IE43210L - Adenosine nitrates - Google Patents

Adenosine nitrates

Info

Publication number
IE43210L
IE43210L IE760267A IE26776A IE43210L IE 43210 L IE43210 L IE 43210L IE 760267 A IE760267 A IE 760267A IE 26776 A IE26776 A IE 26776A IE 43210 L IE43210 L IE 43210L
Authority
IE
Ireland
Prior art keywords
amino
nitrates
adenosine
feb
ethyl
Prior art date
Application number
IE760267A
Other versions
IE43210B1 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH203275A external-priority patent/CH606084A5/en
Priority claimed from CH1609475A external-priority patent/CH612948A5/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE43210L publication Critical patent/IE43210L/en
Publication of IE43210B1 publication Critical patent/IE43210B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

1489327 Adenosine nitrates F HOFFMANNLA ROCHE & CO AG 17 Feb 1976 [18 Feb 1975 4 July 1975] 06162/76 Heading C2C Novel compounds I and their acid addition salts in which R<SP>1</SP> and R<SP>2</SP> are H or NO 2 and at least one is NO 2 , and R<SP>5</SP> is OH, C 1-6 alkoxy, amino optionally mono- or di-C 1-6 alkylated, aryl- C 1-6 alkylamino, [2 - (dimethylamino)ethyl]- amino, [2- (2,4 - dinitrophenyl) - ethyl]amino or (2 - nitrooxyethyl)amino, cycloalkylamino or an N-containing heterocyclic ring bonded via an N-atom are prepared by nitrating a compound II Compounds I affect the heart and circulatory dynamics and form with a carrier a pharmaceutical composition which may be administered orally or parenterally. [GB1489327A]
IE267/76A 1975-02-18 1976-02-11 Nitrates of adenosine-5'-carboxylic acid derivatives, process for their manufacture, and pharmaceutical preparations containing them IE43210B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH203275A CH606084A5 (en) 1975-02-18 1975-02-18 (Di) nitrates of adenosine -5'-carboxylic acid derivs
CH874875 1975-07-04
CH1609475A CH612948A5 (en) 1975-12-11 1975-12-11 Process for the preparation of adenosine nitrates

Publications (2)

Publication Number Publication Date
IE43210L true IE43210L (en) 1976-08-18
IE43210B1 IE43210B1 (en) 1981-01-14

Family

ID=27173417

Family Applications (1)

Application Number Title Priority Date Filing Date
IE267/76A IE43210B1 (en) 1975-02-18 1976-02-11 Nitrates of adenosine-5'-carboxylic acid derivatives, process for their manufacture, and pharmaceutical preparations containing them

Country Status (23)

Country Link
JP (1) JPS51105095A (en)
AR (1) AR217398A1 (en)
AU (1) AU497075B2 (en)
BR (1) BR7600997A (en)
CA (1) CA1050534A (en)
DD (1) DD124252A5 (en)
DE (1) DE2606532A1 (en)
DK (1) DK136957B (en)
ES (1) ES445234A1 (en)
FI (1) FI61194C (en)
FR (1) FR2301264A1 (en)
GB (1) GB1489327A (en)
GR (1) GR59304B (en)
HU (1) HU172959B (en)
IE (1) IE43210B1 (en)
IL (1) IL48854A (en)
LU (1) LU74356A1 (en)
NL (1) NL7600663A (en)
NO (1) NO141652C (en)
NZ (1) NZ179785A (en)
PH (1) PH15859A (en)
PT (1) PT64811B (en)
SE (1) SE423237B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310731A (en) * 1984-06-28 1994-05-10 Whitby Research, Inc. N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
EP2876166B1 (en) 2013-11-20 2016-12-14 Roche Diagnostics GmbH New compound for sequencing by synthesis

Also Published As

Publication number Publication date
ES445234A1 (en) 1977-06-01
IE43210B1 (en) 1981-01-14
AR217398A1 (en) 1980-03-31
NO760520L (en) 1976-08-19
FI760184A (en) 1976-08-19
GB1489327A (en) 1977-10-19
NL7600663A (en) 1976-08-20
NZ179785A (en) 1978-04-28
JPS51105095A (en) 1976-09-17
HU172959B (en) 1979-01-28
LU74356A1 (en) 1977-09-12
DK62776A (en) 1976-08-19
FR2301264B1 (en) 1980-06-20
AU497075B2 (en) 1978-11-23
DK136957B (en) 1977-12-19
FI61194B (en) 1982-02-26
FI61194C (en) 1982-06-10
CA1050534A (en) 1979-03-13
DD124252A5 (en) 1977-02-09
IL48854A (en) 1979-12-30
NO141652B (en) 1980-01-07
SE7601725L (en) 1976-08-19
AU1042876A (en) 1977-07-28
GR59304B (en) 1977-12-12
DE2606532A1 (en) 1976-08-26
PH15859A (en) 1983-04-13
SE423237B (en) 1982-04-26
PT64811A (en) 1976-03-01
NO141652C (en) 1980-04-16
IL48854A0 (en) 1976-03-31
FR2301264A1 (en) 1976-09-17
BR7600997A (en) 1976-09-14
DK136957C (en) 1978-05-29
PT64811B (en) 1978-02-06

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