IE47212B1 - Dihydropyridine derivatives,process for their production and pharmaceutical compositions containing them - Google Patents

Dihydropyridine derivatives,process for their production and pharmaceutical compositions containing them

Info

Publication number
IE47212B1
IE47212B1 IE1231/78A IE123178A IE47212B1 IE 47212 B1 IE47212 B1 IE 47212B1 IE 1231/78 A IE1231/78 A IE 1231/78A IE 123178 A IE123178 A IE 123178A IE 47212 B1 IE47212 B1 IE 47212B1
Authority
IE
Ireland
Prior art keywords
carbon atoms
compound
alkyl
hydrogen
formula
Prior art date
Application number
IE1231/78A
Other languages
English (en)
Other versions
IE781231L (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE781231L publication Critical patent/IE781231L/xx
Publication of IE47212B1 publication Critical patent/IE47212B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IE1231/78A 1977-06-20 1978-06-19 Dihydropyridine derivatives,process for their production and pharmaceutical compositions containing them IE47212B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH752077 1977-06-20
CH286578 1978-03-16

Publications (2)

Publication Number Publication Date
IE781231L IE781231L (en) 1978-12-20
IE47212B1 true IE47212B1 (en) 1984-01-25

Family

ID=25691589

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1231/78A IE47212B1 (en) 1977-06-20 1978-06-19 Dihydropyridine derivatives,process for their production and pharmaceutical compositions containing them

Country Status (20)

Country Link
EP (1) EP0000150B1 (enrdf_load_stackoverflow)
JP (1) JPS54103876A (enrdf_load_stackoverflow)
AT (1) AT376220B (enrdf_load_stackoverflow)
AU (1) AU524000B2 (enrdf_load_stackoverflow)
CA (1) CA1105463A (enrdf_load_stackoverflow)
CY (1) CY1239A (enrdf_load_stackoverflow)
DE (1) DE2860708D1 (enrdf_load_stackoverflow)
DK (1) DK149855C (enrdf_load_stackoverflow)
ES (1) ES470917A1 (enrdf_load_stackoverflow)
FI (1) FI64938C (enrdf_load_stackoverflow)
HK (1) HK65184A (enrdf_load_stackoverflow)
IE (1) IE47212B1 (enrdf_load_stackoverflow)
IL (1) IL54948A (enrdf_load_stackoverflow)
IT (1) IT1105364B (enrdf_load_stackoverflow)
LU (1) LU88342I2 (enrdf_load_stackoverflow)
MY (1) MY8500041A (enrdf_load_stackoverflow)
NL (1) NL930126I2 (enrdf_load_stackoverflow)
NZ (1) NZ187617A (enrdf_load_stackoverflow)
PT (1) PT68191A (enrdf_load_stackoverflow)
SG (1) SG20584G (enrdf_load_stackoverflow)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
DK525179A (da) * 1978-12-18 1980-06-19 Sandoz Ag Fremgangsmaade til fremstilling af benzoxadiazoler og benzothiazoler
BE886259A (fr) * 1979-11-23 1981-05-20 Sandoz Sa Nouveaux medicament a base de derives de la 1,4-dihydropyridine, pour le traitement de l'insuffisance cerebrovasculaire ou a action spamolytique
CH655658B (enrdf_load_stackoverflow) * 1980-09-18 1986-05-15
FI813460L (fi) * 1980-11-10 1982-05-11 Sandoz Ag Nya 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-pyridinderivat deras framstaellningsfoerfarande och dessa innehaollande farmaceutiska kompositioner
DE3269219D1 (en) * 1981-11-17 1986-03-27 Fisons Plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
FR2554109A1 (fr) * 1983-11-01 1985-05-03 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation en therapeutique comme medicaments
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
NL194389C (nl) * 1984-06-14 2002-03-04 Novartis Ag Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager.
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
GB8616047D0 (en) * 1986-07-01 1986-08-06 Sandoz Ltd A 1 4-dihydropyridine derivatives
KR20040088519A (ko) 2002-02-22 2004-10-16 뉴 리버 파마슈티칼스, 인크. 활성 제제 전달 시스템 및 활성 제제의 보호 및 투여 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof

Also Published As

Publication number Publication date
IT7849939A0 (it) 1978-06-19
DK262578A (da) 1978-12-21
FI64938B (fi) 1983-10-31
JPS6360755B2 (enrdf_load_stackoverflow) 1988-11-25
EP0000150B1 (en) 1981-05-20
FI64938C (fi) 1984-02-10
DK149855C (da) 1987-04-21
IT1105364B (it) 1985-10-28
AT376220B (de) 1984-10-25
AU524000B2 (en) 1982-08-26
DE2860708D1 (en) 1981-08-27
IL54948A0 (en) 1978-08-31
IE781231L (en) 1978-12-20
CA1105463A (en) 1981-07-21
NL930126I1 (nl) 1993-11-01
ES470917A1 (es) 1979-10-01
NZ187617A (en) 1980-12-19
MY8500041A (en) 1985-12-31
AU3725278A (en) 1980-01-03
LU88342I2 (fr) 1994-05-04
CY1239A (en) 1984-06-29
PT68191A (fr) 1978-07-01
DK149855B (da) 1986-10-13
ATA443178A (de) 1984-03-15
NL930126I2 (nl) 1995-02-16
SG20584G (en) 1985-03-08
JPS54103876A (en) 1979-08-15
IL54948A (en) 1982-01-31
EP0000150A1 (en) 1979-01-10
HK65184A (en) 1984-08-31
FI781867A7 (fi) 1978-12-21

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