IE37904L - Benzodiazepines. - Google Patents

Benzodiazepines.

Info

Publication number
IE37904L
IE37904L IE731180A IE118073A IE37904L IE 37904 L IE37904 L IE 37904L IE 731180 A IE731180 A IE 731180A IE 118073 A IE118073 A IE 118073A IE 37904 L IE37904 L IE 37904L
Authority
IE
Ireland
Prior art keywords
july
halogen
compound
benzodiazepines
compounds
Prior art date
Application number
IE731180A
Other versions
IE37904B1 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722234150 external-priority patent/DE2234150A1/en
Priority claimed from DE2324962A external-priority patent/DE2324962A1/en
Priority claimed from DE19732326657 external-priority patent/DE2326657A1/en
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IE37904L publication Critical patent/IE37904L/en
Publication of IE37904B1 publication Critical patent/IE37904B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1392143 Benzodiazepines DR KARL THOMAE GmbH 11 July 1973 [12 July 1972 15 May 1973 25 May 1973] 33072/73 Heading C2C Compounds of the general formula (R 1 , 2 = H, C 1-5 alkyl or alkenyl optionally substituted by furyl, dialkylamino, OH, carbalkoxy or carbamido, cycloalkyl, Ph or NR 1 R 2 =pyrrolidino, piperidino, hexamethyleneimino, morpholino, thiamorpholino, thiamorpholine S- oxido, N-alkylpiperazino; R 3 =halogen, CF 3 , NO 2 ;R 4 =H, halogen, CF 3 ;R 5 =H alkyi, cycloalkylmethyl, alkylaminoalkyl, dialkylaminoalkyl, trifluoromethylalkyl) and their acid addition salts are prepared by (a) introducing the 3- substituent, (b) dehydrogenating the corresponding 3-R 1 R 2 NCH 2 - compound or (c) reacting a 3-dialkoxymethyl or hydroxymethylene compound with R 1 R 2 NH, optionally followed by salt formation in each case. The above compounds are sedatives, tranquillizers, muscle relaxants and anticonvulsants, and may be administered in the form of pharmaceutical preparations containing them in association with the carrier. [GB1392143A]
IE1180/73A 1972-07-12 1973-07-12 Benzodiazepines IE37904B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19722234150 DE2234150A1 (en) 1972-07-12 1972-07-12 Benzodiazepin-2-one derivs - tranquillizers, sedatives, muscle relaxants
DE2324962A DE2324962A1 (en) 1973-05-15 1973-05-15 Benzodiazepin-2-one derivs - tranquillizers, sedatives, muscle relaxants
DE19732326657 DE2326657A1 (en) 1973-05-25 1973-05-25 Pharmacologically active 1,4-benzodiazepines - with sedative, tranquillising, muscle-relaxant and anti-convulsive activity

Publications (2)

Publication Number Publication Date
IE37904L true IE37904L (en) 1974-01-12
IE37904B1 IE37904B1 (en) 1977-11-09

Family

ID=27184564

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1180/73A IE37904B1 (en) 1972-07-12 1973-07-12 Benzodiazepines

Country Status (15)

Country Link
JP (1) JPS4985080A (en)
AT (2) AT329572B (en)
AU (1) AU475257B2 (en)
BG (2) BG20374A3 (en)
CA (1) CA1006512A (en)
CH (1) CH590252A5 (en)
CS (1) CS176244B2 (en)
DD (1) DD106172A5 (en)
DK (1) DK138115C (en)
ES (1) ES416780A1 (en)
GB (1) GB1392143A (en)
HU (1) HU167867B (en)
IE (1) IE37904B1 (en)
IL (1) IL42720A (en)
PL (1) PL93110B1 (en)

Also Published As

Publication number Publication date
IL42720A0 (en) 1973-11-28
CA1006512A (en) 1977-03-08
DK138115C (en) 1978-12-18
DK138115B (en) 1978-07-17
AU475257B2 (en) 1976-08-19
ES416780A1 (en) 1976-03-16
BG20374A3 (en) 1975-11-05
AT327922B (en) 1976-02-25
IE37904B1 (en) 1977-11-09
ATA1008574A (en) 1975-08-15
GB1392143A (en) 1975-04-30
CS176244B2 (en) 1977-06-30
BG20802A3 (en) 1975-12-20
AU5799773A (en) 1975-01-16
PL93110B1 (en) 1977-05-30
ATA608873A (en) 1975-05-15
CH590252A5 (en) 1977-07-29
DD106172A5 (en) 1974-06-05
JPS4985080A (en) 1974-08-15
AT329572B (en) 1976-05-25
IL42720A (en) 1976-06-30
HU167867B (en) 1975-12-25

Similar Documents

Publication Publication Date Title
GB1309182A (en) Pyrimidine derivatives
IE34634L (en) Amino-alkoxy styrenes
IE37904L (en) Benzodiazepines.
AU597090B2 (en) 2-acyloxypropylamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
GB1462095A (en) Substituted triazolo-1,5-benzodiazepines
GB1345214A (en) Isoxazoles
GB1431259A (en) 1-substituted-6-phenyl-4h-s-triazolo- 4,3-a- 1,4- benzodiazepines
IE38686B1 (en) 3-hydrazonomethyl rifamycin sv
GB1399590A (en) Imidazoline tranquilizing agents
IE39926B1 (en) Compositions containing indanyloxyalkanoic acid compounds
GB1138315A (en) 2-amino-benzylamines
GB1412891A (en) Sulphamoyl-quinazolinones
GB1472487A (en) Benzodiazepine derivatives
IE34922B1 (en) Pyrimidopyrimidines
GB1389186A (en) Chromone derivatives processes for their manufacture
GB1173701A (en) 5-Substituted-1,4-Benzodiazepines
GB1420780A (en) Medicinal preparation of treatment of malignant neoplasms mostly hemoblastoses and chorionepithelioma
ES378186A1 (en) Azamorphinan compounds
GB1472937A (en) Benzyl alcohol derivatives
GB1281201A (en) 2-iminobenzodiazepine derivatives
GB1313056A (en) Pyrimidopyrimidines
GB1189461A (en) Benzodiazepine Derivatives and their production
GB1440742A (en) 2,3,4,5-tetrahydro-4-phenyl-1h-1,4-benzodiazepine-1-carboximi damide and related compounds
GB1305537A (en)
GB1452506A (en) Pharmaceutical compositions containing anti-allergy drugs