IE39269B1 - Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity - Google Patents
Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivityInfo
- Publication number
- IE39269B1 IE39269B1 IE1039/74A IE103974A IE39269B1 IE 39269 B1 IE39269 B1 IE 39269B1 IE 1039/74 A IE1039/74 A IE 1039/74A IE 103974 A IE103974 A IE 103974A IE 39269 B1 IE39269 B1 IE 39269B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- allergic
- pharmaceutical compositions
- nitrocarbostyrils
- treatment
- Prior art date
Links
- 230000001900 immune effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 title 1
- 208000026935 allergic disease Diseases 0.000 title 1
- 230000000172 allergic effect Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 230000009610 hypersensitivity Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- JWZZKOKVBUJMES-UHFFFAOYSA-N (+-)-Isoprenaline Chemical compound CC(C)NCC(O)C1=CC=C(O)C(O)=C1 JWZZKOKVBUJMES-UHFFFAOYSA-N 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229960001317 isoprenaline Drugs 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- -1 phenoxy, benzyloxy Chemical group 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2400073A GB1453863A (en) | 1973-05-19 | 1973-05-19 | Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity |
| GB2431773 | 1973-05-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39269L IE39269L (en) | 1974-11-19 |
| IE39269B1 true IE39269B1 (en) | 1978-08-30 |
Family
ID=26256830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1039/74A IE39269B1 (en) | 1973-05-19 | 1974-05-15 | Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity |
Country Status (21)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4065457A (en) * | 1973-05-19 | 1977-12-27 | Beecham Group Limited | 4-Hydroxy-3-nitro-carbostyril compounds |
| US4192876A (en) * | 1975-07-23 | 1980-03-11 | Sandoz, Inc. | 4-Hydroxy-3-nitro-quinoline-2(1H)-ones |
| DE2631317A1 (de) * | 1975-07-23 | 1977-02-17 | Sandoz Ag | Organische verbindungen, ihre verwendung und herstellung |
| JPS5919095B2 (ja) * | 1977-06-22 | 1984-05-02 | 大塚製薬株式会社 | キノリン誘導体及びその製造法 |
| JPH0681744B2 (ja) * | 1986-10-06 | 1994-10-19 | 三菱化成株式会社 | ２，４−ジオキシキノリン誘導体の製造方法 |
| US5622965A (en) * | 1993-03-12 | 1997-04-22 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-ones and the use thereof as excitatory amino acid and glycine receptor antagonists |
-
1973
- 1973-05-19 GB GB2400073A patent/GB1453863A/en not_active Expired
-
1974
- 1974-05-15 IE IE1039/74A patent/IE39269B1/xx unknown
- 1974-05-17 CA CA200,335A patent/CA1030539A/en not_active Expired
- 1974-05-17 SE SE7406631A patent/SE7406631L/xx unknown
- 1974-05-17 NL NL7406711A patent/NL7406711A/xx not_active Application Discontinuation
- 1974-05-17 AT AT409674A patent/AT334373B/de not_active IP Right Cessation
- 1974-05-17 DK DK273074AA patent/DK137043B/da unknown
- 1974-05-17 SU SU7402031653A patent/SU578869A3/ru active
- 1974-05-17 FI FI1531/74A patent/FI153174A7/fi unknown
- 1974-05-17 HU HUBE1198A patent/HU168001B/hu unknown
- 1974-05-17 ES ES426427A patent/ES426427A1/es not_active Expired
- 1974-05-17 CH CH683674A patent/CH601243A5/xx not_active IP Right Cessation
- 1974-05-17 IL IL44849A patent/IL44849A/xx unknown
- 1974-05-17 DE DE2424076A patent/DE2424076A1/de active Pending
- 1974-05-17 FR FR7417170A patent/FR2229414B1/fr not_active Expired
- 1974-05-20 JP JP49056448A patent/JPS5030884A/ja active Pending
- 1974-05-20 PH PH15854A patent/PH10621A/en unknown
- 1974-05-20 ZM ZM79/74A patent/ZM7974A1/xx unknown
- 1974-05-20 AR AR253837A patent/AR201506A1/es active
- 1974-05-20 DD DD178631A patent/DD112126A5/xx unknown
- 1974-06-18 IN IN1344/CAL/74A patent/IN139603B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU578869A3 (ru) | 1977-10-30 |
| JPS5030884A (enrdf_load_stackoverflow) | 1975-03-27 |
| ES426427A1 (es) | 1976-09-16 |
| HU168001B (enrdf_load_stackoverflow) | 1976-02-28 |
| DE2424076A1 (de) | 1974-12-05 |
| DK137043C (enrdf_load_stackoverflow) | 1978-06-05 |
| CH601243A5 (enrdf_load_stackoverflow) | 1978-06-30 |
| NL7406711A (enrdf_load_stackoverflow) | 1974-11-21 |
| FR2229414A1 (enrdf_load_stackoverflow) | 1974-12-13 |
| IE39269L (en) | 1974-11-19 |
| AT334373B (de) | 1976-01-10 |
| GB1453863A (en) | 1976-10-27 |
| IL44849A (en) | 1978-04-30 |
| FR2229414B1 (enrdf_load_stackoverflow) | 1977-11-10 |
| FI153174A7 (enrdf_load_stackoverflow) | 1974-11-20 |
| IN139603B (enrdf_load_stackoverflow) | 1976-07-10 |
| DD112126A5 (enrdf_load_stackoverflow) | 1975-03-20 |
| DK137043B (da) | 1978-01-09 |
| PH10621A (en) | 1977-07-19 |
| ZM7974A1 (en) | 1974-12-20 |
| ATA409674A (de) | 1976-05-15 |
| AR201506A1 (es) | 1975-03-21 |
| SE7406631L (enrdf_load_stackoverflow) | 1974-11-20 |
| CA1030539A (en) | 1978-05-02 |
| AU6915874A (en) | 1975-11-20 |
| IL44849A0 (en) | 1974-07-31 |
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