (en) * 1998-10-27 2000-01-18 Board Of Regents, The University Of Texas System Antitumor Chrysene derivatives
DE60012789T2 (de) * 1999-12-30 2005-08-04 Kimberly-Clark Worldwide, Inc., Neenah Eine antivirale lotion-zusammensetzung und mit lotion behandeltes tissueprodukt
US6372785B1 (en) * 2000-05-04 2002-04-16 Keith Chan, President Globoasia, Llc Synthesis of 1,8-dichloro-anthracene analogues and pharmaceutical compositions based thereon
US20050107430A1 (en) * 2003-10-29 2005-05-19 Banik Bimal K. Antimicrobial and antiviral compounds
WO2005089094A2 (en) * 2003-11-21 2005-09-29 The Board Of Regents Of The University And Community College System Of Nevada Materials and methods for the preparation of anisotropically-ordered solids
WO2005119223A1 (en) * 2004-04-14 2005-12-15 Bioprocessors Corp. Compositions of matter useful as ph indicators and related methods
TWI348463B (en) * 2006-03-06 2011-09-11 Lg Chemical Ltd Novel anthracene derivative and organic electronic device using the same
RU2349311C1 (ru) * 2007-08-02 2009-03-20 Михаил Владимирович Кутушов Применение дериватов нафталина в качестве средств для лечения онкологических заболеваний
US20170313920A1 (en) 2010-10-06 2017-11-02 Thomas P. Daly Biological Buffers with Wide Buffering Ranges
US9447310B2 (en) 2008-04-17 2016-09-20 Thomas P. Daly Biological buffers with wide buffering ranges
US8334402B2 (en) * 2008-04-17 2012-12-18 Thomas Daly Biological buffers with wide buffering ranges
US8034951B2 (en) 2008-04-17 2011-10-11 Thomas Daly Biological buffers with wide buffering ranges
US7939659B2 (en) * 2008-04-17 2011-05-10 Thomas Daly Biological buffers with wide buffering ranges
US8822728B2 (en) 2008-04-17 2014-09-02 Thomas Daly Biological buffers with wide buffering ranges
US7635791B2 (en) * 2008-04-17 2009-12-22 Tpat Ip Llc Biological buffers with wide buffering ranges
US9090638B2 (en) 2008-04-17 2015-07-28 Thomas Daly Biological buffers with wide buffering ranges
US8519141B2 (en) 2008-04-17 2013-08-27 Thomas Daly Biological buffers with wide buffering ranges
US9475754B2 (en) 2011-10-06 2016-10-25 Thomas P. Daly Biological buffers with wide buffering ranges
CN103086975A (zh) * 2013-02-05 2013-05-08 广西师范大学 9-羟甲基-10-咪蒽腙及其合成方法和应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2734920A (en) * 1956-02-14 New chemical compounds and their
CH135929A (de) * 1927-02-02 1929-10-15 Ig Farbenindustrie Ag Verfahren zur Herstellung einer Aldehydverbindung.
US2194294A (en) * 1938-07-16 1940-03-19 Du Pont Preparation of n-substituted alkylol amines
US2865925A (en) * 1956-03-23 1958-12-23 Sterling Drug Inc Process for preparing n-(2-hydroxyethyl)-n-(lower-alkyl)-9-aminomethylanthracenes and intermediates therein
US3052722A (en) * 1958-06-24 1962-09-04 May & Baker Ltd Aminophenoxyalkane derivatives
US3198794A (en) * 1960-07-25 1965-08-03 Sterling Drug Inc Pyrenylmethyl quaternary ammonium salts
US3198835A (en) * 1960-07-25 1965-08-03 Sterling Drug Inc Pyrenyl methyl tertiary amino amines
FR95908E (fr) * 1963-11-09 1972-01-31 Degussa Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants.
DE2123992C3 (de) * 1971-05-14 1981-03-19 Richardson-Merrell Inc., New York, N.Y. 3,9-Bis-äther des Fluoranthens und deren Herstellung
US4034040A (en) * 1971-05-24 1977-07-05 Pfizer Inc. Xylene-diamines as antiviral agents
US3882113A (en) * 1972-12-21 1975-05-06 Richardson Merrell Inc Fluoranthene derivatives
US4197149A (en) * 1975-11-05 1980-04-08 Sigri Elektrographit Gmbh Method for joining together shaped bodies of polytetrafluoroethylene
US4062958A (en) * 1976-09-22 1977-12-13 American Cyanamid Company Method of treating anxiety and compositions therefor
US4197249A (en) * 1977-08-15 1980-04-08 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
US4258181A (en) * 1978-09-05 1981-03-24 American Cyanamid Company Substituted 9,10-anthracenebishydrazones
ATE3414T1 (de) * 1979-02-02 1983-06-15 Ciba-Geigy Ag Neues rechts-drehendes, basisches derivat des 9,10-aethano-anthracens, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische praeparate.
US4211726A (en) * 1979-02-16 1980-07-08 American Cyanamid Company Synthesis of substituted 9,10-anthracene-dicarboxaldehydes and 9,10-dihydro-9,10-anthracenedicarboxaldehydes
JPS5999656A (ja) * 1982-11-30 1984-06-08 Toshiba Corp 筒形空気電池
US4532344A (en) * 1983-05-23 1985-07-30 Burroughs Wellcome Co. Fluoranthene derivatives
US4511582A (en) * 1983-06-01 1985-04-16 Burroughs Wellcome Co. Phenanthrene derivatives
GB8313571D0 (en) * 1983-05-17 1983-06-22 Wellcome Found Chemical compounds
US4551282A (en) * 1983-05-31 1985-11-05 Burroughs Wellcome Co. Triphenylene derivatives
US4997249A (en) * 1990-02-26 1991-03-05 The United States Of America As Represented By The Secretary Of The Navy Variable weight fiber optic transversal filter

