ES409461A1 - Lysergic acid derivatives - Google Patents

Lysergic acid derivatives

Info

Publication number
ES409461A1
ES409461A1 ES409461A ES409461A ES409461A1 ES 409461 A1 ES409461 A1 ES 409461A1 ES 409461 A ES409461 A ES 409461A ES 409461 A ES409461 A ES 409461A ES 409461 A1 ES409461 A1 ES 409461A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
formula
hydrogen
indicated above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES409461A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1805171A external-priority patent/CH560715A5/en
Priority claimed from CH1805271A external-priority patent/CH560716A5/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES409461A1 publication Critical patent/ES409461A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Process for obtaining lysergic acid amide derivatives, of formula I, ** (See formula) ** wherein R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen or alkyl of 1 to 4 carbon atoms, and R3 is 3-pyridyl, or 3-pyridyl substituted by alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, hydroxy, halogen with atomic number of 9 to 53, amino, or monoalkylamino or dialkylamino, each alkyl substituent containing 1 to 4 carbon atoms, characterized in that a) a reactive functional derivative is reacted of an acid of formula II, ** (See formula) ** wherein R1 has the meaning indicated above, in an inert organic solvent, in the presence of an acid binding agent, with a compound of formula III, wherein R2 and R3 have the meanings indicated above. (Machine-translation by Google Translate, not legally binding)
ES409461A 1971-12-10 1972-12-09 Lysergic acid derivatives Expired ES409461A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1805171A CH560715A5 (en) 1971-12-10 1971-12-10 N-substd lysergic acid amides - s saluretics and serotonin antagonists
CH1805271A CH560716A5 (en) 1971-12-10 1971-12-10 N-substd lysergic acid amides - s saluretics and serotonin antagonists

Publications (1)

Publication Number Publication Date
ES409461A1 true ES409461A1 (en) 1976-04-01

Family

ID=25720424

Family Applications (1)

Application Number Title Priority Date Filing Date
ES409461A Expired ES409461A1 (en) 1971-12-10 1972-12-09 Lysergic acid derivatives

Country Status (17)

Country Link
JP (1) JPS4864099A (en)
AT (1) AT339509B (en)
BE (1) BE792515A (en)
DD (1) DD101672A5 (en)
DE (1) DE2259644A1 (en)
ES (1) ES409461A1 (en)
FI (1) FI53819C (en)
FR (1) FR2162618B1 (en)
GB (1) GB1410349A (en)
HU (1) HU165738B (en)
IE (1) IE38233B1 (en)
IL (1) IL41035A (en)
NL (1) NL7216464A (en)
NO (1) NO135421C (en)
PL (1) PL84879B1 (en)
SE (1) SE398350B (en)
SU (1) SU461500A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653333A5 (en) * 1981-11-04 1985-12-31 Sandoz Ag N-SUBSTITUTED ERGOLIN AND 9,10-DIDEHYDROERGOLIN DERIVATIVES, THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THEM.
DE3362248D1 (en) * 1982-04-13 1986-04-03 Erba Farmitalia Ergoline derivatives, process for producing the ergoline derivatives and pharmaceutical compositions containing them
US4563461A (en) * 1983-03-10 1986-01-07 Eli Lilly And Company Selective method for blocking 5HT2 receptors
KR20230024378A (en) 2020-06-12 2023-02-20 벡클리 싸이테크 리미티드 A composition comprising the benzoate salt of 5-methoxy-N,N-dimethyltryptamine
GB202212116D0 (en) 2022-08-19 2022-10-05 Beckley Psytech Ltd Pharmaceutically acceptable salts and Compositions thereof

Also Published As

Publication number Publication date
NL7216464A (en) 1973-06-13
JPS4864099A (en) 1973-09-05
IE38233L (en) 1973-06-10
HU165738B (en) 1974-10-28
DE2259644A1 (en) 1973-06-14
IL41035A (en) 1975-08-31
AT339509B (en) 1977-10-25
GB1410349A (en) 1975-10-15
FI53819B (en) 1978-05-02
FR2162618A1 (en) 1973-07-20
IE38233B1 (en) 1978-02-01
PL84879B1 (en) 1976-04-30
DD101672A5 (en) 1973-11-12
NO135421C (en) 1977-04-05
IL41035A0 (en) 1973-02-28
BE792515A (en) 1973-06-08
FI53819C (en) 1978-08-10
SE398350B (en) 1977-12-19
NO135421B (en) 1976-12-27
SU461500A3 (en) 1975-02-25
ATA1040772A (en) 1977-02-15
FR2162618B1 (en) 1975-10-17

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