IE32504B1 - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
IE32504B1
IE32504B1 IE1425/68A IE142568A IE32504B1 IE 32504 B1 IE32504 B1 IE 32504B1 IE 1425/68 A IE1425/68 A IE 1425/68A IE 142568 A IE142568 A IE 142568A IE 32504 B1 IE32504 B1 IE 32504B1
Authority
IE
Ireland
Prior art keywords
alkyl
hal
benzodiazepine derivatives
phch2
subst
Prior art date
Application number
IE1425/68A
Other languages
English (en)
Other versions
IE32504L (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IE32504L publication Critical patent/IE32504L/xx
Publication of IE32504B1 publication Critical patent/IE32504B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE1425/68A 1967-11-24 1968-11-22 Benzodiazepine derivatives IE32504B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (2)

Publication Number Publication Date
IE32504L IE32504L (en) 1969-05-24
IE32504B1 true IE32504B1 (en) 1973-08-22

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1425/68A IE32504B1 (en) 1967-11-24 1968-11-22 Benzodiazepine derivatives

Country Status (13)

Country Link
AT (1) AT280290B (enExample)
BE (1) BE724364A (enExample)
BR (1) BR6804236D0 (enExample)
CH (1) CH523265A (enExample)
DE (1) DE1810423B2 (enExample)
DK (1) DK124950B (enExample)
ES (2) ES360410A1 (enExample)
FR (2) FR1593335A (enExample)
GB (1) GB1173540A (enExample)
IE (1) IE32504B1 (enExample)
IL (1) IL31146A (enExample)
NL (1) NL6815755A (enExample)
SE (1) SE356979B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
US7144880B2 (en) 1999-04-30 2006-12-05 Regents Of The University Of Michigan Compositions relating to novel compounds and targets thereof
IL146222A0 (en) 1999-04-30 2002-07-25 Univ Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
US7638624B2 (en) 2005-01-03 2009-12-29 The Regents Of The University Of Michigan Compositions and methods relating to novel benzodiazepine compounds and derivatives
EP1893218A4 (en) 2005-06-01 2011-01-12 Univ Michigan UNLOCKED BENZODIAZEPINE COMPOSITIONS AND METHOD
CA2628193C (en) 2005-11-01 2012-08-14 The Regents Of The University Of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
EP2037741B1 (en) 2006-06-09 2013-11-27 The Regents Of The University Of Michigan Benzodiazepine derivatives for use in the treatment of immune, inflammatory and proliferative disorders
CN101662940A (zh) 2007-03-09 2010-03-03 密执安州立大学董事会 与新化合物及其靶标有关的组合物和方法
KR20100017766A (ko) 2007-05-10 2010-02-16 에이엠알 테크놀로지, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤조-1,4-디아제핀 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 이의 용도
JP5416122B2 (ja) 2007-09-14 2014-02-12 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Ｆ１Ｆ０−ＡＴＰａｓｅインヒビターおよび関連の方法
RU2010122902A (ru) 2007-11-06 2011-12-20 Дзе Риджентс оф дзе Юниверсити оф Мичиган (US) Бензодиапениноновые соединения, применимые в лечении кожных состояний
JP5567573B2 (ja) 2008-09-11 2014-08-06 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン アリールグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤およびそれと関連する方法
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
US8673897B2 (en) 2009-09-18 2014-03-18 The Regents Of The University Of Michigan Benzodiazepinone compounds and methods of treatment using same
AU2010322287B2 (en) 2009-11-17 2014-04-03 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
CN102753179A (zh) 2009-11-17 2012-10-24 密执安大学评议会 具有治疗性能的1,4-苯并二氮杂*-2,5-二酮和相关化合物
CA2923835C (en) 2013-09-11 2022-11-29 The Administrators Of The Tulane Educational Fund Novel anthranilic amides and the use thereof

Also Published As

Publication number Publication date
DE1810423A1 (de) 1969-10-09
IL31146A (en) 1972-04-27
CH523265A (de) 1972-05-31
GB1173540A (en) 1969-12-10
FR1593335A (enExample) 1970-05-25
AT280290B (de) 1970-04-10
DE1810423B2 (de) 1973-03-22
SE356979B (enExample) 1973-06-12
IL31146A0 (en) 1969-01-29
ES360410A1 (es) 1970-11-01
IE32504L (en) 1969-05-24
NL6815755A (enExample) 1969-05-28
FR8310M (enExample) 1970-11-23
ES378977A1 (es) 1973-01-16
DE1810423C3 (enExample) 1973-10-11
BE724364A (enExample) 1969-05-22
BR6804236D0 (pt) 1973-02-08
DK124950B (da) 1972-12-11

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