IE44047B1 - Process for the preparation of cyanoacetic acid anilide derivatives - Google Patents

Process for the preparation of cyanoacetic acid anilide derivatives

Info

Publication number
IE44047B1
IE44047B1 IE2706/76A IE270676A IE44047B1 IE 44047 B1 IE44047 B1 IE 44047B1 IE 2706/76 A IE2706/76 A IE 2706/76A IE 270676 A IE270676 A IE 270676A IE 44047 B1 IE44047 B1 IE 44047B1
Authority
IE
Ireland
Prior art keywords
acid
general formula
group
cyanoacetic acid
mixture
Prior art date
Application number
IE2706/76A
Other languages
English (en)
Other versions
IE44047L (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752555685 external-priority patent/DE2555685A1/de
Priority claimed from DE19752557003 external-priority patent/DE2557003A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE44047L publication Critical patent/IE44047L/xx
Publication of IE44047B1 publication Critical patent/IE44047B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IE2706/76A 1975-12-11 1976-12-10 Process for the preparation of cyanoacetic acid anilide derivatives IE44047B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752555685 DE2555685A1 (de) 1975-12-11 1975-12-11 Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
DE19752557003 DE2557003A1 (de) 1975-12-18 1975-12-18 Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel

Publications (2)

Publication Number Publication Date
IE44047L IE44047L (en) 1977-06-11
IE44047B1 true IE44047B1 (en) 1981-07-29

Family

ID=25769723

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2706/76A IE44047B1 (en) 1975-12-11 1976-12-10 Process for the preparation of cyanoacetic acid anilide derivatives

Country Status (12)

Country Link
JP (1) JPS5273830A (de)
CA (1) CA1092133A (de)
CH (6) CH632487A5 (de)
DK (1) DK545976A (de)
ES (6) ES453963A2 (de)
FR (1) FR2334350A2 (de)
GB (1) GB1571990A (de)
IE (1) IE44047B1 (de)
IT (1) IT1124789B (de)
LU (1) LU76354A1 (de)
MX (1) MX4758E (de)
NL (1) NL7613547A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3361451D1 (en) * 1982-03-05 1986-01-23 Fbc Ltd Fungicidal cyanopropenoates and compositions containing them
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
GB8619433D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
US6355678B1 (en) * 1998-06-29 2002-03-12 Parker Hughes Institute Inhibitors of the EGF-receptor tyrosine kinase and methods for their use
CA2724829A1 (en) 2008-07-29 2010-02-04 Alembic Limited A process for the preparation of teriflunomide

Also Published As

Publication number Publication date
NL7613547A (nl) 1977-06-14
CH630341A5 (en) 1982-06-15
CH630342A5 (en) 1982-06-15
GB1571990A (en) 1980-07-23
DK545976A (da) 1977-06-12
ES453963A2 (es) 1978-05-01
LU76354A1 (de) 1977-06-24
FR2334350B2 (de) 1980-03-07
IE44047L (en) 1977-06-11
FR2334350A2 (fr) 1977-07-08
ES475109A1 (es) 1979-04-16
IT1124789B (it) 1986-05-14
ES475108A2 (es) 1979-08-01
CH629757A5 (en) 1982-05-14
ES466542A2 (es) 1979-01-16
CH632487A5 (en) 1982-10-15
ES475110A1 (es) 1979-05-01
CH629756A5 (en) 1982-05-14
CA1092133A (en) 1980-12-23
CH629755A5 (en) 1982-05-14
MX4758E (es) 1982-09-03
ES475111A1 (es) 1979-05-01
JPS5273830A (en) 1977-06-21

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