IE39172B1 - Composition having local anesthetic effect - Google Patents

Composition having local anesthetic effect

Info

Publication number
IE39172B1
IE39172B1 IE522/74A IE52274A IE39172B1 IE 39172 B1 IE39172 B1 IE 39172B1 IE 522/74 A IE522/74 A IE 522/74A IE 52274 A IE52274 A IE 52274A IE 39172 B1 IE39172 B1 IE 39172B1
Authority
IE
Ireland
Prior art keywords
composition
local anesthetic
diisopropylaminoethoxybutyrophenone
volume
anesthetic effect
Prior art date
Application number
IE522/74A
Other versions
IE39172L (en
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of IE39172L publication Critical patent/IE39172L/en
Publication of IE39172B1 publication Critical patent/IE39172B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

o-Diisopropylaminoethoxybutyrophenone is prepared by treating an aqueous solution of an acid addition salt of o-diisopropylaminoethoxybutyrophenone with a base. Preparations of o-diisopropylaminoethoxybutyrophenone in which it is present to at least 1 % by volume, together with 40 to 70 % by volume of isopropanol and up to 40 % by volume of glycerol, produce a deep and long-lasting anaesthesia on topical application to uninjured skin. [GB1464975A]
IE522/74A 1973-03-13 1974-03-12 Composition having local anesthetic effect IE39172B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7303452A SE387536B (en) 1973-03-13 1973-03-13 PROCEDURE FOR PREPARING A LOCAL AESTHETIC PREPARATION

Publications (2)

Publication Number Publication Date
IE39172L IE39172L (en) 1974-09-13
IE39172B1 true IE39172B1 (en) 1978-08-16

Family

ID=20316881

Family Applications (1)

Application Number Title Priority Date Filing Date
IE522/74A IE39172B1 (en) 1973-03-13 1974-03-12 Composition having local anesthetic effect

Country Status (17)

Country Link
JP (1) JPS49124219A (en)
AT (1) AT333965B (en)
BE (1) BE812230A (en)
CA (1) CA1042798A (en)
CH (1) CH608783A5 (en)
DD (1) DD113694A5 (en)
DE (1) DE2410939A1 (en)
DK (1) DK136179B (en)
FI (1) FI53068C (en)
FR (1) FR2221143B1 (en)
GB (1) GB1464975A (en)
HU (1) HU167892B (en)
IE (1) IE39172B1 (en)
NL (1) NL7403079A (en)
SE (1) SE387536B (en)
SU (1) SU556718A3 (en)
ZA (1) ZA741093B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2163956B (en) * 1984-09-08 1988-03-30 Ile De France Percutaneous anaesthetic composition for topical application
US6866844B2 (en) 2002-11-07 2005-03-15 Biomarin Pharmaceutical Inc. Precursor N-acetylgalactosamine-4-sulfatase, methods of treatment using said enzyme and methods for producing and purifying said enzyme
EP1603542A1 (en) 2003-03-14 2005-12-14 Epistem Limited Treatment and/or prevention of non-viral epithelial damage
GB0915315D0 (en) 2009-09-03 2009-10-07 Univ Manchester Use of non-digestible oligosaccharides

Also Published As

Publication number Publication date
ATA172774A (en) 1976-04-15
ZA741093B (en) 1975-01-29
CH608783A5 (en) 1979-01-31
HU167892B (en) 1976-01-28
FI53068C (en) 1978-02-10
NL7403079A (en) 1974-09-17
SE387536B (en) 1976-09-13
CA1042798A (en) 1978-11-21
DK136179B (en) 1977-08-29
DE2410939A1 (en) 1974-09-19
AT333965B (en) 1976-12-27
SU556718A3 (en) 1977-04-30
AU6623674A (en) 1975-09-04
BE812230A (en) 1974-09-13
FI53068B (en) 1977-10-31
FR2221143A1 (en) 1974-10-11
DK136179C (en) 1978-03-13
GB1464975A (en) 1977-02-16
IE39172L (en) 1974-09-13
FR2221143B1 (en) 1977-04-15
DD113694A5 (en) 1975-06-20
JPS49124219A (en) 1974-11-28

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