IE36426B1 - Process for preparing injectable compositions - Google Patents
Process for preparing injectable compositionsInfo
- Publication number
- IE36426B1 IE36426B1 IE859/72A IE85972A IE36426B1 IE 36426 B1 IE36426 B1 IE 36426B1 IE 859/72 A IE859/72 A IE 859/72A IE 85972 A IE85972 A IE 85972A IE 36426 B1 IE36426 B1 IE 36426B1
- Authority
- IE
- Ireland
- Prior art keywords
- allergen
- solution
- tyrosine
- particles
- micro
- Prior art date
Links
- 239000007972 injectable composition Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000013566 allergen Substances 0.000 abstract 8
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 4
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 239000011859 microparticle Substances 0.000 abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 241000282326 Felis catus Species 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002009 allergenic effect Effects 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 239000011260 aqueous acid Substances 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 239000000428 dust Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3278071A GB1377074A (en) | 1971-07-13 | 1971-07-13 | Process for preparing injectable compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36426L IE36426L (en) | 1973-01-13 |
| IE36426B1 true IE36426B1 (en) | 1976-10-27 |
Family
ID=10343893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE859/72A IE36426B1 (en) | 1971-07-13 | 1972-06-20 | Process for preparing injectable compositions |
Country Status (14)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1492973A (en) * | 1974-02-16 | 1977-11-23 | Beecham Group Ltd | Process for preparing injectable compositions |
| US4070455A (en) * | 1974-02-16 | 1978-01-24 | Beecham Group Limited | Process for preparing injectable desensitizing compositions and products thereof in microparticle form |
| US4258029A (en) * | 1979-04-23 | 1981-03-24 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
| US4880635B1 (en) * | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
| US5057317A (en) * | 1987-03-24 | 1991-10-15 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
| US4990336A (en) * | 1989-02-08 | 1991-02-05 | Biosearch, Inc. | Sustained release dosage form |
| US5126147A (en) * | 1990-02-08 | 1992-06-30 | Biosearch, Inc. | Sustained release dosage form |
| US5352461A (en) * | 1992-03-11 | 1994-10-04 | Pharmaceutical Discovery Corporation | Self assembling diketopiperazine drug delivery system |
| GB9508785D0 (en) * | 1995-04-29 | 1995-06-21 | Smithkline Beecham Plc | Novel compositions |
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| DK1272211T3 (da) * | 2000-04-07 | 2007-10-01 | Signal Coordinating Therapy In | Fremgangsmåder og sammensætninger til behandling af neoplasmer |
-
1971
- 1971-07-13 GB GB3278071A patent/GB1377074A/en not_active Expired
-
1972
- 1972-06-20 IE IE859/72A patent/IE36426B1/xx unknown
- 1972-07-03 ZA ZA724557A patent/ZA724557B/xx unknown
- 1972-07-06 CA CA146,522A patent/CA973093A/en not_active Expired
- 1972-07-07 BE BE786026D patent/BE786026A/xx not_active IP Right Cessation
- 1972-07-10 US US00270086A patent/US3792159A/en not_active Expired - Lifetime
- 1972-07-10 FR FR7224888A patent/FR2145555B1/fr not_active Expired
- 1972-07-10 NL NLAANVRAGE7209574,A patent/NL176431C/xx not_active IP Right Cessation
- 1972-07-11 ES ES404748A patent/ES404748A1/es not_active Expired
- 1972-07-12 JP JP6986172A patent/JPS5549572B1/ja active Pending
- 1972-07-12 AU AU44505/72A patent/AU462878B2/en not_active Expired
- 1972-07-12 SE SE7209208A patent/SE385770B/xx unknown
- 1972-07-12 DK DK346972AA patent/DK130455B/da not_active IP Right Cessation
- 1972-07-13 DE DE2234474A patent/DE2234474C3/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK130455B (da) | 1975-02-24 |
| US3792159A (en) | 1974-02-12 |
| AU462878B2 (en) | 1975-07-10 |
| FR2145555A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-02-23 |
| IE36426L (en) | 1973-01-13 |
| NL176431C (nl) | 1985-04-16 |
| BE786026A (fr) | 1973-01-08 |
| FR2145555B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-05-14 |
| DE2234474C3 (de) | 1981-06-11 |
| SE385770B (sv) | 1976-07-26 |
| NL7209574A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-01-16 |
| DK130455C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-07-21 |
| GB1377074A (en) | 1974-12-11 |
| CA973093A (en) | 1975-08-19 |
| ES404748A1 (es) | 1975-07-01 |
| DE2234474B2 (de) | 1980-07-24 |
| ZA724557B (en) | 1973-07-25 |
| NL176431B (nl) | 1984-11-16 |
| DE2234474A1 (de) | 1973-01-25 |
| AU4450572A (en) | 1974-01-17 |
| JPS5549572B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1980-12-12 |
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