CA1030539A - 4-hydroxy-3-nitrocarbostyril compounds - Google Patents

4-hydroxy-3-nitrocarbostyril compounds

Info

Publication number
CA1030539A
CA1030539A CA200,335A CA200335A CA1030539A CA 1030539 A CA1030539 A CA 1030539A CA 200335 A CA200335 A CA 200335A CA 1030539 A CA1030539 A CA 1030539A
Authority
CA
Canada
Prior art keywords
nitrocarbostyril
hydroxy
compounds
nitrocarbostyril compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA200,335A
Other languages
English (en)
French (fr)
Other versions
CA200335S (en
Inventor
Derek R. Buckle
Harry Smith
Barrie C.C. Cantello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of CA1030539A publication Critical patent/CA1030539A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA200,335A 1973-05-19 1974-05-17 4-hydroxy-3-nitrocarbostyril compounds Expired CA1030539A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2400073A GB1453863A (en) 1973-05-19 1973-05-19 Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity
GB2431773 1973-05-22

Publications (1)

Publication Number Publication Date
CA1030539A true CA1030539A (en) 1978-05-02

Family

ID=26256830

Family Applications (1)

Application Number Title Priority Date Filing Date
CA200,335A Expired CA1030539A (en) 1973-05-19 1974-05-17 4-hydroxy-3-nitrocarbostyril compounds

Country Status (21)

Country Link
JP (1) JPS5030884A (enrdf_load_stackoverflow)
AR (1) AR201506A1 (enrdf_load_stackoverflow)
AT (1) AT334373B (enrdf_load_stackoverflow)
CA (1) CA1030539A (enrdf_load_stackoverflow)
CH (1) CH601243A5 (enrdf_load_stackoverflow)
DD (1) DD112126A5 (enrdf_load_stackoverflow)
DE (1) DE2424076A1 (enrdf_load_stackoverflow)
DK (1) DK137043B (enrdf_load_stackoverflow)
ES (1) ES426427A1 (enrdf_load_stackoverflow)
FI (1) FI153174A7 (enrdf_load_stackoverflow)
FR (1) FR2229414B1 (enrdf_load_stackoverflow)
GB (1) GB1453863A (enrdf_load_stackoverflow)
HU (1) HU168001B (enrdf_load_stackoverflow)
IE (1) IE39269B1 (enrdf_load_stackoverflow)
IL (1) IL44849A (enrdf_load_stackoverflow)
IN (1) IN139603B (enrdf_load_stackoverflow)
NL (1) NL7406711A (enrdf_load_stackoverflow)
PH (1) PH10621A (enrdf_load_stackoverflow)
SE (1) SE7406631L (enrdf_load_stackoverflow)
SU (1) SU578869A3 (enrdf_load_stackoverflow)
ZM (1) ZM7974A1 (enrdf_load_stackoverflow)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065457A (en) * 1973-05-19 1977-12-27 Beecham Group Limited 4-Hydroxy-3-nitro-carbostyril compounds
US4192876A (en) * 1975-07-23 1980-03-11 Sandoz, Inc. 4-Hydroxy-3-nitro-quinoline-2(1H)-ones
DE2631317A1 (de) * 1975-07-23 1977-02-17 Sandoz Ag Organische verbindungen, ihre verwendung und herstellung
JPS5919095B2 (ja) * 1977-06-22 1984-05-02 大塚製薬株式会社 キノリン誘導体及びその製造法
JPH0681744B2 (ja) * 1986-10-06 1994-10-19 三菱化成株式会社 2,4−ジオキシキノリン誘導体の製造方法
US5622965A (en) * 1993-03-12 1997-04-22 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-ones and the use thereof as excitatory amino acid and glycine receptor antagonists

Also Published As

Publication number Publication date
SU578869A3 (ru) 1977-10-30
JPS5030884A (enrdf_load_stackoverflow) 1975-03-27
ES426427A1 (es) 1976-09-16
HU168001B (enrdf_load_stackoverflow) 1976-02-28
DE2424076A1 (de) 1974-12-05
DK137043C (enrdf_load_stackoverflow) 1978-06-05
CH601243A5 (enrdf_load_stackoverflow) 1978-06-30
NL7406711A (enrdf_load_stackoverflow) 1974-11-21
FR2229414A1 (enrdf_load_stackoverflow) 1974-12-13
IE39269L (en) 1974-11-19
AT334373B (de) 1976-01-10
GB1453863A (en) 1976-10-27
IL44849A (en) 1978-04-30
FR2229414B1 (enrdf_load_stackoverflow) 1977-11-10
FI153174A7 (enrdf_load_stackoverflow) 1974-11-20
IN139603B (enrdf_load_stackoverflow) 1976-07-10
DD112126A5 (enrdf_load_stackoverflow) 1975-03-20
DK137043B (da) 1978-01-09
PH10621A (en) 1977-07-19
IE39269B1 (en) 1978-08-30
ZM7974A1 (en) 1974-12-20
ATA409674A (de) 1976-05-15
AR201506A1 (es) 1975-03-21
SE7406631L (enrdf_load_stackoverflow) 1974-11-20
AU6915874A (en) 1975-11-20
IL44849A0 (en) 1974-07-31

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