IE38233B1 - Lysergic acid derivatives - Google Patents
Lysergic acid derivativesInfo
- Publication number
- IE38233B1 IE38233B1 IE1719/72A IE171972A IE38233B1 IE 38233 B1 IE38233 B1 IE 38233B1 IE 1719/72 A IE1719/72 A IE 1719/72A IE 171972 A IE171972 A IE 171972A IE 38233 B1 IE38233 B1 IE 38233B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- carbon atoms
- acid derivatives
- lysergic acid
- dec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Abstract
1410349 Lysergic acid derivatives SANDOZ Ltd 8 Dec 1972 [10 Dec 1971 (2)] 56660/72 Heading C2C Novel compounds (I) (including salts thereof) wherein R 1 is hydrogen or alkyl of 1 to 4 carbon atoms, R 2 is hydrogen or alkyl of 1 to 4 carbon atoms, and R 3 is 3-pyridyl, or 3-pyridyl substituted by alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, hydroxy, halogen of atomic number 9 to 53, amino, or monoalkylamino or dialkylamino, each alkyl substituent having 1 to 4 carbon atoms, are made by reacting corresponding acid derivatives with NHR 2 R 3 or by alkylation to provide (I) where R 1 is alkyl. Pharmaceutical preparations showing salidiurectic and antiserotonin actions contain (I), where R 1 is alkyl, as active ingredient.
[GB1410349A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1805271A CH560716A5 (en) | 1971-12-10 | 1971-12-10 | N-substd lysergic acid amides - s saluretics and serotonin antagonists |
| CH1805171A CH560715A5 (en) | 1971-12-10 | 1971-12-10 | N-substd lysergic acid amides - s saluretics and serotonin antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38233L IE38233L (en) | 1973-06-10 |
| IE38233B1 true IE38233B1 (en) | 1978-02-01 |
Family
ID=25720424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1719/72A IE38233B1 (en) | 1971-12-10 | 1972-12-08 | Lysergic acid derivatives |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS4864099A (en) |
| AT (1) | AT339509B (en) |
| BE (1) | BE792515A (en) |
| DD (1) | DD101672A5 (en) |
| DE (1) | DE2259644A1 (en) |
| ES (1) | ES409461A1 (en) |
| FI (1) | FI53819C (en) |
| FR (1) | FR2162618B1 (en) |
| GB (1) | GB1410349A (en) |
| HU (1) | HU165738B (en) |
| IE (1) | IE38233B1 (en) |
| IL (1) | IL41035A (en) |
| NL (1) | NL7216464A (en) |
| NO (1) | NO135421C (en) |
| PL (1) | PL84879B1 (en) |
| SE (1) | SE398350B (en) |
| SU (1) | SU461500A3 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH653333A5 (en) * | 1981-11-04 | 1985-12-31 | Sandoz Ag | N-SUBSTITUTED ERGOLIN AND 9,10-DIDEHYDROERGOLIN DERIVATIVES, THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THEM. |
| DE91652T1 (en) * | 1982-04-13 | 1984-03-29 | Farmitalia Carlo Erba S.p.A., 20159 Milano | ERGOL DERIVATIVES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| US4563461A (en) * | 1983-03-10 | 1986-01-07 | Eli Lilly And Company | Selective method for blocking 5HT2 receptors |
| EP3941904A1 (en) | 2020-06-12 | 2022-01-26 | Beckley Psytech Limited | Pharmaceutical composition comprising 5-methoxy-n,n-dimethyltryptamine |
| GB202212116D0 (en) | 2022-08-19 | 2022-10-05 | Beckley Psytech Ltd | Pharmaceutically acceptable salts and Compositions thereof |
-
0
- BE BE792515D patent/BE792515A/en unknown
-
1972
- 1972-12-01 SE SE7215662A patent/SE398350B/en unknown
- 1972-12-01 NO NO4414/72A patent/NO135421C/no unknown
- 1972-12-01 FI FI3418/72A patent/FI53819C/en active
- 1972-12-05 NL NL7216464A patent/NL7216464A/xx not_active Application Discontinuation
- 1972-12-06 DE DE2259644A patent/DE2259644A1/en active Pending
- 1972-12-07 AT AT1040772A patent/AT339509B/en not_active IP Right Cessation
- 1972-12-08 GB GB5666072A patent/GB1410349A/en not_active Expired
- 1972-12-08 JP JP47122650A patent/JPS4864099A/ja active Pending
- 1972-12-08 PL PL1972159392A patent/PL84879B1/en unknown
- 1972-12-08 SU SU1855586A patent/SU461500A3/en active
- 1972-12-08 HU HUSA2432A patent/HU165738B/hu unknown
- 1972-12-08 IE IE1719/72A patent/IE38233B1/en unknown
- 1972-12-08 DD DD167453A patent/DD101672A5/xx unknown
- 1972-12-08 FR FR7243832A patent/FR2162618B1/fr not_active Expired
- 1972-12-08 IL IL41035A patent/IL41035A/en unknown
- 1972-12-09 ES ES409461A patent/ES409461A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI53819B (en) | 1978-05-02 |
| DD101672A5 (en) | 1973-11-12 |
| AT339509B (en) | 1977-10-25 |
| DE2259644A1 (en) | 1973-06-14 |
| NO135421C (en) | 1977-04-05 |
| IL41035A (en) | 1975-08-31 |
| NO135421B (en) | 1976-12-27 |
| JPS4864099A (en) | 1973-09-05 |
| IE38233L (en) | 1973-06-10 |
| BE792515A (en) | 1973-06-08 |
| IL41035A0 (en) | 1973-02-28 |
| SU461500A3 (en) | 1975-02-25 |
| FR2162618A1 (en) | 1973-07-20 |
| PL84879B1 (en) | 1976-04-30 |
| GB1410349A (en) | 1975-10-15 |
| FI53819C (en) | 1978-08-10 |
| NL7216464A (en) | 1973-06-13 |
| ES409461A1 (en) | 1976-04-01 |
| FR2162618B1 (en) | 1975-10-17 |
| ATA1040772A (en) | 1977-02-15 |
| HU165738B (en) | 1974-10-28 |
| SE398350B (en) | 1977-12-19 |
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