Also Published As

Publication number Publication date
EG17595A (en) 1990-06-30
GR82278B (en:Method) 1984-12-13
US4720587A (en) 1988-01-19
AP1A (en) 1985-07-03
KR850001896A (ko) 1985-04-10
CS364584A2 (en) 1990-08-14
DD223439A5 (de) 1985-06-12
ES8603376A1 (es) 1985-12-16
NO841954L (no) 1984-11-19
AU599215B2 (en) 1990-07-12
ES8604487A1 (es) 1986-02-01
US4820873A (en) 1989-04-11
JPH034056B2 (en:Method) 1991-01-22
EP0125702B1 (en) 1987-08-12
CA1222750A (en) 1987-06-09
JPH0347157A (ja) 1991-02-28
ZA843708B (en) 1986-01-29
HU197875B (en) 1989-06-28
FI85263B (fi) 1991-12-13
PL145421B1 (en) 1988-09-30
DE3465296D1 (en) 1987-09-17
FI841966A7 (fi) 1984-11-18
MC1595A1 (fr) 1985-05-09
EP0125701A2 (en) 1984-11-21
CS273314B2 (en) 1991-03-12
KR910000854B1 (ko) 1991-02-11
ES532512A0 (es) 1985-12-16
SG22389G (en) 1989-07-14
ES540161A0 (es) 1986-01-01
IL71851A0 (en) 1984-09-30
US4719047A (en) 1988-01-12
PL247759A1 (en) 1985-12-03
ES8603801A1 (es) 1986-01-01
NZ208168A (en) 1988-01-08
PL145420B1 (en) 1988-09-30
AU1305288A (en) 1988-06-16
SU1535377A3 (ru) 1990-01-07
EP0125702A2 (en) 1984-11-21
US4719236A (en) 1988-01-12
DK242284D0 (da) 1984-05-16
PL254244A1 (en) 1986-12-16
DE3473141D1 (en) 1988-09-08
SU1466648A3 (ru) 1989-03-15
AU2809884A (en) 1984-12-06
AU572509B2 (en) 1988-05-12
FI85263C (fi) 1992-03-25
GB8412485D0 (en) 1984-06-20
CY1486A (en) 1989-12-08
EP0125701A3 (en) 1985-03-13
PT78586A (en) 1984-06-01
AP8400003A0 (en) 1984-11-01
EP0125702A3 (en) 1985-03-13
DK242284A (da) 1984-11-18
PL144294B1 (en) 1988-05-31
PL254245A1 (en) 1986-12-16
GB8313571D0 (en) 1983-06-22
HUT34149A (en) 1985-02-28
JPH0684336B2 (ja) 1994-10-26
GB2140416B (en) 1986-08-06
JPS59225150A (ja) 1984-12-18
JPS59225149A (ja) 1984-12-18
FI841966A0 (fi) 1984-05-16
EP0125701B1 (en) 1988-08-03
ES540160A0 (es) 1986-02-01
IE841203L (en) 1984-11-17
NO157416B (no) 1987-12-07
IL71851A (en) 1987-12-31
NO157416C (no) 1988-03-16
US4530800A (en) 1985-07-23
GB2140416A (en) 1984-11-28
US4719049A (en) 1988-01-12
SU1447277A3 (ru) 1988-12-23
PH22265A (en) 1988-07-01
HK45089A (en) 1989-06-09

Similar Documents

Publication Publication Date Title
AP1A (en) Polycyclic aromatic compounds
JPH07228558A (ja) スチルベン誘導体及びそれを含有する制癌剤
US4803221A (en) Anthracene derivatives
HU219238B (en) Cyclic polyamines, process for producing them and pharmaceutical compositions containing the same
US4532344A (en) Fluoranthene derivatives
AU653024B2 (en) Substituted diaminophthalimides and analogues
US4719048A (en) Crysene compound
US4719046A (en) Crysene derivatives
EP0278176B1 (en) Compounds having antitumour and antibacterial properties
US4719055A (en) Phenanthrene derivatives
CN101282946B (zh) 半胱氨酸蛋白酶抑制剂及它们的治疗应用
IE920754A1 (en) 6,9 BIS(SUBSTITUTED-AMINO) BENZO[g]-ISOQUINOLINE-5,10-DIONES
JPS63290868A (ja) ジケトピペラジン誘導体およびその塩類
JPH09506345A (ja) Ｉｌ−１作用の抑制剤としての新規なベンゼンスルホニルイミン誘導体類
WO1992000281A1 (en) 1,2-dihydro-3h-dibenzisoquinoline-1,3-dione anticancer agents
Fioravanti et al. N-Protected. alpha.-amino ketones from enamines and (ethoxycarbonyl) nitrene
US4829090A (en) Chrysene derivatives
KR101876750B1 (ko) 신규한 2-아민 치환 1,4-나프토퀴논 화합물 및 이를 포함하는 암의 예방 또는 치료용 약제학적 조성물
EP0127143B1 (en) Novel aryloxycycloalkanolaminoalkylene aryl ketones
US4927819A (en) Cyclo-octane neuroprotective agents
IE45427B1 (en) Pyrrold 3,2if quinazoline-1,3-diamine and related compounds
Viallon et al. Thermal and acid-catalysed sigmatropic rearrangements of allylamino-methoxy-1, 2-benzoquinones
US4810727A (en) Chrysene compound
Agarwal et al. Angular heterocycles. Utilization of arylaminonaphthoquinones in the synthesis of benzophenothiazines
US4808632A (en) Fluoranthene derivatives