IE47971B1 - Halogen substituted mercaptoacylamino acid - Google Patents
Halogen substituted mercaptoacylamino acidInfo
- Publication number
- IE47971B1 IE47971B1 IE297/79A IE29779A IE47971B1 IE 47971 B1 IE47971 B1 IE 47971B1 IE 297/79 A IE297/79 A IE 297/79A IE 29779 A IE29779 A IE 29779A IE 47971 B1 IE47971 B1 IE 47971B1
- Authority
- IE
- Ireland
- Prior art keywords
- hydrogen
- halogen
- acid
- proline
- compound according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87903278A | 1978-02-21 | 1978-02-21 | |
US93914878A | 1978-09-01 | 1978-09-01 | |
US05/939,147 US4154935A (en) | 1978-02-21 | 1978-09-01 | Halogen substituted mercaptoacylamino acids |
Publications (2)
Publication Number | Publication Date |
---|---|
IE790297L IE790297L (en) | 1979-08-21 |
IE47971B1 true IE47971B1 (en) | 1984-08-08 |
Family
ID=27420501
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE297/79A IE47971B1 (en) | 1978-02-21 | 1979-02-15 | Halogen substituted mercaptoacylamino acid |
Country Status (26)
Country | Link |
---|---|
JP (1) | JPS54125656A (nl) |
AR (2) | AR229152A1 (nl) |
CA (1) | CA1124723A (nl) |
CH (1) | CH639370A5 (nl) |
CS (1) | CS230562B2 (nl) |
DD (1) | DD141827A5 (nl) |
DE (1) | DE2906768A1 (nl) |
DK (1) | DK73379A (nl) |
ES (3) | ES477878A1 (nl) |
FI (1) | FI790593A (nl) |
FR (1) | FR2417499A1 (nl) |
GB (1) | GB2014987B (nl) |
GR (1) | GR82336B (nl) |
HK (1) | HK41383A (nl) |
IE (1) | IE47971B1 (nl) |
IL (1) | IL56662A0 (nl) |
LU (1) | LU80946A1 (nl) |
NL (1) | NL7901319A (nl) |
NO (1) | NO790568L (nl) |
NZ (1) | NZ189626A (nl) |
PH (1) | PH15381A (nl) |
PL (1) | PL118158B1 (nl) |
PT (1) | PT69254A (nl) |
RO (1) | RO77228A (nl) |
SE (1) | SE431643B (nl) |
SU (1) | SU882409A3 (nl) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1144930A (en) * | 1978-08-11 | 1983-04-19 | Miguel A. Ondetti | Mercaptoacyl derivatives of substituted prolines |
NL7809120A (nl) * | 1978-09-07 | 1980-03-11 | Oce Andeno B V Grubbenvorsterw | Werkwijze voor de bereiding van proline-derivaten. |
US4483861A (en) * | 1978-10-31 | 1984-11-20 | Santen Pharmaceutical Co., Ltd. | Antihypertensive sulfur-containing compounds |
CA1132985A (en) * | 1978-12-22 | 1982-10-05 | John Krapcho | Ketal and thioketal derivatives of mercaptoacyl prolines |
ZA802420B (en) * | 1979-05-18 | 1981-04-29 | Squibb & Sons Inc | Aminoacyl derivatives of mercaptoacyl amino acids |
US4288368A (en) * | 1979-07-30 | 1981-09-08 | E. R. Squibb & Sons, Inc. | Dithioacylproline derivatives |
AU542211B2 (en) * | 1980-03-07 | 1985-02-14 | Gruppo Lepetit S.P.A. | Mercaptocycloalkyl carbonyl prolines |
JP2005213165A (ja) * | 2004-01-28 | 2005-08-11 | Mitsui Chemicals Inc | フルオロプロリン類の製造方法 |
JP2011121872A (ja) * | 2009-12-08 | 2011-06-23 | Central Glass Co Ltd | 光学活性N−tert−ブトキシカルボニル−トランス−4−フルオロプロリンの精製方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
-
1970
- 1970-02-15 PH PH22197A patent/PH15381A/en unknown
-
1979
- 1979-02-08 CA CA321,233A patent/CA1124723A/en not_active Expired
- 1979-02-12 NZ NZ189626A patent/NZ189626A/xx unknown
- 1979-02-13 GR GR58343A patent/GR82336B/el unknown
- 1979-02-14 IL IL56662A patent/IL56662A0/xx not_active IP Right Cessation
- 1979-02-15 IE IE297/79A patent/IE47971B1/en not_active IP Right Cessation
- 1979-02-19 GB GB7905788A patent/GB2014987B/en not_active Expired
- 1979-02-20 NO NO790568A patent/NO790568L/no unknown
- 1979-02-20 NL NL7901319A patent/NL7901319A/nl not_active Application Discontinuation
- 1979-02-20 LU LU80946A patent/LU80946A1/xx unknown
- 1979-02-20 ES ES477878A patent/ES477878A1/es not_active Expired
- 1979-02-20 PT PT69254A patent/PT69254A/pt unknown
- 1979-02-20 SE SE7901510A patent/SE431643B/sv not_active IP Right Cessation
- 1979-02-20 CS CS791134A patent/CS230562B2/cs unknown
- 1979-02-20 DK DK73379A patent/DK73379A/da unknown
- 1979-02-20 AR AR275559A patent/AR229152A1/es active
- 1979-02-21 DD DD79211155A patent/DD141827A5/de unknown
