GB1173701A - 5-Substituted-1,4-Benzodiazepines - Google Patents

5-Substituted-1,4-Benzodiazepines

Info

Publication number
GB1173701A
GB1173701A GB1274468A GB1274468A GB1173701A GB 1173701 A GB1173701 A GB 1173701A GB 1274468 A GB1274468 A GB 1274468A GB 1274468 A GB1274468 A GB 1274468A GB 1173701 A GB1173701 A GB 1173701A
Authority
GB
United Kingdom
Prior art keywords
alkyl
alkanoyl
cycloalkyl
march
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1274468A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of GB1173701A publication Critical patent/GB1173701A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,173,701. Benzodiazepine derivatives. SMITH KLINE & FRENCH LABORATORIES. 15 March, 1968 [24 March, 1967], No. 12744/68. Heading C2C. Novel compounds of the general formulµ and (R 1 = Cl or CF 3 , R 2 =H, C 1-4 alkyl, C 2-4 alkanoyl, C 2-5 alkoxycarbonyl, C 3-6 cycloalkyl (C 1-4 alkyl), phenyl or di-(C 1-4 alkyl)-amino (C 1-4 alkyl), R 3 = C 1-4 alkyl or C 3-6 alkenyl, R 4 = H or C 2-4 alkanoyl) and their acid addition salts are prepared by condensing a compound of the formula (X=halogen) with H 2 NCH 2 CH 2 NHR 5 (R 5 =H, C 1-4 alkyl, C 3-6 cycloalkyl (C 1-4 alkyl), phenyl or di-(C 1-4 alkyl) amino (C 1-4 alkyl)) optionally followed by catalytic hydrogenation, acylation and/or salt formation. The compounds of the invention are tranquilizers, and may be administered in the form of pharmaceutical preparations containing them together with a carrier.
GB1274468A 1967-03-24 1968-03-15 5-Substituted-1,4-Benzodiazepines Expired GB1173701A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62563667A 1967-03-24 1967-03-24

Publications (1)

Publication Number Publication Date
GB1173701A true GB1173701A (en) 1969-12-10

Family

ID=24506949

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1274468A Expired GB1173701A (en) 1967-03-24 1968-03-15 5-Substituted-1,4-Benzodiazepines

Country Status (1)

Country Link
GB (1) GB1173701A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369221B1 (en) * 1997-07-28 2002-04-09 Aventis Pharma S.A. Thiazolobenzoheterocycles, preparation and medicines containing same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369221B1 (en) * 1997-07-28 2002-04-09 Aventis Pharma S.A. Thiazolobenzoheterocycles, preparation and medicines containing same

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Legal Events

Date Code Title Description
PS Patent sealed
435 Patent endorsed 'licences of right' on the date specified (sect. 35/1949)
PLNP Patent lapsed through nonpayment of renewal fees