- 1979-02-21 DE DE19792906768 patent/DE2906768A1/de not_active Ceased
- 1979-02-21 RO RO7996682A patent/RO77228A/ro unknown
- 1979-02-21 JP JP2019979A patent/JPS54125656A/ja active Granted
- 1979-02-21 FR FR7904455A patent/FR2417499A1/fr active Granted
- 1979-02-21 CH CH168679A patent/CH639370A5/fr not_active IP Right Cessation
- 1979-02-21 FI FI790593A patent/FI790593A/fi unknown
- 1979-02-21 PL PL1979213593A patent/PL118158B1/pl unknown
- 1979-04-23 ES ES479832A patent/ES479832A1/es not_active Expired
- 1979-04-23 ES ES479833A patent/ES479833A1/es not_active Expired
-
1980
- 1980-02-04 SU SU802878653A patent/SU882409A3/ru active
- 1980-06-23 AR AR281499A patent/AR228036A1/es active
-
1983
- 1983-10-13 HK HK413/83A patent/HK41383A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HK41383A (en) | 1983-10-21 |
FR2417499B1 (nl) | 1982-06-04 |
ES477878A1 (es) | 1980-03-01 |
NO790568L (no) | 1979-08-22 |
GB2014987A (en) | 1979-09-05 |
AR229152A1 (es) | 1983-06-30 |
JPH0134986B2 (nl) | 1989-07-21 |
LU80946A1 (fr) | 1979-06-18 |
RO77228A (ro) | 1981-08-17 |
GB2014987B (en) | 1982-11-03 |
CS230562B2 (en) | 1984-08-13 |
IE790297L (en) | 1979-08-21 |
ES479832A1 (es) | 1979-11-16 |
ES479833A1 (es) | 1979-11-16 |
JPS54125656A (en) | 1979-09-29 |
CH639370A5 (fr) | 1983-11-15 |
SE431643B (sv) | 1984-02-20 |
SU882409A3 (ru) | 1981-11-15 |
PT69254A (en) | 1979-03-01 |
PH15381A (en) | 1982-12-17 |
SE7901510L (sv) | 1979-08-22 |
PL118158B1 (en) | 1981-09-30 |
NL7901319A (nl) | 1979-08-23 |
PL213593A1 (nl) | 1980-02-25 |
NZ189626A (en) | 1982-03-09 |
DK73379A (da) | 1979-08-22 |
FR2417499A1 (fr) | 1979-09-14 |
DE2906768A1 (de) | 1979-08-23 |
FI790593A (fi) | 1979-08-22 |
IL56662A0 (en) | 1979-05-31 |
AR228036A1 (es) | 1983-01-14 |
GR82336B (nl) | 1984-12-13 |
CA1124723A (en) | 1982-06-01 |
DD141827A5 (de) | 1980-05-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4154935A (en) | Halogen substituted mercaptoacylamino acids | |
US4086338A (en) | N-carboxyalkanoyl derivatives of azetidine-2-carboxylic acid | |
US4046889A (en) | Azetidine-2-carboxylic acid derivatives | |
US4156084A (en) | Certain dimers of tetrahydropyridine-2-carboxylic acids or pyrroline-2-carboxylic acids and derivatives thereof | |
US4316906A (en) | Mercaptoacyl derivatives of substituted prolines | |
US4296113A (en) | Mercaptoacyl derivatives of keto substituted proline and pipecolic acid | |
HU176021B (en) | Process for producing substituted acylthio-derivatives of proline | |
GB1576161A (en) | Proline derivatives and related compounds | |
FR2491468A1 (fr) | Derives mercapto-acyles de diverses prolines 4-substituees a action anti-hypertensive | |
US4154937A (en) | Hydroxycarbamoylalkylacylpipecolic acid compounds | |
US4154934A (en) | Mercaptoacylamino derivatives of heterocyclic carboxylic acids | |
NZ192449A (en) | Ketal and thioketal derivatives of mercaptoacyl prolines and pharmaceutical compositions | |
US4241076A (en) | Halogenated substituted mercaptoacylamino acids | |
US4296033A (en) | 4-Azido-1-mercaptoacyl proline | |
IE47971B1 (en) | Halogen substituted mercaptoacylamino acid | |
US4186268A (en) | Mercaptoacylpyrrolidine phosphonic acids and related compounds | |
US4206122A (en) | Derivatives of pyrrolidinecarboxaldehyde and piperidinecarboxaldehyde and intermediates therefor | |
US4181663A (en) | Selenium containing derivatives of proline and pipecolic acid | |
US4198515A (en) | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | |
US4198509A (en) | Mercaptoacylpiperazine carboxylic acid compounds | |
US4330548A (en) | Mercaptoacyl derivatives of keto substituted pipecolic acid | |
US4308388A (en) | 4-Azido-1-mercaptoacyl pipecolic acid | |
CA1103255A (en) | Proline derivatives and related compounds | |
CA1138878A (en) | Mercaptoacyl derivatives of keto substituted proline and pipecolic acid | |
KR820001832B1 (ko) | 할로겐 치환 메르캅토아실아미노산류의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |